Euphol from Euphorbia tirucalli Negatively Modulates TGF-β Responsiveness via TGF-β Receptor Segregation inside Membrane Rafts.

Euphol from Euphorbia tirucalli Negatively Modulates TGF-β Responsiveness via TGF-β Receptor Segregation inside Membrane Rafts.

Transforming growth factor-β (TGF-β) responsiveness in cultured cells can be modulated by TGF-β partitioning between lipid raft/caveolae- and clathrin-mediated endocytosis pathways. Lipid rafts are plasma membrane microdomains with an important role in cell survival signaling, and cholesterol is nec...

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Bibliographic Details
Main Authors: Chun-Lin Chen, Ying-Pin Chen, Ming-Wei Lin, Yaw-Bin Huang, Fang-Rong Chang, Tsai-Hui Duh, Deng-Chyang Wu, Wei-Chiang Wu, Yu-Chen Kao, Pei-Hua Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0140249&type=printable

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