Ileum and colon perforation following peritoneal dialysis-related peritonitis and high-dose calcium polystyrene sulfonate
A rare but severe complication, intestinal necrosis, has been reported after sodium polystyrene sulfonate (SPS; Kayexalate) and sorbitol intake. Some case reports described bowel perforation following calcium polystyrene sulfonate (CPS; Kalimate) administration. We report a case of ileum and colon p...
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| Format: | Article |
| Language: | English |
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Elsevier
2015-10-01
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| Series: | Journal of the Formosan Medical Association |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0929664613000910 |
| _version_ | 1828834807721754624 |
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| author | Chih-Chin Kao Yi-Chiun Tsai Wen-Chih Chiang Tsui-Lien Mao Tze-Wah Kao |
| author_facet | Chih-Chin Kao Yi-Chiun Tsai Wen-Chih Chiang Tsui-Lien Mao Tze-Wah Kao |
| author_sort | Chih-Chin Kao |
| collection | DOAJ |
| description | A rare but severe complication, intestinal necrosis, has been reported after sodium polystyrene sulfonate (SPS; Kayexalate) and sorbitol intake. Some case reports described bowel perforation following calcium polystyrene sulfonate (CPS; Kalimate) administration. We report a case of ileum and colon perforation following peritoneal dialysis-related peritonitis and high-dose Kalimate in a 59-year-old female patient. The patient had a history of hypertension, diabetes mellitus, and end-stage renal disease (ESRD). During hospitalization for peritoneal dialysis-related peritonitis, she developed hyperkalemia, and Kalimate was administered orally. However, severe abdominal distension and pain occurred just one day after Kalimate intake. An urgent surgery disclosed several perforations in the ileum and sigmoid colon. Pathology of the resected gut showed transmural necrosis and perforation with basophilic angulated crystals. The patient finally expired during hospitalization due to refractory septic shock. |
| first_indexed | 2024-12-12T17:46:54Z |
| format | Article |
| id | doaj.art-8629831f77a94284ac27eea8804694a7 |
| institution | Directory Open Access Journal |
| issn | 0929-6646 |
| language | English |
| last_indexed | 2024-12-12T17:46:54Z |
| publishDate | 2015-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of the Formosan Medical Association |
| spelling | doaj.art-8629831f77a94284ac27eea8804694a72022-12-22T00:16:54ZengElsevierJournal of the Formosan Medical Association0929-66462015-10-01114101008101010.1016/j.jfma.2013.02.006Ileum and colon perforation following peritoneal dialysis-related peritonitis and high-dose calcium polystyrene sulfonateChih-Chin Kao0Yi-Chiun Tsai1Wen-Chih Chiang2Tsui-Lien Mao3Tze-Wah Kao4Division of Nephrology, Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University, College of Medicine, Taipei, TaiwanDivision of Nephrology, Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University, College of Medicine, Taipei, TaiwanDivision of Nephrology, Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University, College of Medicine, Taipei, TaiwanDepartment of Pathology, National Taiwan University Hospital, National Taiwan University, College of Medicine, Taipei, TaiwanDivision of Nephrology, Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University, College of Medicine, Taipei, TaiwanA rare but severe complication, intestinal necrosis, has been reported after sodium polystyrene sulfonate (SPS; Kayexalate) and sorbitol intake. Some case reports described bowel perforation following calcium polystyrene sulfonate (CPS; Kalimate) administration. We report a case of ileum and colon perforation following peritoneal dialysis-related peritonitis and high-dose Kalimate in a 59-year-old female patient. The patient had a history of hypertension, diabetes mellitus, and end-stage renal disease (ESRD). During hospitalization for peritoneal dialysis-related peritonitis, she developed hyperkalemia, and Kalimate was administered orally. However, severe abdominal distension and pain occurred just one day after Kalimate intake. An urgent surgery disclosed several perforations in the ileum and sigmoid colon. Pathology of the resected gut showed transmural necrosis and perforation with basophilic angulated crystals. The patient finally expired during hospitalization due to refractory septic shock.http://www.sciencedirect.com/science/article/pii/S0929664613000910bowel/intestinal perforationend-stage renal diseaseKalimate |
| spellingShingle | Chih-Chin Kao Yi-Chiun Tsai Wen-Chih Chiang Tsui-Lien Mao Tze-Wah Kao Ileum and colon perforation following peritoneal dialysis-related peritonitis and high-dose calcium polystyrene sulfonate Journal of the Formosan Medical Association bowel/intestinal perforation end-stage renal disease Kalimate |
| title | Ileum and colon perforation following peritoneal dialysis-related peritonitis and high-dose calcium polystyrene sulfonate |
| title_full | Ileum and colon perforation following peritoneal dialysis-related peritonitis and high-dose calcium polystyrene sulfonate |
| title_fullStr | Ileum and colon perforation following peritoneal dialysis-related peritonitis and high-dose calcium polystyrene sulfonate |
| title_full_unstemmed | Ileum and colon perforation following peritoneal dialysis-related peritonitis and high-dose calcium polystyrene sulfonate |
| title_short | Ileum and colon perforation following peritoneal dialysis-related peritonitis and high-dose calcium polystyrene sulfonate |
| title_sort | ileum and colon perforation following peritoneal dialysis related peritonitis and high dose calcium polystyrene sulfonate |
| topic | bowel/intestinal perforation end-stage renal disease Kalimate |
| url | http://www.sciencedirect.com/science/article/pii/S0929664613000910 |
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