Comparative Analysis of Corneal Higher-Order Aberrations after Laser-Assisted In Situ Keratomileusis, Photorefractive Keratectomy, and Small Incision Lenticule Extraction with Correlations to Change in Myopic Q-Value and Spherical Equivalent with and without Astigmatism

<b>Background</b>: This retrospective chart review compared the higher-order aberrations (HOAs) among photorefractive keratectomy (PRK), laser-assisted in situ keratomileusis (LASIK), and small incision lenticule extraction (SMILE) alongside changes in spherical equivalent (SEQ) and corn...

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Main Authors: Majid Moshirfar, Soroush Omidvarnia, Michael T. Christensen, Kaiden B. Porter, Josh S. Theis, Nathan M. Olson, Isabella M. Stoakes, Carter J. Payne, Phillip C. Hoopes
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/13/7/1906
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author Majid Moshirfar
Soroush Omidvarnia
Michael T. Christensen
Kaiden B. Porter
Josh S. Theis
Nathan M. Olson
Isabella M. Stoakes
Carter J. Payne
Phillip C. Hoopes
author_facet Majid Moshirfar
Soroush Omidvarnia
Michael T. Christensen
Kaiden B. Porter
Josh S. Theis
Nathan M. Olson
Isabella M. Stoakes
Carter J. Payne
Phillip C. Hoopes
author_sort Majid Moshirfar
collection DOAJ
description <b>Background</b>: This retrospective chart review compared the higher-order aberrations (HOAs) among photorefractive keratectomy (PRK), laser-assisted in situ keratomileusis (LASIK), and small incision lenticule extraction (SMILE) alongside changes in spherical equivalent (SEQ) and corneal shape (Q-value). <b>Methods</b>: Analyzing 371 myopic eyes, including 154 LASIK, 173 PRK, and 44 SMILE cases, Pentacam imaging was utilized pre-operatively and at one-year post-operative visits. <b>Results</b>: All procedures resulted in 100% of patients achieving an uncorrected distance visual acuity (UDVA) of 20/40 or better, with 87% of LASIK and PRK, and 91% of SMILE patients having 20/20 or better. Significant increases in HOAs were observed across all procedures (<i>p</i> < 0.05), correlating positively with SEQ and Q-value changes (LASIK (0.686, <i>p</i> < 0.05), followed by PRK (0.4503, <i>p</i> < 0.05), and SMILE (0.386, <i>p</i> < 0.05)). Vertical coma and spherical aberration (SA) were the primary factors for heightened aberration magnitude among the procedures (<i>p</i> < 0.05), with the largest contribution in SMILE, which is likely attributed to the centration at the corneal apex. Notably, PRK showed insignificant changes in vertical coma (−0.197 µm ± 0.0168 to −0.192 µm ± 0.0198, <i>p</i> = 0.78), with an increase in oblique trefoil (<i>p</i> < 0.05). <b>Conclusions</b>: These findings underscore differences in HOAs among PRK, LASIK, and SMILE, helping to guide clinicians.
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spelling doaj.art-8627c1314ebf43a9934021e126cea0fd2024-04-12T13:20:59ZengMDPI AGJournal of Clinical Medicine2077-03832024-03-01137190610.3390/jcm13071906Comparative Analysis of Corneal Higher-Order Aberrations after Laser-Assisted In Situ Keratomileusis, Photorefractive Keratectomy, and Small Incision Lenticule Extraction with Correlations to Change in Myopic Q-Value and Spherical Equivalent with and without AstigmatismMajid Moshirfar0Soroush Omidvarnia1Michael T. Christensen2Kaiden B. Porter3Josh S. Theis4Nathan M. Olson5Isabella M. Stoakes6Carter J. Payne7Phillip C. Hoopes8Hoopes Vision Research Center, Hoopes Vision, 11820 S. State St., Ste. 200, Draper, UT 84020, USASchool of Medicine, Texas Tech University, Lubbock, TX 79409, USASchool of Medicine, Wake Forest University, Winston Salem, NC 27103, USASchool of Medicine, University of Arizona, Phoenix, AZ 85004, USASchool of Medicine, University of Arizona, Phoenix, AZ 85004, USACollege of Osteopathic Medicine, Rocky Vista University, Ivins, UT 84738, USAHoopes Vision Research Center, Hoopes Vision, 11820 S. State St., Ste. 200, Draper, UT 84020, USAHoopes Vision Research Center, Hoopes Vision, 11820 S. State St., Ste. 200, Draper, UT 84020, USAHoopes Vision Research Center, Hoopes Vision, 11820 