Silver Nimesulide Complex in Bacterial Cellulose Membranes as an Innovative Therapeutic Method for Topical Treatment of Skin Squamous Cell Carcinoma

Silver Nimesulide Complex in Bacterial Cellulose Membranes as an Innovative Therapeutic Method for Topical Treatment of Skin Squamous Cell Carcinoma

Oxidative stress and inflammation act on skin squamous cell carcinoma (SSCC) development and progression. Curative therapy for SSCC patients is mainly based on surgical resection, which can cause various sequelae. Silver ions have in vitro activities over tumor cells, while nimesulide has antioxidan...

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Bibliographic Details
Main Authors: Tuany Zambroti Candido, Raphael Enoque Ferraz de Paiva, Mariana Cecchetto Figueiredo, Lilian de Oliveira Coser, Silmara Cristina Lazarini Frajácomo, Camilla Abbehausen, Izilda Aparecida Cardinalli, Wilton Rogerio Lustri, João Ernesto Carvalho, Ana Lucia Tasca Gois Ruiz, Pedro Paulo Corbi, Carmen Silvia Passos Lima
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Pharmaceutics
Subjects:
skin carcinoma
silver
nimesulide
bacterial cellulose
topical administration
antitumor activity
Online Access:https://www.mdpi.com/1999-4923/14/2/462

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