Adult mesenchymal stem cells and their possibilities for Dentistry: what to expect?

ABSTRACT Introduction: Stem cells obtained from the pulp of human deciduous teeth are highly proliferative and plastic multipotent cells, which makes them a relevant model of stem cells, applied in several biomedical areas, with different purposes. Objective: Based on a brief review of the literat...

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Main Authors: José Ricardo Muniz Ferreira, Anna Paula Greck
Format: Article
Language:English
Published: Dental Press Editora 2020-08-01
Series:Dental Press Journal of Orthodontics
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512020000300085&tlng=en
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author José Ricardo Muniz Ferreira
Anna Paula Greck
author_facet José Ricardo Muniz Ferreira
Anna Paula Greck
author_sort José Ricardo Muniz Ferreira
collection DOAJ
description ABSTRACT Introduction: Stem cells obtained from the pulp of human deciduous teeth are highly proliferative and plastic multipotent cells, which makes them a relevant model of stem cells, applied in several biomedical areas, with different purposes. Objective: Based on a brief review of the literature, the present work intends to present from conceptual aspects about stem cells, classifications, potential (in vitro and in vivo) applications in dental practice, cell culture, cryopreservation and its importance, ethical and regulatory aspects, as well as the role of the dental surgeon as the endorser responsible for the entire clinical stage that involves the process of collecting stem cells obtained from dental pulps for cryopreservation, with a view to using them under appropriate conditions, in accordance with scientifically proven and justified good laboratory and clinical practices.
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spelling doaj.art-861df8069ee94d8bb56955a44ceadf1d2022-12-21T21:03:19ZengDental Press EditoraDental Press Journal of Orthodontics2177-67092020-08-01253859210.1590/2177-6709.25.3.085-092.sarAdult mesenchymal stem cells and their possibilities for Dentistry: what to expect?José Ricardo Muniz Ferreirahttps://orcid.org/0000-0002-5192-5623Anna Paula Greckhttps://orcid.org/0000-0003-0772-0572ABSTRACT Introduction: Stem cells obtained from the pulp of human deciduous teeth are highly proliferative and plastic multipotent cells, which makes them a relevant model of stem cells, applied in several biomedical areas, with different purposes. Objective: Based on a brief review of the literature, the present work intends to present from conceptual aspects about stem cells, classifications, potential (in vitro and in vivo) applications in dental practice, cell culture, cryopreservation and its importance, ethical and regulatory aspects, as well as the role of the dental surgeon as the endorser responsible for the entire clinical stage that involves the process of collecting stem cells obtained from dental pulps for cryopreservation, with a view to using them under appropriate conditions, in accordance with scientifically proven and justified good laboratory and clinical practices.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512020000300085&tlng=enMesenchymal stem cellsRegenerative dentistryCell therapyTissue bioengineeringCryopreservation
spellingShingle José Ricardo Muniz Ferreira
Anna Paula Greck
Adult mesenchymal stem cells and their possibilities for Dentistry: what to expect?
Dental Press Journal of Orthodontics
Mesenchymal stem cells
Regenerative dentistry
Cell therapy
Tissue bioengineering
Cryopreservation
title Adult mesenchymal stem cells and their possibilities for Dentistry: what to expect?
title_full Adult mesenchymal stem cells and their possibilities for Dentistry: what to expect?
title_fullStr Adult mesenchymal stem cells and their possibilities for Dentistry: what to expect?
title_full_unstemmed Adult mesenchymal stem cells and their possibilities for Dentistry: what to expect?
title_short Adult mesenchymal stem cells and their possibilities for Dentistry: what to expect?
title_sort adult mesenchymal stem cells and their possibilities for dentistry what to expect
topic Mesenchymal stem cells
Regenerative dentistry
Cell therapy
Tissue bioengineering
Cryopreservation
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512020000300085&tlng=en
work_keys_str_mv AT josericardomunizferreira adultmesenchymalstemcellsandtheirpossibilitiesfordentistrywhattoexpect
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