Fulvic Acid Attenuates Atopic Dermatitis by Downregulating CCL17/22

Fulvic Acid Attenuates Atopic Dermatitis by Downregulating CCL17/22

The main pathogenic factor in atopic dermatitis (AD) is Th2 inflammation, and levels of serum CCL17 and CCL22 are related to severity in AD patients. Fulvic acid (FA) is a kind of natural humic acid with anti-inflammatory, antibacterial, and immunomodulatory effects. Our experiments demonstrated the...

Full description

Bibliographic Details
Main Authors:	Chenxi Wu, Anqi Lyu, Shijun Shan
Format:	Article
Language:	English
Published:	MDPI AG 2023-04-01
Series:	Molecules
Subjects:	atopic dermatitis (AD) fulvic acid (FA) CCL17 CCL22
Online Access:	https://www.mdpi.com/1420-3049/28/8/3507

Similar Items

CHEMOKINES CCL17 AND CCL22 IN SARCOIDOSIS
by: N. M. Lazareva, et al.
Published: (2021-10-01)

Personalized multi-marker panel in the risk assessment of atopic dermatitis phenotypes in children
by: Volodymyr Dytiatkovskyi, et al.
Published: (2023-06-01)

CCL17, CCL22 and their receptor CCR4 in hematologic malignancies
by: Shasha Zou, et al.
Published: (2024-09-01)

High loading-dose of dupilumab resulted in rapid disease control in pediatric patients with atopic dermatitis
by: Ao Wang, et al.
Published: (2023-04-01)

Positive association between pruritus and high expression of CCL17, CCL22 and substance P in bullous pemphigoid lesions
by: Manman ZHANG, et al.
Published: (2022-12-01)

Clinical and Immunological Effects of a Forest Trip in Children with Asthma and Atopic Dermatitis
by: Sung Chul Seo, et al.
Published: (2015-02-01)

Assessment of Role s100A7 and Eotaxin (CCL24) in Patients with Atopic Dermatitis in Babylon City
by: Mahmoud Mohsen Muhammad, et al.
Published: (2023-09-01)

Spatial Transcriptomics Analysis Reveals that CCL17 and CCL22 are Robust Indicators of a Suppressive Immune Environment in Angioimmunoblastic T Cell Lymphoma (AITL)
by: Jun Du, et al.
Published: (2022-09-01)

IL-22 in Atopic Dermatitis
by: Julia Laska, et al.
Published: (2024-08-01)

Analytical Performance of a Novel Latex Turbidimetric Immunoassay, “Nanopia TARC”, for TARC/CCL17 Measurement: A Retrospective Observational Study
by: Keita Yamashita, et al.
Published: (2023-09-01)

<i>Polyopes affinis</i> Suppressed IFN-γ- and TNF-α-Induced Inflammation in Human Keratinocytes via Down-Regulation of the NF-κB and STAT1 Pathways
by: Yuna Ha, et al.
Published: (2022-03-01)

Clinical Significance of Combined Detection of CCL22 and IL‐1 as Potential New Bronchial Inflammatory Mediators in Children's Asthma
by: Lei Cui, et al.
Published: (2024-11-01)

Serum CCL22 Increased in Advanced Melanoma Patients with Liver Metastases: Report of 5 Cases
by: Kentaro Ohuchi, et al.
Published: (2022-12-01)

CCL17 and CCL22 chemokines are upregulated in human obesity and play a role in vascular dysfunction
by: Luisa Hueso, et al.
Published: (2023-04-01)

Expression of Helper and Regulatory T Cells in Atopic Dermatitis: A Meta-Analysis
by: Dao-jun Zhang, et al.
Published: (2022-04-01)

Bexarotene Reduces Production of CCL22 From Tumor-Associated Macrophages in Cutaneous T-Cell Lymphoma
by: Kayo Tanita, et al.
Published: (2019-09-01)

Genetic Polymorphisms of CCL22 and CCR4 in Patients with Lung Cancer
by: Nasrollah Erfani, et al.
Published: (2015-07-01)

Allergen sensitization stratifies IL-31 production by memory T cells in atopic dermatitis patients
by: Lídia Sans-de San Nicolàs, et al.
Published: (2023-03-01)

