Sugammadex-associated asystole in young obese patient: Case report
Sugammadex is a neuromuscular blocking (NMB) reversal agent that has quickly become popular among anesthesia providers since its FDA approval in 2015 due to its favorable properties. There are rare but significant and increasingly reported adverse cardiac events, including symptomatic bradycardia, a...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-09-01
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| Series: | Oral and Maxillofacial Surgery Cases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S221454192200030X |
| _version_ | 1818516369332764672 |
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| author | Steven J. Lohmeier David B. Powers |
| author_facet | Steven J. Lohmeier David B. Powers |
| author_sort | Steven J. Lohmeier |
| collection | DOAJ |
| description | Sugammadex is a neuromuscular blocking (NMB) reversal agent that has quickly become popular among anesthesia providers since its FDA approval in 2015 due to its favorable properties. There are rare but significant and increasingly reported adverse cardiac events, including symptomatic bradycardia, asystole, cardiac arrest, and death. Since its introduction into the United States (US) market, there have been ten reported cases of asystole and cardiac arrest within minutes of sugammadex administration. Some incidents required cardiopulmonary resuscitation (CPR) and prolonged treatment in the Intensive Care Unit (ICU) for successful management. We present the youngest known case of sugammadex-associated asystole in a non-cardiac patient. Further investigation is warranted to understand better both the patient-related factors and drug administration techniques involved in Sugammadex-associated cardiovascular compromise to improve clinical decision-making for anesthesia providers. |
| first_indexed | 2024-12-11T00:41:08Z |
| format | Article |
| id | doaj.art-864a3e250ea148368a78474b31f66f4d |
| institution | Directory Open Access Journal |
| issn | 2214-5419 |
| language | English |
| last_indexed | 2024-12-11T00:41:08Z |
| publishDate | 2022-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Oral and Maxillofacial Surgery Cases |
| spelling | doaj.art-864a3e250ea148368a78474b31f66f4d2022-12-22T01:26:55ZengElsevierOral and Maxillofacial Surgery Cases2214-54192022-09-0183100271Sugammadex-associated asystole in young obese patient: Case reportSteven J. Lohmeier0David B. Powers1Division of Plastic, Maxillofacial & Oral Surgery, Duke University Hospital, Durham, NC, USA; US Air Force Dental Corps, USADivision of Plastic, Maxillofacial & Oral Surgery, Duke University Hospital, Durham, NC, USA; Corresponding author. Division of Plastic, Maxillofacial & Oral Surgery, Duke University Hospital, DUMC 3974 — Room 110 Baker House, 200 Trent Drive at Erwin Road, Durham, NC, 27710, USA.Sugammadex is a neuromuscular blocking (NMB) reversal agent that has quickly become popular among anesthesia providers since its FDA approval in 2015 due to its favorable properties. There are rare but significant and increasingly reported adverse cardiac events, including symptomatic bradycardia, asystole, cardiac arrest, and death. Since its introduction into the United States (US) market, there have been ten reported cases of asystole and cardiac arrest within minutes of sugammadex administration. Some incidents required cardiopulmonary resuscitation (CPR) and prolonged treatment in the Intensive Care Unit (ICU) for successful management. We present the youngest known case of sugammadex-associated asystole in a non-cardiac patient. Further investigation is warranted to understand better both the patient-related factors and drug administration techniques involved in Sugammadex-associated cardiovascular compromise to improve clinical decision-making for anesthesia providers.http://www.sciencedirect.com/science/article/pii/S221454192200030XSugammadexObesityGeneral anesthesiaAsystoleNeuromuscular blockade |
| spellingShingle | Steven J. Lohmeier David B. Powers Sugammadex-associated asystole in young obese patient: Case report Oral and Maxillofacial Surgery Cases Sugammadex Obesity General anesthesia Asystole Neuromuscular blockade |
| title | Sugammadex-associated asystole in young obese patient: Case report |
| title_full | Sugammadex-associated asystole in young obese patient: Case report |
| title_fullStr | Sugammadex-associated asystole in young obese patient: Case report |
| title_full_unstemmed | Sugammadex-associated asystole in young obese patient: Case report |
| title_short | Sugammadex-associated asystole in young obese patient: Case report |
| title_sort | sugammadex associated asystole in young obese patient case report |
| topic | Sugammadex Obesity General anesthesia Asystole Neuromuscular blockade |
| url | http://www.sciencedirect.com/science/article/pii/S221454192200030X |
| work_keys_str_mv | AT stevenjlohmeier sugammadexassociatedasystoleinyoungobesepatientcasereport AT davidbpowers sugammadexassociatedasystoleinyoungobesepatientcasereport |