A data-independent acquisition-based global phosphoproteomics system enables deep profiling
Phosphoproteomics can provide systematic insights into disease-associated cell signaling changes. Here, the authors present a sensitive workflow integrating library-based and direct data-independent acquisition approaches, and a hybrid spectral library resource for in-depth phosphoproteomic profilin...
Main Authors: | Reta Birhanu Kitata, Wai-Kok Choong, Chia-Feng Tsai, Pei-Yi Lin, Bo-Shiun Chen, Yun-Chien Chang, Alexey I. Nesvizhskii, Ting-Yi Sung, Yu-Ju Chen |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-05-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-22759-z |
Similar Items
-
Streamlined single-cell proteomics by an integrated microfluidic chip and data-independent acquisition mass spectrometry
by: Sofani Tafesse Gebreyesus, et al.
Published: (2022-01-01) -
A streamlined tandem tip-based workflow for sensitive nanoscale phosphoproteomics
by: Chia-Feng Tsai, et al.
Published: (2023-01-01) -
Concentration levels of major and trace metals in onion (<i>Allium cepa</i> L.) and irrigation water around Meki Town and Lake Ziway, Ethiopia
by: Reta Birhanu Kitata, et al.
Published: (2012-12-01) -
Rapid and site-specific deep phosphoproteome profiling by data-independent acquisition without the need for spectral libraries
by: Dorte B. Bekker-Jensen, et al.
Published: (2020-02-01) -
Phosphoproteomics identifies oncogenic Ras signaling targets and their involvement in lung adenocarcinomas.
by: Putty-Reddy Sudhir, et al.
Published: (2011-01-01)