Corneal Epithelium Asymmetry in Children With Atopy: The Effect of Hand Dominance
Tomás Loureiro,1 Sandra Rodrigues-Barros,1 Ana Rita Carreira,1 Filipe Gouveia-Moraes,1 Pedro Carreira,1 Ana Vide Escada,1 Paul Campos,1 Inês Machado,1 Nuno Campos,1 Timothy J Archer,2 Dan Z Reinstein,2 Renato Ambrósio Jr3 1Ophthalmology Department, Hospital Garcia de Orta, Almada, Portugal; 2London...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2022-08-01
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| Series: | Clinical Ophthalmology |
| Subjects: | |
| Online Access: | https://www.dovepress.com/corneal-epithelium-asymmetry-in-children-with-atopy-the-effect-of-hand-peer-reviewed-fulltext-article-OPTH |
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| author | Loureiro T Rodrigues-Barros S Carreira AR Gouveia-Moraes F Carreira P Vide Escada A Campos P Machado I Campos N Archer TJ Reinstein DZ Ambrósio R Jr |
| author_facet | Loureiro T Rodrigues-Barros S Carreira AR Gouveia-Moraes F Carreira P Vide Escada A Campos P Machado I Campos N Archer TJ Reinstein DZ Ambrósio R Jr |
| author_sort | Loureiro T |
| collection | DOAJ |
| description | Tomás Loureiro,1 Sandra Rodrigues-Barros,1 Ana Rita Carreira,1 Filipe Gouveia-Moraes,1 Pedro Carreira,1 Ana Vide Escada,1 Paul Campos,1 Inês Machado,1 Nuno Campos,1 Timothy J Archer,2 Dan Z Reinstein,2 Renato Ambrósio Jr3 1Ophthalmology Department, Hospital Garcia de Orta, Almada, Portugal; 2London Vision Clinic, London, UK; 3Federal University of the State of Rio de Janeiro, Rio de Janeiro, BrazilCorrespondence: Tomás Loureiro, Ophthalmology Department, Hospital Garcia de Orta, Avenida Torrado da Silva, Almada, 2805-267, Portugal, Tel +35 1 913 513 175, Email loureiro.tomas@gmail.comPurpose: To evaluate the effect of eye rubbing on the epithelial thickness profile in tomographically normal corneas by AS-OCT and to compare right and left eyes in right-handed children.Methods: Thirty right-handed boys (mean age 11.2 years) with ocular allergy and history of eye rubbing were evaluated using Scheimpflug (Pentacam HR, Oculus Wetzlar, Germany) and anterior segment optical coherence tomography. Epithelial thickness (ET) and full corneal thickness (CT) parameters were compared between right and left eyes with a non-parametric Mann–Whitney test. A p-value lower than 0.05 was considered for statistical significance.Results: No eyes had topometric nor tomographic criteria for keratoconus. The min-max ET was lower in right eyes (− 2.8 μm vs − 3.5; p = 0.02). The difference between inferior and superior (I-S) octants was lower in right eyes (1.1 μm vs 1.9 μm; p = 0.03) as a result of inferotemporal thinning. The highest ET difference was registered between nasal and temporal octants and was more pronounced in the right eyes (2 μm vs 3.1 μm; p < 0.001).Conclusion: AS-OCT analyses reveal different epithelial thickness patterns between the eyes in young atopic patients, likely eye rubbers. Inferior and temporal epithelial thickness seem to be more affected by thinning in the eye on the side of the dominant hand.Keywords: eye rubbing, keratoconus, epithelial thickness, AS-OCT, pediatrics |
| first_indexed | 2024-04-11T22:17:24Z |
| format | Article |
| id | doaj.art-8654780d0eef4c8daf8b7f41beaf822d |
| institution | Directory Open Access Journal |
| issn | 1177-5483 |
| language | English |
| last_indexed | 2024-04-11T22:17:24Z |
| publishDate | 2022-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Ophthalmology |
