Factors associated with extubation time in coronary artery bypass grafting patients

Background and Objectives. Cardiovascular diseases are the leading cause of death worldwide, with coronary artery disease being the most common. With increasing numbers of patients, Coronary Artery Bypass Grafting (CABG) has become the most common operation in the world. Respiratory disorder is one...

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Main Authors: Abbas Rezaianzadeh, Behzad Maghsoudi, Hamidreza Tabatabaee, Sareh Keshavarzi, Zahra Bagheri, Javad Sajedianfard, Hamid Gerami, Javad Rasouli
Format: Article
Language:English
Published: PeerJ Inc. 2015-12-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/1414.pdf
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author Abbas Rezaianzadeh
Behzad Maghsoudi
Hamidreza Tabatabaee
Sareh Keshavarzi
Zahra Bagheri
Javad Sajedianfard
Hamid Gerami
Javad Rasouli
author_facet Abbas Rezaianzadeh
Behzad Maghsoudi
Hamidreza Tabatabaee
Sareh Keshavarzi
Zahra Bagheri
Javad Sajedianfard
Hamid Gerami
Javad Rasouli
author_sort Abbas Rezaianzadeh
collection DOAJ
description Background and Objectives. Cardiovascular diseases are the leading cause of death worldwide, with coronary artery disease being the most common. With increasing numbers of patients, Coronary Artery Bypass Grafting (CABG) has become the most common operation in the world. Respiratory disorder is one of the most prevalent complications of CABG. Thus, weaning off the mechanical ventilation and extubation are of great clinical importance for these patients. Some post-operative problems also relate to the tracheal tube and mechanical ventilation. Therefore, an increase in this leads to an increase in the number of complications, length of hospital stay, and treatment costs. Since a large number of factors affect the post-operative period, the present study aims to identify the predictors of extubation time in CABG patients using casualty network analysis.Method. This longitudinal study was conducted on 800 over 18 year old patients who had undergone CABG surgery in three treatment centers affiliated to Shiraz University of Medical Sciences. The patients’ information, including pre-operative, peri-operative, and post-operative variables, was retrospectively extracted from their medical records. Then, the data was comprehensively analyzed through path analysis using MPLUS-7.1 software.Results. The mean of extubation time was 10.27 + 4.39 h. Moreover, extubation time was significantly affected by packed cells during the Cardiopulmonary Bypass (CPB), packed cells after CPB, inotrope use on arrival at ICU, mean arterial pressure 1st ICU, packed cells 1st ICU, platelets 1st ICU, Blood Urea Nitrogen 1st ICU, and hematocrit 1st ICU.Conclusion. Considering all of the factors under investigation, some peri-operative and post-operative factors had significant effects. Therefore, considering the post-operative factors is important for designing a treatment plan and evaluating patients’ prognosis.
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spelling doaj.art-863b629140c5417c9785a40051074dd02023-12-03T11:21:00ZengPeerJ Inc.PeerJ2167-83592015-12-013e141410.7717/peerj.1414Factors associated with extubation time in coronary artery bypass grafting patientsAbbas Rezaianzadeh0Behzad Maghsoudi1Hamidreza Tabatabaee2Sareh Keshavarzi3Zahra Bagheri4Javad Sajedianfard5Hamid Gerami6Javad Rasouli7Colorectal Research Center, Department of epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Anesthesia, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz Fars, IranDepartment of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz Fars, IranDepartment of Biostatistic, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Physiology, School of Veterinary Medicine, Shiraz University, Shiraz, IranDepartment of Anesthesia, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz Fars, IranBackground and Objectives. Cardiovascular diseases are the leading cause of death worldwide, with coronary artery disease being the most common. With increasing numbers of patients, Coronary Artery Bypass Grafting (CABG) has become the most common operation in the world. Respiratory disorder is one of the most prevalent complications of CABG. Thus, weaning off the mechanical ventilation and extubation are of great clinical importance for these patients. Some post-operative problems also relate to the tracheal tube and mechanical ventilation. Therefore, an increase in this leads to an increase in the number of complications, length of hospital stay, and treatment costs. Since a large number of factors affect the post-operative period, the present study aims to identify the predictors of extubation time in CABG patients using casualty network analysis.Method. This longitudinal study was conducted on 800 over 18 year old patients who had undergone CABG surgery in three treatment centers affiliated to Shiraz University of Medical Sciences. The patients’ information, including pre-operative, peri-operative, and post-operative variables, was retrospectively extracted from their medical records. Then, the data was comprehensively analyzed through path analysis using MPLUS-7.1 software.Results. The mean of extubation time was 10.27 + 4.39 h. Moreover, extubation time was significantly affected by packed cells during the Cardiopulmonary Bypass (CPB), packed cells after CPB, inotrope use on arrival at ICU, mean arterial pressure 1st ICU, packed cells 1st ICU, platelets 1st ICU, Blood Urea Nitrogen 1st ICU, and hematocrit 1st ICU.Conclusion. Considering all of the factors under investigation, some peri-operative and post-operative factors had significant effects. Therefore, considering the post-operative factors is important for designing a treatment plan and evaluating patients’ prognosis.https://peerj.com/articles/1414.pdfCoronary Artery BypassRisk factorsExtubation
spellingShingle Abbas Rezaianzadeh
Behzad Maghsoudi
Hamidreza Tabatabaee
Sareh Keshavarzi
Zahra Bagheri
Javad Sajedianfard
Hamid Gerami
Javad Rasouli
Factors associated with extubation time in coronary artery bypass grafting patients
PeerJ
Coronary Artery Bypass
Risk factors
Extubation
title Factors associated with extubation time in coronary artery bypass grafting patients
title_full Factors associated with extubation time in coronary artery bypass grafting patients
title_fullStr Factors associated with extubation time in coronary artery bypass grafting patients
title_full_unstemmed Factors associated with extubation time in coronary artery bypass grafting patients
title_short Factors associated with extubation time in coronary artery bypass grafting patients
title_sort factors associated with extubation time in coronary artery bypass grafting patients
topic Coronary Artery Bypass
Risk factors
Extubation
url https://peerj.com/articles/1414.pdf
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