Experimentally testing the role of blood vessels in the full scattering profile: solid phantom measurements
Optical methods for biomedical purposes mostly use reflected light, while few of them use the transmitted light. The blood vessels pose a challenge to these methods due to their high absorption and scattering coefficients as well as their change in size during respiration, and they are also naturall...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Samara National Research University
2016-12-01
|
| Series: | Journal of Biomedical Photonics & Engineering |
| Subjects: | |
| Online Access: | http://jbpe.ssau.ru/index.php/JBPE/article/view/3096 |
| _version_ | 1818544551795621888 |
|---|---|
| author | Idit Feder Hamootal Duadi Moti Fridman Tamar Dreifuss Dror Fixler |
| author_facet | Idit Feder Hamootal Duadi Moti Fridman Tamar Dreifuss Dror Fixler |
| author_sort | Idit Feder |
| collection | DOAJ |
| description | Optical methods for biomedical purposes mostly use reflected light, while few of them use the transmitted light. The blood vessels pose a challenge to these methods due to their high absorption and scattering coefficients as well as their change in size during respiration, and they are also naturally distributed in size within the body and between individuals. We suggest the full scattering profile (FSP) method in order to investigate the light at every possible exit angle. Our model of FSP successfully describes the role of the blood vessel diameter in light-tissue interaction. By means of the new point of view of FSP, we found the isobaric point, which is non-dependent on the optical properties. The uniqueness of the isobaric point is that it overcomes the shielding effect, which has known influence on the reflected light, for various vascular diameters of the same volume. We present these findings experimentally by measuring cylindrical phantoms with blood vessels in different diameters, and compare the results to our simulation results. The importance of the immunity to the shielding effect is that it allows self-calibration in clinical measurements and decreases the calibration error. In addition, by using the isobaric point we can cope with changes in blood vessel diameters and not assume microcirculation only. |
| first_indexed | 2024-12-11T22:49:59Z |
| format | Article |
| id | doaj.art-862a55b309de4de3836bb8a8530f0181 |
| institution | Directory Open Access Journal |
| issn | 2411-2844 |
| language | English |
| last_indexed | 2024-12-11T22:49:59Z |
| publishDate | 2016-12-01 |
| publisher | Samara National Research University |
| record_format | Article |
| series | Journal of Biomedical Photonics & Engineering |
| spelling | doaj.art-862a55b309de4de3836bb8a8530f01812022-12-22T00:47:28ZengSamara National Research UniversityJournal of Biomedical Photonics & Engineering2411-28442016-12-012410.18287/JBPE16.02.0403012902Experimentally testing the role of blood vessels in the full scattering profile: solid phantom measurementsIdit Feder0Hamootal Duadi1Moti Fridman2Tamar Dreifuss3Dror Fixler4Faculty of Engineering and the Institute of Nanotechnology and Advanced Materials, Bar Ilan University, IsraelFaculty of Engineering and the Institute of Nanotechnology and Advanced Materials, Bar Ilan University, IsraelFaculty of Engineering and the Institute of Nanotechnology and Advanced Materials, Bar Ilan University, IsraelFaculty of Engineering and the Institute of Nanotechnology and Advanced Materials, Bar Ilan University, IsraelFaculty of Engineering and the Institute of Nanotechnology and Advanced Materials, Bar Ilan University, IsraelOptical methods for biomedical purposes mostly use reflected light, while few of them use the transmitted light. The blood vessels pose a challenge to these methods due to their high absorption and scattering coefficients as well as their change in size during respiration, and they are also naturally distributed in size within the body and between individuals. We suggest the full scattering profile (FSP) method in order to investigate the light at every possible exit angle. Our model of FSP successfully describes the role of the blood vessel diameter in light-tissue interaction. By means of the new point of view of FSP, we found the isobaric point, which is non-dependent on the optical properties. The uniqueness of the isobaric point is that it overcomes the shielding effect, which has known influence on the reflected light, for various vascular diameters of the same volume. We present these findings experimentally by measuring cylindrical phantoms with blood vessels in different diameters, and compare the results to our simulation results. The importance of the immunity to the shielding effect is that it allows self-calibration in clinical measurements and decreases the calibration error. In addition, by using the isobaric point we can cope with changes in blood vessel diameters and not assume microcirculation only.http://jbpe.ssau.ru/index.php/JBPE/article/view/3096absorptionlight impulsebiophotonicsmedical physics |
| spellingShingle | Idit Feder Hamootal Duadi Moti Fridman Tamar Dreifuss Dror Fixler Experimentally testing the role of blood vessels in the full scattering profile: solid phantom measurements Journal of Biomedical Photonics & Engineering absorption light impulse biophotonics medical physics |
| title | Experimentally testing the role of blood vessels in the full scattering profile: solid phantom measurements |
| title_full | Experimentally testing the role of blood vessels in the full scattering profile: solid phantom measurements |
| title_fullStr | Experimentally testing the role of blood vessels in the full scattering profile: solid phantom measurements |
| title_full_unstemmed | Experimentally testing the role of blood vessels in the full scattering profile: solid phantom measurements |
| title_short | Experimentally testing the role of blood vessels in the full scattering profile: solid phantom measurements |
| title_sort | experimentally testing the role of blood vessels in the full scattering profile solid phantom measurements |
| topic | absorption light impulse biophotonics medical physics |
| url | http://jbpe.ssau.ru/index.php/JBPE/article/view/3096 |
| work_keys_str_mv | AT iditfeder experimentallytestingtheroleofbloodvesselsinthefullscatteringprofilesolidphantommeasurements AT hamootalduadi experimentallytestingtheroleofbloodvesselsinthefullscatteringprofilesolidphantommeasurements AT motifridman experimentallytestingtheroleofbloodvesselsinthefullscatteringprofilesolidphantommeasurements AT tamardreifuss experimentallytestingtheroleofbloodvesselsinthefullscatteringprofilesolidphantommeasurements AT drorfixler experimentallytestingtheroleofbloodvesselsinthefullscatteringprofilesolidphantommeasurements |