Automated generation of genome-scale metabolic draft reconstructions based on KEGG

Abstract Background Constraint-based modeling is a widely used and powerful methodology to assess the metabolic phenotypes and capabilities of an organism. The starting point and cornerstone of all such modeling is a genome-scale metabolic network reconstruction. The creation, further development, a...

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Bibliographic Details
Main Authors: Emil Karlsen, Christian Schulz, Eivind Almaas
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-018-2472-z