Features of calcium signaling in ischemic injury nervous tissue – of neurons in the hippocampus
This review describes the features of the systems to ensure the restoration of calcium homeostasis of hippocampal neurons during ischemic injury. High levels of intracellular Ca 2+ , glutamate excitotoxicity activity and the formation of free radicals during ischemia are a major damaging factors, le...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Taras Shevchenko National University of Kyiv
2016-07-01
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| Series: | Vìsnik: Kiïvsʹkij Nacìonalʹnij Unìversitet Imenì Tarasa Ševčenka. Bìologìâ |
| Subjects: | |
| Online Access: | http://biovestnik.com/index.php/biology/article/view/60 |
| _version_ | 1797715855800270848 |
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| author | A. Maistrenko N. Voitenko |
| author_facet | A. Maistrenko N. Voitenko |
| author_sort | A. Maistrenko |
| collection | DOAJ |
| description | This review describes the features of the systems to ensure the restoration of calcium homeostasis of hippocampal neurons during ischemic injury. High levels of intracellular Ca 2+ , glutamate excitotoxicity activity and the formation of free radicals during ischemia are a major damaging factors, leading to further damage to hippocampal neurons. Understanding the mechanisms able to prevent the development of damage today is key for the development of post- and preconditioning neuroprotective strategies. |
| first_indexed | 2024-03-12T08:12:59Z |
| format | Article |
| id | doaj.art-86241fed53e64f34a471fe7516cc1ca1 |
| institution | Directory Open Access Journal |
| issn | 1728-2748 2308-8036 |
| language | English |
| last_indexed | 2024-03-12T08:12:59Z |
| publishDate | 2016-07-01 |
| publisher | Taras Shevchenko National University of Kyiv |
| record_format | Article |
| series | Vìsnik: Kiïvsʹkij Nacìonalʹnij Unìversitet Imenì Tarasa Ševčenka. Bìologìâ |
| spelling | doaj.art-86241fed53e64f34a471fe7516cc1ca12023-09-02T19:06:26ZengTaras Shevchenko National University of KyivVìsnik: Kiïvsʹkij Nacìonalʹnij Unìversitet Imenì Tarasa Ševčenka. Bìologìâ1728-27482308-80362016-07-01702707310.17721/1728_2748.2015.70.70-7360Features of calcium signaling in ischemic injury nervous tissue – of neurons in the hippocampusA. Maistrenko0N. Voitenko1Bogomoletz Institute of Physiology NASU, KyivBogomoletz Institute of Physiology NASU, KyivThis review describes the features of the systems to ensure the restoration of calcium homeostasis of hippocampal neurons during ischemic injury. High levels of intracellular Ca 2+ , glutamate excitotoxicity activity and the formation of free radicals during ischemia are a major damaging factors, leading to further damage to hippocampal neurons. Understanding the mechanisms able to prevent the development of damage today is key for the development of post- and preconditioning neuroprotective strategies.http://biovestnik.com/index.php/biology/article/view/60SERCA – Ca2+-ATPase of endoplasmic reticulum, PMCA – Ca2+ATP-ASE of plasmatic membrane, ischemic injury, the hippocampus |
| spellingShingle | A. Maistrenko N. Voitenko Features of calcium signaling in ischemic injury nervous tissue – of neurons in the hippocampus Vìsnik: Kiïvsʹkij Nacìonalʹnij Unìversitet Imenì Tarasa Ševčenka. Bìologìâ SERCA – Ca2+-ATPase of endoplasmic reticulum, PMCA – Ca2+ATP-ASE of plasmatic membrane, ischemic injury, the hippocampus |
| title | Features of calcium signaling in ischemic injury nervous tissue – of neurons in the hippocampus |
| title_full | Features of calcium signaling in ischemic injury nervous tissue – of neurons in the hippocampus |
| title_fullStr | Features of calcium signaling in ischemic injury nervous tissue – of neurons in the hippocampus |
| title_full_unstemmed | Features of calcium signaling in ischemic injury nervous tissue – of neurons in the hippocampus |
| title_short | Features of calcium signaling in ischemic injury nervous tissue – of neurons in the hippocampus |
| title_sort | features of calcium signaling in ischemic injury nervous tissue of neurons in the hippocampus |
| topic | SERCA – Ca2+-ATPase of endoplasmic reticulum, PMCA – Ca2+ATP-ASE of plasmatic membrane, ischemic injury, the hippocampus |
| url | http://biovestnik.com/index.php/biology/article/view/60 |
| work_keys_str_mv | AT amaistrenko featuresofcalciumsignalinginischemicinjurynervoustissueofneuronsinthehippocampus AT nvoitenko featuresofcalciumsignalinginischemicinjurynervoustissueofneuronsinthehippocampus |