Aging entails distinct requirements for Rb at maintaining adult neurogenesis

Cell cycle proteins play essential roles in regulating embryonic and adult neurogenesis in the mammalian brain. A key example is the Retinoblastoma protein (Rb) whose loss disrupts the whole neurogenic program during brain development, but only results in increased progenitor proliferation in the ad...

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Bibliographic Details
Main Authors: Saad Omais, Rouba N. Hilal, Nour N. Halaby, Carine Jaafar, Noël Ghanem
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Aging Brain
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589958922000135

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