Preoperative Endovascular Embolization of Glomus Jugulare Tumors: A Retrospective Case Series of 22 Embolizations in 20 Patients and Literature Review
Objective Glomus jugulare tumors, or tympanojugular paragangliomas, are rare, highly vascularized skull base tumors originated from paraganglion cells of the neural crest. With nonabsorbable embolic agents, embolization combined with surgery has become the norm. The authors assess the profile and ou...
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações Ltda.
2022-03-01
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| Series: | Brazilian Neurosurgery |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1739270 |
| _version_ | 1818918546442289152 |
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| author | Matheus Kahakura Franco Pedro André Giacomelli Leal Ricardo Ramina Murilo Sousa de Meneses |
| author_facet | Matheus Kahakura Franco Pedro André Giacomelli Leal Ricardo Ramina Murilo Sousa de Meneses |
| author_sort | Matheus Kahakura Franco Pedro |
| collection | DOAJ |
| description | Objective Glomus jugulare tumors, or tympanojugular paragangliomas, are rare, highly vascularized skull base tumors originated from paraganglion cells of the neural crest. With nonabsorbable embolic agents, embolization combined with surgery has become the norm. The authors assess the profile and outcomes of patients submitted to preoperative embolization in a Brazilian tertiary care hospital.
Methods The present study is a single-center, retrospective analysis; between January 2008 and December 2019, 22 embolizations were performed in 20 patients in a preoperative character, and their medical records were analyzed for the present case series.
Results Hearing loss was the most common symptom, present in 50% of the patients, while 40% had tinnitus, 30% had dysphagia, 25% had facial paralysis, 20% had hoarseness, and 10% had diplopia. In 7 out of 22 embolization procedures (31%) more than a single embolic agent was used; Gelfoam (Pfizer, New York, NY, USA) was used in 18 procedures (81%), in 12 of which as the single agent, followed by Embosphere (Merit Medical, South Jordan, UT, USA) (31%), Onyx (Medtronic, Minneapolis, MN, USA) (9%), and polyvynil alcohol (PVA) and Bead Block (Boston Scientific, Marlborough, MA, USA) in 4,5% each. The most common vessel involved was the ascending pharyngeal artery, involved in 90% of the patients, followed by the posterior auricular artery in 15%, the internal maxillary artery or the occipital artery in 10% each, and the superficial temporal or the lingual arteries, with 6% each. Only one patient had involvement of the internal carotid artery. No complications from embolization were recorded.
Conclusions Preoperative embolization of glomus tumors is safe and reduces surgical time and complications, due to the decrease in size and bleeding. |
| first_indexed | 2024-12-20T00:51:41Z |
| format | Article |
| id | doaj.art-8648df3d25ff4dad8731672e7c75cc4c |
| institution | Directory Open Access Journal |
| issn | 0103-5355 2359-5922 |
| language | English |
| last_indexed | 2024-12-20T00:51:41Z |
| publishDate | 2022-03-01 |
| publisher | Thieme Revinter Publicações Ltda. |
| record_format | Article |
| series | Brazilian Neurosurgery |
| spelling | doaj.art-8648df3d25ff4dad8731672e7c75cc4c2022-12-21T19:59:13ZengThieme Revinter Publicações Ltda.Brazilian Neurosurgery0103-53552359-59222022-03-014101e26e3410.1055/s-0041-1739270Preoperative Endovascular Embolization of Glomus Jugulare Tumors: A Retrospective Case Series of 22 Embolizations in 20 Patients and Literature ReviewMatheus Kahakura Franco Pedro0André Giacomelli Leal1Ricardo Ramina2Murilo Sousa de Meneses3Department of Neurology, Neurological Institute of Curitiba, Curitiba, PR, BrazilDepartment of Endovascular Neurosurgery and Interventional Neuroradiology, Neurological Institute of Curitiba, Curitiba, PR, BrazilDepartment of Vascular Neurosurgery, Neurological Institute of Curitiba, Curitiba, PR, BrazilDepartment of Endovascular Neurosurgery and Interventional Neuroradiology, Neurological Institute of Curitiba, Curitiba, PR, BrazilObjective Glomus jugulare tumors, or tympanojugular paragangliomas, are rare, highly vascularized skull base tumors originated from paraganglion cells of the neural crest. With nonabsorbable embolic agents, embolization combined with surgery has become the norm. The authors assess the profile and outcomes of patients submitted to preoperative embolization in a Brazilian tertiary care hospital. Methods The present study is a single-center, retrospective analysis; between January 2008 and December 2019, 22 embolizations were performed in 20 patients in a preoperative character, and their medical records were analyzed for the present case series. Results Hearing loss was the most common symptom, present in 50% of the patients, while 40% had tinnitus, 30% had dysphagia, 25% had facial paralysis, 20% had hoarseness, and 10% had diplopia. In 7 out of 22 embolization procedures (31%) more than a single embolic agent was used; Gelfoam (Pfizer, New York, NY, USA) was used in 18 procedures (81%), in 12 of which as the single agent, followed by Embosphere (Merit Medical, South Jordan, UT, USA) (31%), Onyx (Medtronic, Minneapolis, MN, USA) (9%), and polyvynil alcohol (PVA) and Bead Block (Boston Scientific, Marlborough, MA, USA) in 4,5% each. The most common vessel involved was the ascending pharyngeal artery, involved in 90% of the patients, followed by the posterior auricular artery in 15%, the internal maxillary artery or the occipital artery in 10% each, and the superficial temporal or the lingual arteries, with 6% each. Only one patient had involvement of the internal carotid artery. No complications from embolization were recorded. Conclusions Preoperative embolization of glomus tumors is safe and reduces surgical time and complications, due to the decrease in size and bleeding.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1739270endovascular proceduresglomus jugularetherapeutic embolization |
| spellingShingle | Matheus Kahakura Franco Pedro André Giacomelli Leal Ricardo Ramina Murilo Sousa de Meneses Preoperative Endovascular Embolization of Glomus Jugulare Tumors: A Retrospective Case Series of 22 Embolizations in 20 Patients and Literature Review Brazilian Neurosurgery endovascular procedures glomus jugulare therapeutic embolization |
| title | Preoperative Endovascular Embolization of Glomus Jugulare Tumors: A Retrospective Case Series of 22 Embolizations in 20 Patients and Literature Review |
| title_full | Preoperative Endovascular Embolization of Glomus Jugulare Tumors: A Retrospective Case Series of 22 Embolizations in 20 Patients and Literature Review |
| title_fullStr | Preoperative Endovascular Embolization of Glomus Jugulare Tumors: A Retrospective Case Series of 22 Embolizations in 20 Patients and Literature Review |
| title_full_unstemmed | Preoperative Endovascular Embolization of Glomus Jugulare Tumors: A Retrospective Case Series of 22 Embolizations in 20 Patients and Literature Review |
| title_short | Preoperative Endovascular Embolization of Glomus Jugulare Tumors: A Retrospective Case Series of 22 Embolizations in 20 Patients and Literature Review |
| title_sort | preoperative endovascular embolization of glomus jugulare tumors a retrospective case series of 22 embolizations in 20 patients and literature review |
| topic | endovascular procedures glomus jugulare therapeutic embolization |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1739270 |
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