Aging entails distinct requirements for Rb at maintaining adult neurogenesis
Cell cycle proteins play essential roles in regulating embryonic and adult neurogenesis in the mammalian brain. A key example is the Retinoblastoma protein (Rb) whose loss disrupts the whole neurogenic program during brain development, but only results in increased progenitor proliferation in the ad...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-01-01
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Series: | Aging Brain |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589958922000135 |