Contrast-enhanced Ultrasound for Evaluation of Active Needle Tract Bleeding during Thermal Ablation of Liver Cancer
ObjectiveTo investigate the accuracy of contrast-enhanced ultrasound (CEUS) in the diagnosis and localization of active needle-tract bleeding (ANTB) during thermal ablation for liver cancer. MethodsBetween June 2013 and December 2018, liver cancer patients with poor coagulation function or suspected...
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| Format: | Article |
| Language: | English |
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Editorial Office of Advanced Ultrasound in Diagnosis and Therapy
2022-09-01
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| Series: | Advanced Ultrasound in Diagnosis and Therapy |
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| Online Access: | http://www.journaladvancedultrasound.com:81/fileup/2576-2516/PDF/1659941738529-763204809.pdf |
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| author | Huolin Ye, MD, Qiannan Huang, MD, Qingjing Zeng, MD, Xuqi He, MD, Erjiao Xu, MD, Yinglin Long, MD, Kai Li, MD, Rongqin Zheng, MD |
| author_facet | Huolin Ye, MD, Qiannan Huang, MD, Qingjing Zeng, MD, Xuqi He, MD, Erjiao Xu, MD, Yinglin Long, MD, Kai Li, MD, Rongqin Zheng, MD |
| author_sort | Huolin Ye, MD, Qiannan Huang, MD, Qingjing Zeng, MD, Xuqi He, MD, Erjiao Xu, MD, Yinglin Long, MD, Kai Li, MD, Rongqin Zheng, MD |
| collection | DOAJ |
| description | ObjectiveTo investigate the accuracy of contrast-enhanced ultrasound (CEUS) in the diagnosis and localization of active needle-tract bleeding (ANTB) during thermal ablation for liver cancer. MethodsBetween June 2013 and December 2018, liver cancer patients with poor coagulation function or suspected needle-tract bleeding during ablation were enrolled in the study. Conventional US and CEUS were applied to detect ANTB and the bleeding sites, and sequentially abdominal paracentesis drainage (APD) was used as the gold standard for the diagnosis of ANTB. Thermal ablation guided by conventional US or CEUS was used to stop the bleeding. Results Among the 77 enrolled patients, 21 patients (27.3%, 21/77) had ANTB. In total, four (19.0%) and 21 (100%) cases of ANTB were diagnosed by colour Doppler US and CEUS, respectively. The sensitivity, specificity and accuracy of colour Doppler US for diagnosing ANTB were 19.0%, 100% and 77.6%, respectively. The sensitivity, specificity, and accuracy of CEUS for diagnosing ANTB were 100%, 100% and 100%, respectively. The sensitivity of CEUS to diagnose ANTB was significantly higher than that of colour Doppler US (P < 0.001). All cases of ANTB were arterial bleeding and were stopped by thermal ablation under the guidance of colour Doppler US or CEUS. ConclusionCompared to colour Doppler US, CEUS could detect ANTB with significantly higher sensitivity and accurately guide needle-tract ablation during thermal ablation of liver cancer. |
| first_indexed | 2024-04-13T19:57:28Z |
| format | Article |
| id | doaj.art-864473cf6aa94b6e9428511f1e3c898f |
| institution | Directory Open Access Journal |
| issn | 2576-2516 |
| language | English |
| last_indexed | 2024-04-13T19:57:28Z |
| publishDate | 2022-09-01 |
| publisher | Editorial Office of Advanced Ultrasound in Diagnosis and Therapy |
| record_format | Article |
| series | Advanced Ultrasound in Diagnosis and Therapy |
| spelling | doaj.art-864473cf6aa94b6e9428511f1e3c898f2022-12-22T02:32:17ZengEditorial Office of Advanced Ultrasound in Diagnosis and TherapyAdvanced Ultrasound in Diagnosis and Therapy2576-25162022-09-016310411110.37015/AUDT.2021.210019Contrast-enhanced Ultrasound for Evaluation of Active Needle Tract Bleeding during Thermal Ablation of Liver CancerHuolin Ye, MD, Qiannan Huang, MD, Qingjing Zeng, MD, Xuqi He, MD, Erjiao Xu, MD, Yinglin Long, MD, Kai Li, MD, Rongqin Zheng, MD0a Department of Ultrasound, Guangdong Key Laboratory of Liver Disease Research, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China;b Department of Ultrasound, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, ChinaObjectiveTo investigate the accuracy of contrast-enhanced ultrasound (CEUS) in the diagnosis and localization of active needle-tract bleeding (ANTB) during thermal ablation for liver cancer. MethodsBetween June 2013 and December 2018, liver cancer patients with poor coagulation function or suspected needle-tract bleeding during ablation were enrolled in the study. Conventional US and CEUS were applied to detect ANTB and the bleeding sites, and sequentially abdominal paracentesis drainage (APD) was used as the gold standard for the diagnosis of ANTB. Thermal ablation guided by conventional US or CEUS was used to stop the bleeding. Results Among the 77 enrolled patients, 21 patients (27.3%, 21/77) had ANTB. In total, four (19.0%) and 21 (100%) cases of ANTB were diagnosed by colour Doppler US and CEUS, respectively. The sensitivity, specificity and accuracy of colour Doppler US for diagnosing ANTB were 19.0%, 100% and 77.6%, respectively. The sensitivity, specificity, and accuracy of CEUS for diagnosing ANTB were 100%, 100% and 100%, respectively. The sensitivity of CEUS to diagnose ANTB was significantly higher than that of colour Doppler US (P < 0.001). All cases of ANTB were arterial bleeding and were stopped by thermal ablation under the guidance of colour Doppler US or CEUS. ConclusionCompared to colour Doppler US, CEUS could detect ANTB with significantly higher sensitivity and accurately guide needle-tract ablation during thermal ablation of liver cancer.http://www.journaladvancedultrasound.com:81/fileup/2576-2516/PDF/1659941738529-763204809.pdf|contrast-enhanced ultrasound|ablation techniques|liver cancer|haemorrhage |
| spellingShingle | Huolin Ye, MD, Qiannan Huang, MD, Qingjing Zeng, MD, Xuqi He, MD, Erjiao Xu, MD, Yinglin Long, MD, Kai Li, MD, Rongqin Zheng, MD Contrast-enhanced Ultrasound for Evaluation of Active Needle Tract Bleeding during Thermal Ablation of Liver Cancer Advanced Ultrasound in Diagnosis and Therapy |contrast-enhanced ultrasound|ablation techniques|liver cancer|haemorrhage |
| title | Contrast-enhanced Ultrasound for Evaluation of Active Needle Tract Bleeding during Thermal Ablation of Liver Cancer |
| title_full | Contrast-enhanced Ultrasound for Evaluation of Active Needle Tract Bleeding during Thermal Ablation of Liver Cancer |
| title_fullStr | Contrast-enhanced Ultrasound for Evaluation of Active Needle Tract Bleeding during Thermal Ablation of Liver Cancer |
| title_full_unstemmed | Contrast-enhanced Ultrasound for Evaluation of Active Needle Tract Bleeding during Thermal Ablation of Liver Cancer |
| title_short | Contrast-enhanced Ultrasound for Evaluation of Active Needle Tract Bleeding during Thermal Ablation of Liver Cancer |
| title_sort | contrast enhanced ultrasound for evaluation of active needle tract bleeding during thermal ablation of liver cancer |
| topic | |contrast-enhanced ultrasound|ablation techniques|liver cancer|haemorrhage |
| url | http://www.journaladvancedultrasound.com:81/fileup/2576-2516/PDF/1659941738529-763204809.pdf |
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