Nanobacteria in the pathogenesis of urolithiasis: Myth or reality?

Stone formation in the urinary tract is a common phenomenon with associated morbidity. The exact physicochemical factors responsible for stone formation are not clearly known. Over the past decade considerable interest has been generated in defining the role of nanobacteria in urinary stone formatio...

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Main Authors: Nitin Abrol, Arabind Panda, Nitin S Kekre, Antony Devasia
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Indian Journal of Urology
Subjects:
Online Access:http://www.indianjurol.com/article.asp?issn=0970-1591;year=2015;volume=31;issue=1;spage=3;epage=7;aulast=Abrol
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author Nitin Abrol
Arabind Panda
Nitin S Kekre
Antony Devasia
author_facet Nitin Abrol
Arabind Panda
Nitin S Kekre
Antony Devasia
author_sort Nitin Abrol
collection DOAJ
description Stone formation in the urinary tract is a common phenomenon with associated morbidity. The exact physicochemical factors responsible for stone formation are not clearly known. Over the past decade considerable interest has been generated in defining the role of nanobacteria in urinary stone formation. A review of the available literature has been carried out to give insights into their nature and outline their role in stone formation. The two aspects of nanobacteria that need to be considered include its biological nature and the other merely as mineralo-protein complexes. Though the current literature favors the concept of mineralo-protein particles, further research is needed to clearly define their nature. Whether living or nonliving, these apatite forming nanoparticles appear to play role in kidney stone formation.
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spelling doaj.art-861d081105704434b3fdda1b4cda95fd2022-12-21T19:02:57ZengWolters Kluwer Medknow PublicationsIndian Journal of Urology0970-15911998-38242015-01-013113710.4103/0970-1591.134235Nanobacteria in the pathogenesis of urolithiasis: Myth or reality?Nitin AbrolArabind PandaNitin S KekreAntony DevasiaStone formation in the urinary tract is a common phenomenon with associated morbidity. The exact physicochemical factors responsible for stone formation are not clearly known. Over the past decade considerable interest has been generated in defining the role of nanobacteria in urinary stone formation. A review of the available literature has been carried out to give insights into their nature and outline their role in stone formation. The two aspects of nanobacteria that need to be considered include its biological nature and the other merely as mineralo-protein complexes. Though the current literature favors the concept of mineralo-protein particles, further research is needed to clearly define their nature. Whether living or nonliving, these apatite forming nanoparticles appear to play role in kidney stone formation.http://www.indianjurol.com/article.asp?issn=0970-1591;year=2015;volume=31;issue=1;spage=3;epage=7;aulast=AbrolCalcifying nanoparticlesfetuinkidney stonesmineralo-protein complexesnanobacteria
spellingShingle Nitin Abrol
Arabind Panda
Nitin S Kekre
Antony Devasia
Nanobacteria in the pathogenesis of urolithiasis: Myth or reality?
Indian Journal of Urology
Calcifying nanoparticles
fetuin
kidney stones
mineralo-protein complexes
nanobacteria
title Nanobacteria in the pathogenesis of urolithiasis: Myth or reality?
title_full Nanobacteria in the pathogenesis of urolithiasis: Myth or reality?
title_fullStr Nanobacteria in the pathogenesis of urolithiasis: Myth or reality?
title_full_unstemmed Nanobacteria in the pathogenesis of urolithiasis: Myth or reality?
title_short Nanobacteria in the pathogenesis of urolithiasis: Myth or reality?
title_sort nanobacteria in the pathogenesis of urolithiasis myth or reality
topic Calcifying nanoparticles
fetuin
kidney stones
mineralo-protein complexes
nanobacteria
url http://www.indianjurol.com/article.asp?issn=0970-1591;year=2015;volume=31;issue=1;spage=3;epage=7;aulast=Abrol
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AT arabindpanda nanobacteriainthepathogenesisofurolithiasismythorreality
AT nitinskekre nanobacteriainthepathogenesisofurolithiasismythorreality
AT antonydevasia nanobacteriainthepathogenesisofurolithiasismythorreality