From lifetime to evolution: timescales of human gut microbiota adaptation
Human beings harbor gut microbial communities that are essential to preserve human health. Molded by the human genome, the gut microbiota is an adaptive component of the human superorganisms that allows host adaptation at different timescales, optimizing host physiology from daily life to lifespan s...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2014-11-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00587/full |
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| author | Sara eQuercia Marco eCandela Cristina eGiuliani Silvia eTurroni Donata eLuiselli Simone eRampelli Patrizia eBrigidi Claudio eFranceschi Claudio eFranceschi Claudio eFranceschi Claudio eFranceschi Claudio eFranceschi Maria Giulia eBacalini Maria Giulia eBacalini Paolo eGaragnani Paolo eGaragnani Paolo eGaragnani Chiara ePirazzini Chiara ePirazzini |
| author_facet | Sara eQuercia Marco eCandela Cristina eGiuliani Silvia eTurroni Donata eLuiselli Simone eRampelli Patrizia eBrigidi Claudio eFranceschi Claudio eFranceschi Claudio eFranceschi Claudio eFranceschi Claudio eFranceschi Maria Giulia eBacalini Maria Giulia eBacalini Paolo eGaragnani Paolo eGaragnani Paolo eGaragnani Chiara ePirazzini Chiara ePirazzini |
| author_sort | Sara eQuercia |
| collection | DOAJ |
| description | Human beings harbor gut microbial communities that are essential to preserve human health. Molded by the human genome, the gut microbiota is an adaptive component of the human superorganisms that allows host adaptation at different timescales, optimizing host physiology from daily life to lifespan scales and human evolutionary history. The gut microbiota continuously changes from birth up to the most extreme limits of human life, reconfiguring its metagenomic layout in response to daily variations in diet or specific host physiological and immunological needs at different ages. On the other hand, the microbiota plasticity was strategic to face changes in lifestyle and dietary habits along the course of the recent evolutionary history, that has driven the passage from Paleolithic hunter-gathering societies to Neolithic agricultural farmers to modern Westernized societies. |
| first_indexed | 2024-12-23T19:53:28Z |
| format | Article |
| id | doaj.art-8655ef6c27f3493f98339fde85d742ea |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-12-23T19:53:28Z |
| publishDate | 2014-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-8655ef6c27f3493f98339fde85d742ea2022-12-21T17:33:18ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2014-11-01510.3389/fmicb.2014.0058796881From lifetime to evolution: timescales of human gut microbiota adaptationSara eQuercia0Marco eCandela1Cristina eGiuliani2Silvia eTurroni3Donata eLuiselli4Simone eRampelli5Patrizia eBrigidi6Claudio eFranceschi7Claudio eFranceschi8Claudio eFranceschi9Claudio eFranceschi10Claudio eFranceschi11Maria Giulia eBacalini12Maria Giulia eBacalini13Paolo eGaragnani14Paolo eGaragnani15Paolo eGaragnani16Chiara ePirazzini17Chiara ePirazzini18University of BolognaUniversity of BolognaUniversity of BolognaUniversity of BolognaUniversity of BolognaUniversity of BolognaUniversity of BolognaUniversity of BolognaUniversity of BolognaIGM-CNR Institute of Molecular Genetics, Unit of Bologna IORCNR, Institute of Organic Synthesis and Photoreactivity (ISOF)IRCSS, Institute of Neurological Sciences of BolognaUniversity of BolognaUniversity of BolognaUniversity of BolognaUniversity of BolognaCRBA, Center for Applied Biomedical Research, St. Orsola-Malpighi University HospitalUniversity of BolognaUniversity of BolognaHuman beings harbor gut microbial communities that are essential to preserve human health. Molded by the human genome, the gut microbiota is an adaptive component of the human superorganisms that allows host adaptation at different timescales, optimizing host physiology from daily life to lifespan scales and human evolutionary history. The gut microbiota continuously changes from birth up to the most extreme limits of human life, reconfiguring its metagenomic layout in response to daily variations in diet or specific host physiological and immunological needs at different ages. On the other hand, the microbiota plasticity was strategic to face changes in lifestyle and dietary habits along the course of the recent evolutionary history, that has driven the passage from Paleolithic hunter-gathering societies to Neolithic agricultural farmers to modern Westernized societies.http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00587/fullAgingDietGut MicrobiotaCo-Evolutionbiological adaptationEnvironmental stimuli |
| spellingShingle | Sara eQuercia Marco eCandela Cristina eGiuliani Silvia eTurroni Donata eLuiselli Simone eRampelli Patrizia eBrigidi Claudio eFranceschi Claudio eFranceschi Claudio eFranceschi Claudio eFranceschi Claudio eFranceschi Maria Giulia eBacalini Maria Giulia eBacalini Paolo eGaragnani Paolo eGaragnani Paolo eGaragnani Chiara ePirazzini Chiara ePirazzini From lifetime to evolution: timescales of human gut microbiota adaptation Frontiers in Microbiology Aging Diet Gut Microbiota Co-Evolution biological adaptation Environmental stimuli |
| title | From lifetime to evolution: timescales of human gut microbiota adaptation |
| title_full | From lifetime to evolution: timescales of human gut microbiota adaptation |
| title_fullStr | From lifetime to evolution: timescales of human gut microbiota adaptation |
| title_full_unstemmed | From lifetime to evolution: timescales of human gut microbiota adaptation |
| title_short | From lifetime to evolution: timescales of human gut microbiota adaptation |
| title_sort | from lifetime to evolution timescales of human gut microbiota adaptation |
| topic | Aging Diet Gut Microbiota Co-Evolution biological adaptation Environmental stimuli |
| url | http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00587/full |
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