Does Waldenstrom’s macroglobulinemia also cause bone destruction? A rare case report
Waldenstrom’s macroglobulinemia (WM) is a rare type of malignant B-cell lymphoma. The main feature of WM is elevated serum monoclonal immunoglobulin M, similar to multiple myeloma (MM). Unlike in MM, the rarity of destructive bone lesions in WM has been repeatedly emphasized. We report a unique case...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2022-04-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/03000605221096161 |
| _version_ | 1811307124326662144 |
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| author | Jun-Ming Lin Xiao-Jun Yuan Lu Zhang Guang Li Xin-rong Gan Wen-Hua Xu |
| author_facet | Jun-Ming Lin Xiao-Jun Yuan Lu Zhang Guang Li Xin-rong Gan Wen-Hua Xu |
| author_sort | Jun-Ming Lin |
| collection | DOAJ |
| description | Waldenstrom’s macroglobulinemia (WM) is a rare type of malignant B-cell lymphoma. The main feature of WM is elevated serum monoclonal immunoglobulin M, similar to multiple myeloma (MM). Unlike in MM, the rarity of destructive bone lesions in WM has been repeatedly emphasized. We report a unique case of WM with a vertebral compression fracture as the first symptom. This case highlights that the presence or absence of bone destruction may not clearly distinguish between WM and MM. The possibility of WM should be considered in patients with vertebral fracture and destruction as the first presentation. Performing vertebral bone marrow aspiration biopsy during percutaneous vertebroplasty is a convenient and effective method to assist in the diagnosis of WM. |
| first_indexed | 2024-04-13T08:59:01Z |
| format | Article |
| id | doaj.art-86297b8996f14920ab2da95d0aa177da |
| institution | Directory Open Access Journal |
| issn | 1473-2300 |
| language | English |
| last_indexed | 2024-04-13T08:59:01Z |
| publishDate | 2022-04-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj.art-86297b8996f14920ab2da95d0aa177da2022-12-22T02:53:12ZengSAGE PublishingJournal of International Medical Research1473-23002022-04-015010.1177/03000605221096161Does Waldenstrom’s macroglobulinemia also cause bone destruction? A rare case reportJun-Ming LinXiao-Jun YuanLu ZhangGuang LiXin-rong GanWen-Hua XuWaldenstrom’s macroglobulinemia (WM) is a rare type of malignant B-cell lymphoma. The main feature of WM is elevated serum monoclonal immunoglobulin M, similar to multiple myeloma (MM). Unlike in MM, the rarity of destructive bone lesions in WM has been repeatedly emphasized. We report a unique case of WM with a vertebral compression fracture as the first symptom. This case highlights that the presence or absence of bone destruction may not clearly distinguish between WM and MM. The possibility of WM should be considered in patients with vertebral fracture and destruction as the first presentation. Performing vertebral bone marrow aspiration biopsy during percutaneous vertebroplasty is a convenient and effective method to assist in the diagnosis of WM.https://doi.org/10.1177/03000605221096161 |
| spellingShingle | Jun-Ming Lin Xiao-Jun Yuan Lu Zhang Guang Li Xin-rong Gan Wen-Hua Xu Does Waldenstrom’s macroglobulinemia also cause bone destruction? A rare case report Journal of International Medical Research |
| title | Does Waldenstrom’s macroglobulinemia also cause bone destruction? A rare case report |
| title_full | Does Waldenstrom’s macroglobulinemia also cause bone destruction? A rare case report |
| title_fullStr | Does Waldenstrom’s macroglobulinemia also cause bone destruction? A rare case report |
| title_full_unstemmed | Does Waldenstrom’s macroglobulinemia also cause bone destruction? A rare case report |
| title_short | Does Waldenstrom’s macroglobulinemia also cause bone destruction? A rare case report |
| title_sort | does waldenstrom s macroglobulinemia also cause bone destruction a rare case report |
| url | https://doi.org/10.1177/03000605221096161 |
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