Lignin-Based Porous Biomaterials for Medical and Pharmaceutical Applications
Over the past decade, lignin-based porous biomaterials have been found to have strong potential applications in the areas of drug delivery, tissue engineering, wound dressing, pharmaceutical excipients, biosensors, and medical devices. Lignin-based porous biomaterials have the addition of lignin obt...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Biomedicines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9059/10/4/747 |
| _version_ | 1827621711890087936 |
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| author | Nan Nan Wanhe Hu Jingxin Wang |
| author_facet | Nan Nan Wanhe Hu Jingxin Wang |
| author_sort | Nan Nan |
| collection | DOAJ |
| description | Over the past decade, lignin-based porous biomaterials have been found to have strong potential applications in the areas of drug delivery, tissue engineering, wound dressing, pharmaceutical excipients, biosensors, and medical devices. Lignin-based porous biomaterials have the addition of lignin obtained from lignocellulosic biomass. Lignin as an aromatic compound is likely to modify the materials’ mechanical properties, thermal properties, antioxidant, antibacterial property, biodegradability, and biocompatibility. The size, shape, and distribution of pores can determine the materials’ porous structure, porosity, surface areas, permeability, porosity, water solubility, and adsorption ability. These features could be suitable for medical applications, especially controlled drug delivery systems, wound dressing, and tissue engineering. In this review, we provide an overview of the current status and future potential of lignin-based porous materials for medical and pharmaceutical uses, focusing on material types, key properties, approaches and techniques of modification and fabrication, and promising medical applications. |
| first_indexed | 2024-03-09T11:08:14Z |
| format | Article |
| id | doaj.art-865928d50ee04897b8257dd9962830b4 |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-09T11:08:14Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-865928d50ee04897b8257dd9962830b42023-12-01T00:52:44ZengMDPI AGBiomedicines2227-90592022-03-0110474710.3390/biomedicines10040747Lignin-Based Porous Biomaterials for Medical and Pharmaceutical ApplicationsNan Nan0Wanhe Hu1Jingxin Wang2Center for Sustainable Biomaterials & Bioenergy, West Virginia University, Morgantown, WV 26506, USACenter for Sustainable Biomaterials & Bioenergy, West Virginia University, Morgantown, WV 26506, USACenter for Sustainable Biomaterials & Bioenergy, West Virginia University, Morgantown, WV 26506, USAOver the past decade, lignin-based porous biomaterials have been found to have strong potential applications in the areas of drug delivery, tissue engineering, wound dressing, pharmaceutical excipients, biosensors, and medical devices. Lignin-based porous biomaterials have the addition of lignin obtained from lignocellulosic biomass. Lignin as an aromatic compound is likely to modify the materials’ mechanical properties, thermal properties, antioxidant, antibacterial property, biodegradability, and biocompatibility. The size, shape, and distribution of pores can determine the materials’ porous structure, porosity, surface areas, permeability, porosity, water solubility, and adsorption ability. These features could be suitable for medical applications, especially controlled drug delivery systems, wound dressing, and tissue engineering. In this review, we provide an overview of the current status and future potential of lignin-based porous materials for medical and pharmaceutical uses, focusing on material types, key properties, approaches and techniques of modification and fabrication, and promising medical applications.https://www.mdpi.com/2227-9059/10/4/747ligninporous biomaterialnanocompositedrug deliverytissue engineeringelectrospinning |
| spellingShingle | Nan Nan Wanhe Hu Jingxin Wang Lignin-Based Porous Biomaterials for Medical and Pharmaceutical Applications Biomedicines lignin porous biomaterial nanocomposite drug delivery tissue engineering electrospinning |
| title | Lignin-Based Porous Biomaterials for Medical and Pharmaceutical Applications |
| title_full | Lignin-Based Porous Biomaterials for Medical and Pharmaceutical Applications |
| title_fullStr | Lignin-Based Porous Biomaterials for Medical and Pharmaceutical Applications |
| title_full_unstemmed | Lignin-Based Porous Biomaterials for Medical and Pharmaceutical Applications |
| title_short | Lignin-Based Porous Biomaterials for Medical and Pharmaceutical Applications |
| title_sort | lignin based porous biomaterials for medical and pharmaceutical applications |
| topic | lignin porous biomaterial nanocomposite drug delivery tissue engineering electrospinning |
| url | https://www.mdpi.com/2227-9059/10/4/747 |
| work_keys_str_mv | AT nannan ligninbasedporousbiomaterialsformedicalandpharmaceuticalapplications AT wanhehu ligninbasedporousbiomaterialsformedicalandpharmaceuticalapplications AT jingxinwang ligninbasedporousbiomaterialsformedicalandpharmaceuticalapplications |