Does endoscopic ultrasound-guided fine needle biopsy using a Franseen needle really offer high diagnostic accuracy? A propensity-matched analysis
Background and study aims This study aimed to investigate the diagnostic accuracy and utility of endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) performed using a Franseen needle on solid pancreatic lesions. Patients and methods This study included 132 consecutive lesions sample...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Georg Thieme Verlag KG
2019-10-01
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| Series: | Endoscopy International Open |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/a-0957-3005 |
| _version_ | 1818514350742175744 |
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| author | Akashi Fujita Shomei Ryozawa Masafumi Mizuide Ryuichiro Araki Koji Nagata Yuki Tanisaka Maiko Harada Tomoya Ogawa Tomoaki Tashima Kouichi Nonaka |
| author_facet | Akashi Fujita Shomei Ryozawa Masafumi Mizuide Ryuichiro Araki Koji Nagata Yuki Tanisaka Maiko Harada Tomoya Ogawa Tomoaki Tashima Kouichi Nonaka |
| author_sort | Akashi Fujita |
| collection | DOAJ |
| description | Background and study aims This study aimed to investigate the diagnostic accuracy and utility of endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) performed using a Franseen needle on solid pancreatic lesions.
Patients and methods This study included 132 consecutive lesions sampled by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) using a 22-G conventional needle and 95 consecutive lesions evaluated by EUS-FNB using a 22-G Franseen needle to evaluate solid pancreatic lesions at our medical center between July 2013 and November 2018. We used propensity-matched analysis with adjustment for confounders. Patient data were analyzed retrospectively.
Results Diagnostic accuracy was higher in the Franseen needle group (Group F; 91.6 %, 87 /95) than in the conventional needle group (Group C; 86.3 %, 82 /95), showing no significant difference (P = 0.36). In Group F, diagnostic accuracies for pancreatic head lesions and lesions sampled by transduodenal puncture were 98.0 % (48/49) and 97.9 % (46/47), respectively. These values were significantly higher than values in Group C (P = 0.013, 0.01). Group F displayed a significantly lower number of punctures. In terms of differentiating benign from malignant lesions, Group C showed 85.1 % sensitivity (74/87), 100 % specificity (8/8), 100 % positive predictive value (74/74), and 38.1 % negative predictive value (8/21), compared to values of 90.1 % (73/81), 100 % (14/14), 100 % (73/73), and 63.6 % (14/22), respectively, in Group F. Sensitivity and negative predictive value were better in Group F.
Conclusions Franseen needles for EUS-FNB of solid pancreatic lesions offer similar puncture performance at different lesion sites while requiring fewer punctures than conventional needles. |
| first_indexed | 2024-12-11T00:14:34Z |
| format | Article |
| id | doaj.art-8647b27055f746adbb2489e2fd6581f8 |
| institution | Directory Open Access Journal |
| issn | 2364-3722 2196-9736 |
| language | English |
| last_indexed | 2024-12-11T00:14:34Z |
| publishDate | 2019-10-01 |
| publisher | Georg Thieme Verlag KG |
| record_format | Article |
| series | Endoscopy International Open |
| spelling | doaj.art-8647b27055f746adbb2489e2fd6581f82022-12-22T01:28:00ZengGeorg Thieme Verlag KGEndoscopy International Open2364-37222196-97362019-10-010711E1327E133210.1055/a-0957-3005Does endoscopic ultrasound-guided fine needle biopsy using a Franseen needle really offer high diagnostic accuracy? A propensity-matched analysisAkashi Fujita0Shomei Ryozawa1Masafumi Mizuide2Ryuichiro Araki3Koji Nagata4Yuki Tanisaka5Maiko Harada6Tomoya Ogawa7Tomoaki Tashima8Kouichi Nonaka9Department of Gastroenterology, Saitama Medical University International Medical Center, Saitama, JapanDepartment of Gastroenterology, Saitama Medical University International Medical Center, Saitama, JapanDepartment of Gastroenterology, Saitama Medical University International Medical Center, Saitama, JapanCommunity Health Science Center, Saitama Medical University, Saitama, JapanDepartment of Pathology, Saitama Medical University International Medical Center, Saitama, JapanDepartment of Gastroenterology, Saitama Medical University International Medical Center, Saitama, JapanDepartment of Gastroenterology, Saitama Medical University International Medical Center, Saitama, JapanDepartment of Gastroenterology, Saitama Medical University International Medical Center, Saitama, JapanDepartment of Gastroenterology, Saitama Medical University International Medical Center, Saitama, JapanDepartment of Gastroenterology, Saitama Medical University International Medical Center, Saitama, JapanBackground and study aims This study aimed to investigate the diagnostic accuracy and utility of endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) performed using a Franseen needle on solid pancreatic lesions. Patients and methods This study included 132 consecutive lesions sampled by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) using a 22-G conventional needle and 95 consecutive lesions evaluated by EUS-FNB using a 22-G Franseen needle to evaluate solid pancreatic lesions at our medical center between July 2013 and November 2018. We used propensity-matched analysis with adjustment for confounders. Patient data were analyzed retrospectively. Results Diagnostic accuracy was higher in the Franseen needle group (Group F; 91.6 %, 87 /95) than in the conventional needle group (Group C; 86.3 %, 82 /95), showing no significant difference (P = 0.36). In Group F, diagnostic accuracies for pancreatic head lesions and lesions sampled by transduodenal puncture were 98.0 % (48/49) and 97.9 % (46/47), respectively. These values were significantly higher than values in Group C (P = 0.013, 0.01). Group F displayed a significantly lower number of punctures. In terms of differentiating benign from malignant lesions, Group C showed 85.1 % sensitivity (74/87), 100 % specificity (8/8), 100 % positive predictive value (74/74), and 38.1 % negative predictive value (8/21), compared to values of 90.1 % (73/81), 100 % (14/14), 100 % (73/73), and 63.6 % (14/22), respectively, in Group F. Sensitivity and negative predictive value were better in Group F. Conclusions Franseen needles for EUS-FNB of solid pancreatic lesions offer similar puncture performance at different lesion sites while requiring fewer punctures than conventional needles.http://www.thieme-connect.de/DOI/DOI?10.1055/a-0957-3005 |
| spellingShingle | Akashi Fujita Shomei Ryozawa Masafumi Mizuide Ryuichiro Araki Koji Nagata Yuki Tanisaka Maiko Harada Tomoya Ogawa Tomoaki Tashima Kouichi Nonaka Does endoscopic ultrasound-guided fine needle biopsy using a Franseen needle really offer high diagnostic accuracy? A propensity-matched analysis Endoscopy International Open |
| title | Does endoscopic ultrasound-guided fine needle biopsy using a Franseen needle really offer high diagnostic accuracy? A propensity-matched analysis |
| title_full | Does endoscopic ultrasound-guided fine needle biopsy using a Franseen needle really offer high diagnostic accuracy? A propensity-matched analysis |
| title_fullStr | Does endoscopic ultrasound-guided fine needle biopsy using a Franseen needle really offer high diagnostic accuracy? A propensity-matched analysis |
| title_full_unstemmed | Does endoscopic ultrasound-guided fine needle biopsy using a Franseen needle really offer high diagnostic accuracy? A propensity-matched analysis |
| title_short | Does endoscopic ultrasound-guided fine needle biopsy using a Franseen needle really offer high diagnostic accuracy? A propensity-matched analysis |
| title_sort | does endoscopic ultrasound guided fine needle biopsy using a franseen needle really offer high diagnostic accuracy a propensity matched analysis |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/a-0957-3005 |
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