IL-33 and Superantigenic Activation of Human Lung Mast Cells Induce the Release of Angiogenic and Lymphangiogenic Factors

IL-33 and Superantigenic Activation of Human Lung Mast Cells Induce the Release of Angiogenic and Lymphangiogenic Factors

Human lung mast cells (HLMCs) express the high-affinity receptor FcεRI for IgE and are strategically located in different compartments of human lung, where they play a role in several inflammatory disorders and cancer. Immunoglobulin superantigens (e.g., protein A of <i>Staphylococcus aureus&l...

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Bibliographic Details
Main Authors: Leonardo Cristinziano, Remo Poto, Gjada Criscuolo, Anne Lise Ferrara, Maria Rosaria Galdiero, Luca Modestino, Stefania Loffredo, Amato de Paulis, Gianni Marone, Giuseppe Spadaro, Gilda Varricchi
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cells
Subjects:
allergy
asthma
histamine
IL-33
mast cell
protein A
Online Access:https://www.mdpi.com/2073-4409/10/1/145

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