Solid Papillary Carcinoma with Invasion in the Male Breast: A Case Report and Literature Review

Introduction: Solid papillary carcinoma (SPC) accounts for approximately 1% of all breast cancer cases and occurs primarily in postmenopausal women. We report a rare SPC with invasion in the male breast. Case Presentation: A 73-year-old Japanese man presented with bloody nipple discharge and a palpa...

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Main Authors: Hideko Hoshina, Kouichi Kubouchi, Hiroyuki Takei
Format: Article
Language:English
Published: Karger Publishers 2024-01-01
Series:Case Reports in Oncology
Subjects:
Online Access:https://beta.karger.com/Article/FullText/536034
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author Hideko Hoshina
Kouichi Kubouchi
Hiroyuki Takei
author_facet Hideko Hoshina
Kouichi Kubouchi
Hiroyuki Takei
author_sort Hideko Hoshina
collection DOAJ
description Introduction: Solid papillary carcinoma (SPC) accounts for approximately 1% of all breast cancer cases and occurs primarily in postmenopausal women. We report a rare SPC with invasion in the male breast. Case Presentation: A 73-year-old Japanese man presented with bloody nipple discharge and a palpable left breast mass. Mammography revealed a well-defined high-concentration mass. Ultrasonography scans demonstrated an intracystic 10 mm mass under the left nipple without enlarged axillary lymph nodes. A core needle biopsy revealed a ductal carcinoma with nuclear grade 1, which excluded an invasive carcinoma. Magnetic resonance imaging exhibited a 7 mm intense early enhancement in the left breast. A left mastectomy and sentinel lymph node biopsy were performed. The patient was diagnosed with pathological stage IA (T1b N0 M0) breast carcinoma, an invasive pure SPC type without neuroendocrine markers. The patient was treated with oral tamoxifen and survived without any recurrence for 12 months. Conclusion: Invasive SPC of the male breast may occur as a palpable mass or nipple discharge in older men and has a good prognosis.
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spelling doaj.art-8624582394e341549dc3108f7e8935ad2024-02-22T13:43:57ZengKarger PublishersCase Reports in Oncology1662-65752024-01-0117113514110.1159/000536034536034Solid Papillary Carcinoma with Invasion in the Male Breast: A Case Report and Literature ReviewHideko Hoshina0Kouichi Kubouchi1Hiroyuki Takei2Yokohama Breast Clinic, Kanagawa, JapanYokohama Breast Clinic, Kanagawa, JapanDepartment of Breast Surgery and Oncology, Nippon Medical School, Tokyo, JapanIntroduction: Solid papillary carcinoma (SPC) accounts for approximately 1% of all breast cancer cases and occurs primarily in postmenopausal women. We report a rare SPC with invasion in the male breast. Case Presentation: A 73-year-old Japanese man presented with bloody nipple discharge and a palpable left breast mass. Mammography revealed a well-defined high-concentration mass. Ultrasonography scans demonstrated an intracystic 10 mm mass under the left nipple without enlarged axillary lymph nodes. A core needle biopsy revealed a ductal carcinoma with nuclear grade 1, which excluded an invasive carcinoma. Magnetic resonance imaging exhibited a 7 mm intense early enhancement in the left breast. A left mastectomy and sentinel lymph node biopsy were performed. The patient was diagnosed with pathological stage IA (T1b N0 M0) breast carcinoma, an invasive pure SPC type without neuroendocrine markers. The patient was treated with oral tamoxifen and survived without any recurrence for 12 months. Conclusion: Invasive SPC of the male breast may occur as a palpable mass or nipple discharge in older men and has a good prognosis.https://beta.karger.com/Article/FullText/536034invasive solid papillary carcinomasolid papillary carcinoma with invasionmale breast cancerneuroendocrine differentiation
spellingShingle Hideko Hoshina
Kouichi Kubouchi
Hiroyuki Takei
Solid Papillary Carcinoma with Invasion in the Male Breast: A Case Report and Literature Review
Case Reports in Oncology
invasive solid papillary carcinoma
solid papillary carcinoma with invasion
male breast cancer
neuroendocrine differentiation
title Solid Papillary Carcinoma with Invasion in the Male Breast: A Case Report and Literature Review
title_full Solid Papillary Carcinoma with Invasion in the Male Breast: A Case Report and Literature Review
title_fullStr Solid Papillary Carcinoma with Invasion in the Male Breast: A Case Report and Literature Review
title_full_unstemmed Solid Papillary Carcinoma with Invasion in the Male Breast: A Case Report and Literature Review
title_short Solid Papillary Carcinoma with Invasion in the Male Breast: A Case Report and Literature Review
title_sort solid papillary carcinoma with invasion in the male breast a case report and literature review
topic invasive solid papillary carcinoma
solid papillary carcinoma with invasion
male breast cancer
neuroendocrine differentiation
url https://beta.karger.com/Article/FullText/536034
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AT hiroyukitakei solidpapillarycarcinomawithinvasioninthemalebreastacasereportandliteraturereview