<i>Bacillus amyloliquefaciens</i>: Harnessing Its Potential for Industrial, Medical, and Agricultural Applications—A Comprehensive Review
<i>Bacillus amyloliquefaciens</i>, a Gram-positive bacterium, has emerged as a versatile microorganism with significant applications in various fields, including industry, medicine, and agriculture. This comprehensive review aims to provide an in-depth understanding of the characteristic...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/11/9/2215 |
| _version_ | 1797578746174111744 |
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| author | Imen Zalila-Kolsi Afif Ben-Mahmoud Ray Al-Barazie |
| author_facet | Imen Zalila-Kolsi Afif Ben-Mahmoud Ray Al-Barazie |
| author_sort | Imen Zalila-Kolsi |
| collection | DOAJ |
| description | <i>Bacillus amyloliquefaciens</i>, a Gram-positive bacterium, has emerged as a versatile microorganism with significant applications in various fields, including industry, medicine, and agriculture. This comprehensive review aims to provide an in-depth understanding of the characteristics, genetic tools, and metabolic capabilities of <i>B. amyloliquefaciens</i>, while highlighting its potential as a chassis cell for synthetic biology, metabolic engineering, and protein expression. We discuss the bacterium’s role in the production of chemicals, enzymes, and other industrial bioproducts, as well as its applications in medicine, such as combating infectious diseases and promoting gut health. In agriculture, <i>B. amyloliquefaciens</i> has demonstrated potential as a biofertilizer, biocontrol agent, and stress tolerance enhancer for various crops. Despite its numerous promising applications, <i>B. amyloliquefaciens</i> remains less studied than its Gram-negative counterpart, <i>Escherichia coli</i>. This review emphasizes the need for further research and development of advanced engineering techniques and genetic editing technologies tailored for <i>B. amyloliquefaciens</i>, ultimately unlocking its full potential in scientific and industrial contexts. |
| first_indexed | 2024-03-10T22:27:08Z |
| format | Article |
| id | doaj.art-8658e93f47e2481a9ab7cd2e4580d594 |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-10T22:27:08Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-8658e93f47e2481a9ab7cd2e4580d5942023-11-19T12:02:11ZengMDPI AGMicroorganisms2076-26072023-08-01119221510.3390/microorganisms11092215<i>Bacillus amyloliquefaciens</i>: Harnessing Its Potential for Industrial, Medical, and Agricultural Applications—A Comprehensive ReviewImen Zalila-Kolsi0Afif Ben-Mahmoud1Ray Al-Barazie2Faculty of Medical and Health Sciences, Liwa College, Abu Dhabi P.O. Box 41009, United Arab EmiratesNeurological Disorders Research Center, Qatar Biomedical Research Institute, Hamad Bin Khalifa University, Doha P.O. Box 34110, QatarFaculty of Medical and Health Sciences, Liwa College, Abu Dhabi P.O. Box 41009, United Arab Emirates<i>Bacillus amyloliquefaciens</i>, a Gram-positive bacterium, has emerged as a versatile microorganism with significant applications in various fields, including industry, medicine, and agriculture. This comprehensive review aims to provide an in-depth understanding of the characteristics, genetic tools, and metabolic capabilities of <i>B. amyloliquefaciens</i>, while highlighting its potential as a chassis cell for synthetic biology, metabolic engineering, and protein expression. We discuss the bacterium’s role in the production of chemicals, enzymes, and other industrial bioproducts, as well as its applications in medicine, such as combating infectious diseases and promoting gut health. In agriculture, <i>B. amyloliquefaciens</i> has demonstrated potential as a biofertilizer, biocontrol agent, and stress tolerance enhancer for various crops. Despite its numerous promising applications, <i>B. amyloliquefaciens</i> remains less studied than its Gram-negative counterpart, <i>Escherichia coli</i>. This review emphasizes the need for further research and development of advanced engineering techniques and genetic editing technologies tailored for <i>B. amyloliquefaciens</i>, ultimately unlocking its full potential in scientific and industrial contexts.https://www.mdpi.com/2076-2607/11/9/2215<i>Bacillus amyloliquefaciens</i>industrial applicationsmedical applicationsagricultural applicationsmetabolic engineering |
| spellingShingle | Imen Zalila-Kolsi Afif Ben-Mahmoud Ray Al-Barazie <i>Bacillus amyloliquefaciens</i>: Harnessing Its Potential for Industrial, Medical, and Agricultural Applications—A Comprehensive Review Microorganisms <i>Bacillus amyloliquefaciens</i> industrial applications medical applications agricultural applications metabolic engineering |
| title | <i>Bacillus amyloliquefaciens</i>: Harnessing Its Potential for Industrial, Medical, and Agricultural Applications—A Comprehensive Review |
| title_full | <i>Bacillus amyloliquefaciens</i>: Harnessing Its Potential for Industrial, Medical, and Agricultural Applications—A Comprehensive Review |
| title_fullStr | <i>Bacillus amyloliquefaciens</i>: Harnessing Its Potential for Industrial, Medical, and Agricultural Applications—A Comprehensive Review |
| title_full_unstemmed | <i>Bacillus amyloliquefaciens</i>: Harnessing Its Potential for Industrial, Medical, and Agricultural Applications—A Comprehensive Review |
| title_short | <i>Bacillus amyloliquefaciens</i>: Harnessing Its Potential for Industrial, Medical, and Agricultural Applications—A Comprehensive Review |
| title_sort | i bacillus amyloliquefaciens i harnessing its potential for industrial medical and agricultural applications a comprehensive review |
| topic | <i>Bacillus amyloliquefaciens</i> industrial applications medical applications agricultural applications metabolic engineering |
| url | https://www.mdpi.com/2076-2607/11/9/2215 |
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