Naturally-Occurring Tyrosinase Inhibitors Classified by Enzyme Kinetics and Copper Chelation

Naturally-Occurring Tyrosinase Inhibitors Classified by Enzyme Kinetics and Copper Chelation

Currently, there are three major assaying methods used to validate in vitro whitening activity from natural products: methods using mushroom tyrosinase, human tyrosinase, and dopachrome tautomerase (or tyrosinase-related protein-2, TRP-2). Whitening agent development consists of two ways, melanin sy...

Full description

Bibliographic Details
Main Authors:	Hee-Do Kim, Hyunju Choi, Fukushi Abekura, Jun-Young Park, Woong-Suk Yang, Seung-Hoon Yang, Cheorl-Ho Kim
Format:	Article
Language:	English
Published:	MDPI AG 2023-05-01
Series:	International Journal of Molecular Sciences
Subjects:	tyrosinase inhibitors catalysis site structure kinetics copper chelation
Online Access:	https://www.mdpi.com/1422-0067/24/9/8226

Similar Items

Chelation of Theranostic Copper Radioisotopes with S-Rich Macrocycles: From Radiolabelling of Copper-64 to In Vivo Investigation
by: Marianna Tosato, et al.
Published: (2022-06-01)

EFFECT OF CHELATED AND MINERAL FORMS OF MICRONUTRIENTS ON THEIR CONTENT IN LEAVES AND THE YIELD OF LETTUCE. PART II. COPPER
by: Elzbieta Kozik, et al.
Published: (2008-09-01)

Benefits and drawbacks of current copper chelators in Wilson disease
by: Ioan-Cristian Lupescu, et al.
Published: (2023-03-01)

Influence of chelating agents on structural, optical, and electromgnetic interference properties of copper selenide nanoparticles synthesized via microwave-assisted method
by: Garba, Shitu Ibrahim
Published: (2021)

Effect of Synthetic and Organic Chelators Application on Copper Phytoextraction by Calendula Officinalis L.
by: Vahid Reza Saffari, et al.
Published: (2021-04-01)

Synthesis and Spectral Studies on Heteroleptic Chelated Copper (II) Complexes of Diamine and Acetylacetonate
by: Hamid Golchoubian, et al.
Published: (2012-01-01)

Development of lactobionic acid conjugated-copper chelators as anticancer candidates for hepatocellular carcinoma
by: Xueke Zhao, et al.
Published: (2021-07-01)

Zinc and copper in transfusion-dependent thalassemia patients on different iron chelators in Basrah: A case-control study
by: Balqees Kadhim Hasan, et al.
Published: (2023-01-01)

Iron and Copper Intracellular Chelation as an Anticancer Drug Strategy
by: Kavita Gaur, et al.
Published: (2018-11-01)

Coumarin-Based Compounds as Inhibitors of Tyrosinase/Tyrosine Hydroxylase: Synthesis, Kinetic Studies, and In Silico Approaches
by: Jéssica Alves Nunes, et al.
Published: (2023-03-01)

Extraction of Melanin in Apricot Kernel Shell and the Optimization of Chelating Process of Its Metal Chelates
by: Li GAO, et al.
Published: (2022-07-01)

Tyrosinase Inhibitors: A Perspective
by: Mason A. Baber, et al.
Published: (2023-07-01)

Copper chelating protein hydrolysate from Salvia hispanica L. by pepsin-pancreatin treatment
by: Latha B V, et al.
Published: (2021-01-01)

Exploring Mannosylpurines as Copper Chelators and Cholinesterase Inhibitors with Potential for Alzheimer’s Disease
by: Ignazio Schino, et al.
Published: (2022-12-01)

Heterocyclic Compounds as Synthetic Tyrosinase Inhibitors: Recent Advances
by: Serena Vittorio, et al.
Published: (2023-05-01)

Chelators for Treatment of Iron and Copper Overload: Shift from Low-Molecular-Weight Compounds to Polymers
by: Martin Hruby, et al.
Published: (2021-11-01)

Selective recovery of copper from copper tailings and wastewater using chelating resins with bis-picolylamine functional groups
by: Kosisochi Ibebunjo, et al.
Published: (2024-03-01)