| spelling | doaj.art-8654780d0eef4c8daf8b7f41beaf822d2022-12-22T04:00:19ZengDove Medical PressClinical Ophthalmology1177-54832022-08-01Volume 162453246177152Corneal Epithelium Asymmetry in Children With Atopy: The Effect of Hand DominanceLoureiro TRodrigues-Barros SCarreira ARGouveia-Moraes FCarreira PVide Escada ACampos PMachado ICampos NArcher TJReinstein DZAmbrósio R JrTomás Loureiro,1 Sandra Rodrigues-Barros,1 Ana Rita Carreira,1 Filipe Gouveia-Moraes,1 Pedro Carreira,1 Ana Vide Escada,1 Paul Campos,1 Inês Machado,1 Nuno Campos,1 Timothy J Archer,2 Dan Z Reinstein,2 Renato Ambrósio Jr3 1Ophthalmology Department, Hospital Garcia de Orta, Almada, Portugal; 2London Vision Clinic, London, UK; 3Federal University of the State of Rio de Janeiro, Rio de Janeiro, BrazilCorrespondence: Tomás Loureiro, Ophthalmology Department, Hospital Garcia de Orta, Avenida Torrado da Silva, Almada, 2805-267, Portugal, Tel +35 1 913 513 175, Email loureiro.tomas@gmail.comPurpose: To evaluate the effect of eye rubbing on the epithelial thickness profile in tomographically normal corneas by AS-OCT and to compare right and left eyes in right-handed children.Methods: Thirty right-handed boys (mean age 11.2 years) with ocular allergy and history of eye rubbing were evaluated using Scheimpflug (Pentacam HR, Oculus Wetzlar, Germany) and anterior segment optical coherence tomography. Epithelial thickness (ET) and full corneal thickness (CT) parameters were compared between right and left eyes with a non-parametric Mann–Whitney test. A p-value lower than 0.05 was considered for statistical significance.Results: No eyes had topometric nor tomographic criteria for keratoconus. The min-max ET was lower in right eyes (− 2.8 μm vs − 3.5; p = 0.02). The difference between inferior and superior (I-S) octants was lower in right eyes (1.1 μm vs 1.9 μm; p = 0.03) as a result of inferotemporal thinning. The highest ET difference was registered between nasal and temporal octants and was more pronounced in the right eyes (2 μm vs 3.1 μm; p < 0.001).Conclusion: AS-OCT analyses reveal different epithelial thickness patterns between the eyes in young atopic patients, likely eye rubbers. Inferior and temporal epithelial thickness seem to be more affected by thinning in the eye on the side of the dominant hand.Keywords: eye rubbing, keratoconus, epithelial thickness, AS-OCT, pediatricshttps://www.dovepress.com/corneal-epithelium-asymmetry-in-children-with-atopy-the-effect-of-hand-peer-reviewed-fulltext-article-OPTHeye rubbingkeratoconusepithelial thicknessas-octpediatrics |
| spellingShingle | Loureiro T Rodrigues-Barros S Carreira AR Gouveia-Moraes F Carreira P Vide Escada A Campos P Machado I Campos N Archer TJ Reinstein DZ Ambrósio R Jr Corneal Epithelium Asymmetry in Children With Atopy: The Effect of Hand Dominance Clinical Ophthalmology eye rubbing keratoconus epithelial thickness as-oct pediatrics |
| title | Corneal Epithelium Asymmetry in Children With Atopy: The Effect of Hand Dominance |
| title_full | Corneal Epithelium Asymmetry in Children With Atopy: The Effect of Hand Dominance |
| title_fullStr | Corneal Epithelium Asymmetry in Children With Atopy: The Effect of Hand Dominance |
| title_full_unstemmed | Corneal Epithelium Asymmetry in Children With Atopy: The Effect of Hand Dominance |
| title_short | Corneal Epithelium Asymmetry in Children With Atopy: The Effect of Hand Dominance |
| title_sort | corneal epithelium asymmetry in children with atopy the effect of hand dominance |
| topic | eye rubbing keratoconus epithelial thickness as-oct pediatrics |
| url | https://www.dovepress.com/corneal-epithelium-asymmetry-in-children-with-atopy-the-effect-of-hand-peer-reviewed-fulltext-article-OPTH |
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