Evaluating Mobius3D Dose Calculation Accuracy for Small-Field Flattening- Filter-Free Photon Beams
Purpose: We aimed to investigate the dose calculation accuracy of Mobius3D for small-field flattening-filter-free x-rays, mainly utilized for stereotactic body radiation therapy (SBRT). The accuracy of beam modeling and multileaf collimator (MLC) modeling in Mobius3D, significantly affecting the dos...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2022-12-01
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| Series: | Technology in Cancer Research & Treatment |
| Online Access: | https://doi.org/10.1177/15330338221141542 |
| _version_ | 1828074859725324288 |
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| author | Changhwan Kim PhD Jihun Kim PhD Young Kyu Lee PhD Han-Back Shin PhD Min Cheol Han PhD Hojin Kim PhD Jin Sung Kim PhD |
| author_facet | Changhwan Kim PhD Jihun Kim PhD Young Kyu Lee PhD Han-Back Shin PhD Min Cheol Han PhD Hojin Kim PhD Jin Sung Kim PhD |
| author_sort | Changhwan Kim PhD |
| collection | DOAJ |
| description | Purpose: We aimed to investigate the dose calculation accuracy of Mobius3D for small-field flattening-filter-free x-rays, mainly utilized for stereotactic body radiation therapy (SBRT). The accuracy of beam modeling and multileaf collimator (MLC) modeling in Mobius3D, significantly affecting the dose calculation is investigated. Methods: The commissioning procedures of Mobius3D were performed for unflattened 6 MV and 10 MV x-ray beams of the linear accelerator, including beam model adjustment and dosimetric leaf gap (DLG) optimization. An experimental study with artificial plans was conducted to evaluate the accuracy of small-field modeling. The dose calculation accuracy of Mobius3D was also evaluated for retrospective SBRT plans with multiple targets. Results: Both studies evaluated the dose calculation accuracy through comparisons with the measured data. Relatively large differences were observed for off-axis distances over 5 cm and for small fields less than 1 cm field size. For the study with artificial plans, the maximum absolute error of 9.96% for unflattened 6 MV and 9.07% for unflattened 10 MV was observed when the field size was 1 cm. For the study with patient plans, the mean gamma passing rate with 3%/3 mm gamma criterion was 63.6% for unflattened 6 MV and 82.6% for unflattened 10 MV. The maximum of the average dose difference was −19.9% for unflattened 6MV and −10.1% for unflattened 10MV. Conclusions: The dose calculation accuracy uncertainties of Mobius3D for small-field flattening-filter-free photon beams were observed. The study results indicated that the beam and MLC modeling of Mobius3D must be improved for use in SBRT pretreatment QA in clinical practice. |
| first_indexed | 2024-04-11T01:50:01Z |
| format | Article |
| id | doaj.art-86293e893a794ee99e68dff2ab8dbc33 |
| institution | Directory Open Access Journal |
| issn | 1533-0338 |
| language | English |
| last_indexed | 2024-04-11T01:50:01Z |
| publishDate | 2022-12-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Technology in Cancer Research & Treatment |
| spelling | doaj.art-86293e893a794ee99e68dff2ab8dbc332023-01-03T06:33:22ZengSAGE PublishingTechnology in Cancer Research & Treatment1533-03382022-12-012110.1177/15330338221141542Evaluating Mobius3D Dose Calculation Accuracy for Small-Field Flattening- Filter-Free Photon BeamsChanghwan Kim PhD0Jihun Kim PhD1Young Kyu Lee PhD2Han-Back Shin PhD3Min Cheol Han PhD4Hojin Kim PhD5Jin Sung Kim PhD6 Department of Radiation Oncology, Yonsei Cancer Center, , Seoul, South Korea Department of Radiation Oncology, Gangnam Severance Hospital, , Seoul, South Korea Department of Radiation Oncology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea Department of Radiation Oncology, Yonsei Cancer Center, , Seoul, South Korea Department of Radiation Oncology, Yonsei Cancer Center, , Seoul, South Korea Department of Radiation Oncology, Yonsei Cancer Center, , Seoul, South Korea Department of Radiation Oncology, Yonsei Cancer Center, , Seoul, South KoreaPurpose: We aimed to investigate the dose calculation accuracy of Mobius3D for small-field flattening-filter-free x-rays, mainly utilized for stereotactic body radiation therapy (SBRT). The accuracy of beam modeling and multileaf collimator (MLC) modeling in Mobius3D, significantly affecting the dose calculation is investigated. Methods: The commissioning procedures of Mobius3D were performed for unflattened 6 MV and 10 MV x-ray beams of the linear accelerator, including beam model adjustment and dosimetric leaf gap (DLG) optimization. An experimental study with artificial plans was conducted to evaluate the accuracy of small-field modeling. The dose calculation accuracy of Mobius3D was also evaluated for retrospective SBRT plans with multiple targets. Results: Both studies evaluated the dose calculation accuracy through comparisons with the measured data. Relatively large differences were observed for off-axis distances over 5 cm and for small fields less than 1 cm field size. For the study with artificial plans, the maximum absolute error of 9.96% for unflattened 6 MV and 9.07% for unflattened 10 MV was observed when the field size was 1 cm. For the study with patient plans, the mean gamma passing rate with 3%/3 mm gamma criterion was 63.6% for unflattened 6 MV and 82.6% for unflattened 10 MV. The maximum of the average dose difference was −19.9% for unflattened 6MV and −10.1% for unflattened 10MV. Conclusions: The dose calculation accuracy uncertainties of Mobius3D for small-field flattening-filter-free photon beams were observed. The study results indicated that the beam and MLC modeling of Mobius3D must be improved for use in SBRT pretreatment QA in clinical practice.https://doi.org/10.1177/15330338221141542 |
| spellingShingle | Changhwan Kim PhD Jihun Kim PhD Young Kyu Lee PhD Han-Back Shin PhD Min Cheol Han PhD Hojin Kim PhD Jin Sung Kim PhD Evaluating Mobius3D Dose Calculation Accuracy for Small-Field Flattening- Filter-Free Photon Beams Technology in Cancer Research & Treatment |
| title | Evaluating Mobius3D Dose Calculation Accuracy for Small-Field Flattening-
Filter-Free Photon Beams |
| title_full | Evaluating Mobius3D Dose Calculation Accuracy for Small-Field Flattening-
Filter-Free Photon Beams |
| title_fullStr | Evaluating Mobius3D Dose Calculation Accuracy for Small-Field Flattening-
Filter-Free Photon Beams |
| title_full_unstemmed | Evaluating Mobius3D Dose Calculation Accuracy for Small-Field Flattening-
Filter-Free Photon Beams |
| title_short | Evaluating Mobius3D Dose Calculation Accuracy for Small-Field Flattening-
Filter-Free Photon Beams |
| title_sort | evaluating mobius3d dose calculation accuracy for small field flattening filter free photon beams |
| url | https://doi.org/10.1177/15330338221141542 |
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