S. State St., Ste. 200, Draper, UT 84020, USA<b>Background</b>: This retrospective chart review compared the higher-order aberrations (HOAs) among photorefractive keratectomy (PRK), laser-assisted in situ keratomileusis (LASIK), and small incision lenticule extraction (SMILE) alongside changes in spherical equivalent (SEQ) and corneal shape (Q-value). <b>Methods</b>: Analyzing 371 myopic eyes, including 154 LASIK, 173 PRK, and 44 SMILE cases, Pentacam imaging was utilized pre-operatively and at one-year post-operative visits. <b>Results</b>: All procedures resulted in 100% of patients achieving an uncorrected distance visual acuity (UDVA) of 20/40 or better, with 87% of LASIK and PRK, and 91% of SMILE patients having 20/20 or better. Significant increases in HOAs were observed across all procedures (<i>p</i> < 0.05), correlating positively with SEQ and Q-value changes (LASIK (0.686, <i>p</i> < 0.05), followed by PRK (0.4503, <i>p</i> < 0.05), and SMILE (0.386, <i>p</i> < 0.05)). Vertical coma and spherical aberration (SA) were the primary factors for heightened aberration magnitude among the procedures (<i>p</i> < 0.05), with the largest contribution in SMILE, which is likely attributed to the centration at the corneal apex. Notably, PRK showed insignificant changes in vertical coma (−0.197 µm ± 0.0168 to −0.192 µm ± 0.0198, <i>p</i> = 0.78), with an increase in oblique trefoil (<i>p</i> < 0.05). <b>Conclusions</b>: These findings underscore differences in HOAs among PRK, LASIK, and SMILE, helping to guide clinicians.https://www.mdpi.com/2077-0383/13/7/1906higher-order aberrationsvertical comahorizontal comatrefoilspherical aberrationsLASIK
spellingShingle Majid Moshirfar
Soroush Omidvarnia
Michael T. Christensen
Kaiden B. Porter
Josh S. Theis
Nathan M. Olson
Isabella M. Stoakes
Carter J. Payne
Phillip C. Hoopes
Comparative Analysis of Corneal Higher-Order Aberrations after Laser-Assisted In Situ Keratomileusis, Photorefractive Keratectomy, and Small Incision Lenticule Extraction with Correlations to Change in Myopic Q-Value and Spherical Equivalent with and without Astigmatism
Journal of Clinical Medicine
higher-order aberrations
vertical coma
horizontal coma
trefoil
spherical aberrations
LASIK
title Comparative Analysis of Corneal Higher-Order Aberrations after Laser-Assisted In Situ Keratomileusis, Photorefractive Keratectomy, and Small Incision Lenticule Extraction with Correlations to Change in Myopic Q-Value and Spherical Equivalent with and without Astigmatism
title_full Comparative Analysis of Corneal Higher-Order Aberrations after Laser-Assisted In Situ Keratomileusis, Photorefractive Keratectomy, and Small Incision Lenticule Extraction with Correlations to Change in Myopic Q-Value and Spherical Equivalent with and without Astigmatism
title_fullStr Comparative Analysis of Corneal Higher-Order Aberrations after Laser-Assisted In Situ Keratomileusis, Photorefractive Keratectomy, and Small Incision Lenticule Extraction with Correlations to Change in Myopic Q-Value and Spherical Equivalent with and without Astigmatism
title_full_unstemmed Comparative Analysis of Corneal Higher-Order Aberrations after Laser-Assisted In Situ Keratomileusis, Photorefractive Keratectomy, and Small Incision Lenticule Extraction with Correlations to Change in Myopic Q-Value and Spherical Equivalent with and without Astigmatism
title_short Comparative Analysis of Corneal Higher-Order Aberrations after Laser-Assisted In Situ Keratomileusis, Photorefractive Keratectomy, and Small Incision Lenticule Extraction with Correlations to Change in Myopic Q-Value and Spherical Equivalent with and without Astigmatism
title_sort comparative analysis of corneal higher order aberrations after laser assisted in situ keratomileusis photorefractive keratectomy and small incision lenticule extraction with correlations to change in myopic q value and spherical equivalent with and without astigmatism
topic higher-order aberrations
vertical coma
horizontal coma
trefoil
spherical aberrations
LASIK
url https://www.mdpi.com/2077-0383/13/7/1906
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