CCR4 Blockade Diminishes Intratumoral Macrophage Recruitment and Augments Survival of Syngeneic Pancreatic Cancer-Bearing Mice
by: Aydar Khabipov, et al.
Published: (2023-05-01)

CCL22 as an independent prognostic factor in endometrial cancer patients
by: Mareike Mannewitz, et al.
Published: (2024-12-01)

CCL22-Polarized TAMs to M2a Macrophages in Cervical Cancer In Vitro Model
by: Qun Wang, et al.
Published: (2022-06-01)

CCL22-based peptide vaccines induce anti-cancer immunity by modulating tumor microenvironment
by: Inés Lecoq, et al.
Published: (2022-12-01)

CCR4 C1014T and CCL22 C16A Genetic Variations in the Iranian Patients with Colorectal Adenocarcinoma
by: Nasrollah Erfani, et al.
Published: (2014-12-01)

THE CHEMOKINE CCL17/TARC AS A BIOMARKER IN HODGKIN LYMPHOMA
by: Maike Sauer, et al.
Published: (2013-08-01)

Comparative Study of the Effect of 5,6-Dihydroergosterol and 3-<i>epi</i>-5,6-dihydroergosterol on Chemokine Expression in Human Keratinocytes
by: Ye Seul Park, et al.
Published: (2020-01-01)

Systemic treatments in atopic dermatitis in children
by: Deniz İlgün Gürel, et al.
Published: (2023-12-01)

HUCMSC‐derived Exosomes Suppress the Titanium Particles‐induced Osteolysis in Mice through Inhibiting CCL2 and CCL3
by: Shixun Li, et al.
Published: (2023-03-01)

CCR7‐CCL19/CCL21 Axis is Essential for Effective Arteriogenesis in a Murine Model of Hindlimb Ischemia
by: A. Yaël Nossent, et al.
Published: (2017-03-01)

Correlation of Early and Late Ejection Fractions with CCL5 and CCL18 Levels in Acute Anterior Myocardial Infarction
by: Mahdi Sajedi Khania, et al.
Published: (2016-06-01)

Autoimmunity (or Not) in Atopic Dermatitis
by: Lennart M. Roesner, et al.
Published: (2019-09-01)

CCL22 and Leptin associated with steroid resistance in childhood idiopathic nephrotic syndrome
by: Peng Zhaoyang, et al.
Published: (2023-09-01)

Linking Dentistry and Chronic Inflammatory Autoimmune Diseases – Can Oral and Jawbone Stressors Affect Systemic Symptoms of Atopic Dermatitis? A Case Report
by: Schick F, et al.
Published: (2022-06-01)

Adsorption of fulvic acid on clay subfractions isolated from mineral horizons of peat-podzol-gley soil
by: K. A. Kolchanova, et al.
Published: (2024-11-01)

Keratin 17 Promotes T Cell Response in Allergic Contact Dermatitis by Upregulating C–C Motif Chemokine Ligand 20
by: Yixin Luo, et al.
Published: (2022-02-01)

Pexidartinib synergize PD-1 antibody through inhibiting treg infiltration by reducing TAM-derived CCL22 in lung adenocarcinoma
by: Wei Zhang, et al.
Published: (2023-03-01)

The expression of CCL17 and potential prognostic value on tumor immunity in thyroid carcinoma based on bioinformatics analysis
by: Xue Gu, et al.
Published: (2024-12-01)

A Study of IFN-α-Induced Chemokines CCL2, CXCL10 and CCL19 in Patients with Systemic Lupus Erythematosu
by: Mariela Gencheva Geneva-Popova, et al.
Published: (2022-02-01)

Accuracy of CCL20 expression level as a liquid biopsy-based diagnostic biomarker for ovarian carcinoma
by: Watchara Sakares, et al.
Published: (2022-10-01)

Gene expression pattern of CCL2, CCL3, and CXCL8 in patients with bipolar disorder
by: Mohsen Ghoryani, et al.
Published: (2019-01-01)

IL-4 Modulates CCL11 and CCL20 Productions from IL-1β-Stimulated Human Periodontal Ligament Cells
by: Yoshitaka Hosokawa, et al.
Published: (2016-01-01)