Enhancing Degradation Resistance of Biomedical Mg-6Zn-0.5Zr Alloy by the Incorporation of Nanodiamond
The Mg-6Zn-0.5Zr (ZK60) alloy has attracted extensive attention as one of the hopeful biomedical material candidates for bone implant applications on account of its unique degradability, favorable biocompatibility as well as mechanical compatibility. Nevertheless, the rapid degradation rate in the b...
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MDPI AG
2022-09-01
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| Online Access: | https://www.mdpi.com/1996-1944/15/19/6707 |
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| author | Long Liu Shun He Zhiming Guo Jian Li Mingchun Zhao Yiping Wu |
| author_facet | Long Liu Shun He Zhiming Guo Jian Li Mingchun Zhao Yiping Wu |
| author_sort | Long Liu |
| collection | DOAJ |
| description | The Mg-6Zn-0.5Zr (ZK60) alloy has attracted extensive attention as one of the hopeful biomedical material candidates for bone implant applications on account of its unique degradability, favorable biocompatibility as well as mechanical compatibility. Nevertheless, the rapid degradation rate in the biological environment is the major hurdle for its clinical application in the field of bone implants. In this study, nanodiamond (ND) was incorporated into ZK60 alloy via selective laser melting technology to enhance its degradation resistance. The results showed that compared with selective laser-melted ZK60 (SLMed ZK60), the selective laser-melted ZK60 with 6 wt.% ND (SLMed ZK60−6ND) possessed the better degradation resistance with the lower degradation rate of 0.5 ± 0.1 mm/year. The enhancement of the degradation resistance was attributed to the fact that ND could promote the deposition of apatite and build up a dense and insoluble protective layer through the dissociation of the carboxyl groups on the ND surface, which could effectively hinder the further degradation of the Mg matrix. Meanwhile, the compressive strength and hardness were improved mainly due to grain refinement strengthening and ND dispersion strengthening. In addition, the SLMed ZK60−6ND possessed good cytocompatibility. These results suggested that the SLMed ZK60−6ND, with enhanced degradation resistance, improved mechanical properties, and good cytocompatibility, was an excellent biomedical material candidate for bone implant applications. |
| first_indexed | 2024-03-09T21:31:32Z |
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| id | doaj.art-86513f3ef07e4ee49d1e29a927127376 |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-09T21:31:32Z |
| publishDate | 2022-09-01 |
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| spelling | doaj.art-86513f3ef07e4ee49d1e29a9271273762023-11-23T20:55:22ZengMDPI AGMaterials1996-19442022-09-011519670710.3390/ma15196707Enhancing Degradation Resistance of Biomedical Mg-6Zn-0.5Zr Alloy by the Incorporation of NanodiamondLong Liu0Shun He1Zhiming Guo2Jian Li3Mingchun Zhao4Yiping Wu5Department of Mechanical and Electrical Engineering, Changsha University, Changsha 410003, ChinaDepartment of Mechanical and Electrical Engineering, Changsha University, Changsha 410003, ChinaDepartment of Mechanical and Electrical Engineering, Changsha University, Changsha 410003, ChinaDepartment of Mechanical and Electrical Engineering, Changsha University, Changsha 410003, ChinaSchool of Materials Science and Engineering, Central South University, Changsha 410083, ChinaDepartment of Mechanical and Electrical Engineering, Changsha University, Changsha 410003, ChinaThe Mg-6Zn-0.5Zr (ZK60) alloy has attracted extensive attention as one of the hopeful biomedical material candidates for bone implant applications on account of its unique degradability, favorable biocompatibility as well as mechanical compatibility. Nevertheless, the rapid degradation rate in the biological environment is the major hurdle for its clinical application in the field of bone implants. In this study, nanodiamond (ND) was incorporated into ZK60 alloy via selective laser melting technology to enhance its degradation resistance. The results showed that compared with selective laser-melted ZK60 (SLMed ZK60), the selective laser-melted ZK60 with 6 wt.% ND (SLMed ZK60−6ND) possessed the better degradation resistance with the lower degradation rate of 0.5 ± 0.1 mm/year. The enhancement of the degradation resistance was attributed to the fact that ND could promote the deposition of apatite and build up a dense and insoluble protective layer through the dissociation of the carboxyl groups on the ND surface, which could effectively hinder the further degradation of the Mg matrix. Meanwhile, the compressive strength and hardness were improved mainly due to grain refinement strengthening and ND dispersion strengthening. In addition, the SLMed ZK60−6ND possessed good cytocompatibility. These results suggested that the SLMed ZK60−6ND, with enhanced degradation resistance, improved mechanical properties, and good cytocompatibility, was an excellent biomedical material candidate for bone implant applications.https://www.mdpi.com/1996-1944/15/19/6707selective laser meltingMg alloysnanodiamondapatite layerdegradation resistance |
| spellingShingle | Long Liu Shun He Zhiming Guo Jian Li Mingchun Zhao Yiping Wu Enhancing Degradation Resistance of Biomedical Mg-6Zn-0.5Zr Alloy by the Incorporation of Nanodiamond Materials selective laser melting Mg alloys nanodiamond apatite layer degradation resistance |
| title | Enhancing Degradation Resistance of Biomedical Mg-6Zn-0.5Zr Alloy by the Incorporation of Nanodiamond |
| title_full | Enhancing Degradation Resistance of Biomedical Mg-6Zn-0.5Zr Alloy by the Incorporation of Nanodiamond |
| title_fullStr | Enhancing Degradation Resistance of Biomedical Mg-6Zn-0.5Zr Alloy by the Incorporation of Nanodiamond |
| title_full_unstemmed | Enhancing Degradation Resistance of Biomedical Mg-6Zn-0.5Zr Alloy by the Incorporation of Nanodiamond |
| title_short | Enhancing Degradation Resistance of Biomedical Mg-6Zn-0.5Zr Alloy by the Incorporation of Nanodiamond |
| title_sort | enhancing degradation resistance of biomedical mg 6zn 0 5zr alloy by the incorporation of nanodiamond |
| topic | selective laser melting Mg alloys nanodiamond apatite layer degradation resistance |
| url | https://www.mdpi.com/1996-1944/15/19/6707 |
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