Can copper amino acid chelates reduce the physiological strain of growing rabbits under summer conditions?
by: Fesal Goodb, et al.
Published: (2022-12-01)

Commentary: The Case for Abandoning Therapeutic Chelation of Copper Ions in Alzheimer’s Disease
by: Rosanna Squitti, et al.
Published: (2017-09-01)

The Specific Copper(II) Chelator TDMQ20 Is Efficient for the Treatment of Wilson’s Disease in Mice
by: Yingshan Zhu, et al.
Published: (2023-12-01)

Effects of a Chelated Copper as Growth Promoter on Performance and Carcass Traits in Pigs
by: J. Zhao, et al.
Published: (2014-07-01)

Effect of Copper Chelate Foliar Application on Yield and Yield Components of Four Barley (Hordeum vulgare) Cultivar
by: A. Godrati Azadi, et al.
Published: (2014-02-01)

Tyrosinase Nanoparticles: Understanding the Melanogenesis Pathway by Isolating the Products of Tyrosinase Enzymatic Reaction
by: Paul K. Varghese, et al.
Published: (2021-01-01)

Antioxidant, Iron Chelating and Tyrosinase Inhibitory Activities of Extracts from Talinum triangulare Leach Stem
by: Ana Paula Oliveira Amorim, et al.
Published: (2013-07-01)

Theoretical Studies of Cyanophycin Dipeptides as Inhibitors of Tyrosinases
by: Agnieszka Krzemińska, et al.
Published: (2022-03-01)

Multifunctional Tyrosinase Inhibitor Peptides with Copper Chelating, UV-Absorption and Antioxidant Activities: Kinetic and Docking Studies
by: Pei-Gee Yap, et al.
Published: (2021-03-01)

Phenylthiourea Binding to Human Tyrosinase-Related Protein 1
by: Xuelei Lai, et al.
Published: (2020-01-01)

DOCKING OF TYROSINASE CICLOARTANE INHIBITORS
by: Pablo A. GUTIÉRREZ, et al.
Published: (2009-07-01)

Extraction of heavy metals from copper tailings by ryegrass (Lolium perenne L.) with the assistance of degradable chelating agents
by: Weiwei Wang, et al.
Published: (2024-04-01)

Removal of Chelated Copper by TiO2 Photocatalysis: Synergetic Mechanism Between Cu (II) and Organic Ligands
by: Longli Lin, et al.
Published: (2013-03-01)

Copper catalysis in organic synthesis
by: Sherry R. Chemler
Published: (2015-11-01)

Chelator impact: investigating the pharmacokinetic behavior of copper-64 labeled PD-L1 radioligands
by: Fabian Krutzek, et al.
Published: (2024-02-01)

The Luteolinidin and Petunidin 3-<i>O</i>-Glucoside: A Competitive Inhibitor of Tyrosinase
by: Seo Young Yang, et al.
Published: (2022-09-01)

[15]aneN4S: Synthesis, Thermodynamic Studies and Potential Applications in Chelation Therapy
by: Nuno Torres, et al.
Published: (2014-01-01)

Elucidating the Role of Santalol as a Potent Inhibitor of Tyrosinase: In Vitro and In Silico Approaches
by: Nabeel Ali, et al.
Published: (2022-12-01)

Distribution in Rat Blood and Brain of TDMQ20, a Copper Chelator Designed as a Drug-Candidate for Alzheimer’s Disease
by: Lan Huang, et al.
Published: (2022-12-01)

Copper chelation suppresses epithelial-mesenchymal transition by inhibition of canonical and non-canonical TGF-β signaling pathways in cancer
by: Ensieh M. Poursani, et al.
Published: (2023-07-01)

Preparation and activity study of Ruoqiang jujube polysaccharide copper chelate
by: Aierpati Moheteer, et al.
Published: (2024-01-01)

Genistein Binding to Copper(II)—Solvent Dependence and Effects on Radical Scavenging
by: Jing Yang, et al.
Published: (2017-10-01)

Kushenol A and 8-prenylkaempferol, tyrosinase inhibitors, derived from Sophora flavescens
by: Jang Hoon Kim, et al.
Published: (2018-01-01)