Thyroid Carcinoma: A Review for 25 Years of Environmental Risk Factors Studies
Environmental factors are established contributors to thyroid carcinomas. Due to their known ability to cause cancer, exposure to several organic and inorganic chemical toxicants and radiation from nuclear weapons, fallout, or medical radiation poses a threat to global public health. Halogenated sub...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/14/24/6172 |
| _version_ | 1797461090023505920 |
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| author | Eva Kruger Eman A. Toraih Mohammad H. Hussein Shaimaa A. Shehata Amani Waheed Manal S. Fawzy Emad Kandil |
| author_facet | Eva Kruger Eman A. Toraih Mohammad H. Hussein Shaimaa A. Shehata Amani Waheed Manal S. Fawzy Emad Kandil |
| author_sort | Eva Kruger |
| collection | DOAJ |
| description | Environmental factors are established contributors to thyroid carcinomas. Due to their known ability to cause cancer, exposure to several organic and inorganic chemical toxicants and radiation from nuclear weapons, fallout, or medical radiation poses a threat to global public health. Halogenated substances like organochlorines and pesticides can interfere with thyroid function. Like phthalates and bisphenolates, polychlorinated biphenyls and their metabolites, along with polybrominated diethyl ethers, impact thyroid hormones biosynthesis, transport, binding to target organs, and impair thyroid function. A deeper understanding of environmental exposure is crucial for managing and preventing thyroid cancer. This review aims to investigate the relationship between environmental factors and the development of thyroid cancer. |
| first_indexed | 2024-03-09T17:14:27Z |
| format | Article |
| id | doaj.art-862a2c0455814d3da7bf1786bd321b53 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-09T17:14:27Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-862a2c0455814d3da7bf1786bd321b532023-11-24T13:47:33ZengMDPI AGCancers2072-66942022-12-011424617210.3390/cancers14246172Thyroid Carcinoma: A Review for 25 Years of Environmental Risk Factors StudiesEva Kruger0Eman A. Toraih1Mohammad H. Hussein2Shaimaa A. Shehata3Amani Waheed4Manal S. Fawzy5Emad Kandil6School of Medicine, Tulane University, New Orleans, LA 70112, USADivision of Endocrine and Oncologic Surgery, Department of Surgery, School of Medicine, Tulane University, New Orleans, LA 70112, USADivision of Endocrine and Oncologic Surgery, Department of Surgery, School of Medicine, Tulane University, New Orleans, LA 70112, USADepartment of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Suez Canal University, Ismailia 41522, EgyptDepartment of Community Medicine, Faculty of Medicine, Suez Canal University, Ismailia 41522, EgyptDepartment of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Suez Canal University, Ismailia 41522, EgyptDivision of Endocrine and Oncologic Surgery, Department of Surgery, School of Medicine, Tulane University, New Orleans, LA 70112, USAEnvironmental factors are established contributors to thyroid carcinomas. Due to their known ability to cause cancer, exposure to several organic and inorganic chemical toxicants and radiation from nuclear weapons, fallout, or medical radiation poses a threat to global public health. Halogenated substances like organochlorines and pesticides can interfere with thyroid function. Like phthalates and bisphenolates, polychlorinated biphenyls and their metabolites, along with polybrominated diethyl ethers, impact thyroid hormones biosynthesis, transport, binding to target organs, and impair thyroid function. A deeper understanding of environmental exposure is crucial for managing and preventing thyroid cancer. This review aims to investigate the relationship between environmental factors and the development of thyroid cancer.https://www.mdpi.com/2072-6694/14/24/6172thyroidcancerriskenvironmentradiationendocrine disrupting chemicals |
| spellingShingle | Eva Kruger Eman A. Toraih Mohammad H. Hussein Shaimaa A. Shehata Amani Waheed Manal S. Fawzy Emad Kandil Thyroid Carcinoma: A Review for 25 Years of Environmental Risk Factors Studies Cancers thyroid cancer risk environment radiation endocrine disrupting chemicals |
| title | Thyroid Carcinoma: A Review for 25 Years of Environmental Risk Factors Studies |
| title_full | Thyroid Carcinoma: A Review for 25 Years of Environmental Risk Factors Studies |
| title_fullStr | Thyroid Carcinoma: A Review for 25 Years of Environmental Risk Factors Studies |
| title_full_unstemmed | Thyroid Carcinoma: A Review for 25 Years of Environmental Risk Factors Studies |
| title_short | Thyroid Carcinoma: A Review for 25 Years of Environmental Risk Factors Studies |
| title_sort | thyroid carcinoma a review for 25 years of environmental risk factors studies |
| topic | thyroid cancer risk environment radiation endocrine disrupting chemicals |
| url | https://www.mdpi.com/2072-6694/14/24/6172 |
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