Modification and Functionalization of Zeolites for Curcumin Uptake
This work shows that hierarchical zeolites are promising systems for the delivery of biologically relevant hydrophobic substances, such as curcumin. The validity of using piperine as a promoter of curcumin adsorption was also evaluated. The use of pure curcumin is not medically applicable due to its...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Materials |
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| Online Access: | https://www.mdpi.com/1996-1944/15/18/6316 |
| _version_ | 1797485429981708288 |
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| author | Ewelina Musielak Agnieszka Feliczak-Guzik Mietek Jaroniec Izabela Nowak |
| author_facet | Ewelina Musielak Agnieszka Feliczak-Guzik Mietek Jaroniec Izabela Nowak |
| author_sort | Ewelina Musielak |
| collection | DOAJ |
| description | This work shows that hierarchical zeolites are promising systems for the delivery of biologically relevant hydrophobic substances, such as curcumin. The validity of using piperine as a promoter of curcumin adsorption was also evaluated. The use of pure curcumin is not medically applicable due to its low bioavailability and poor water solubility. To improve the undesirable properties of curcumin, special carriers are used to overcome these shortcomings. Hierarchical zeolites possessing secondary mesoporosity are used as pharmaceutical carrier systems for encapsulating active substances with low water solubility. This porosity facilitates access of larger reagent molecules to the active sites of the material, preserving desirable adsorption properties, acidity, and crystallinity of zeolites. In this work, methods are proposed to synthesize hierarchical zeolites based on a commercial FAU-type zeolite. Studies on the application and adsorption kinetics of curcumin using commercial FAU-type zeolite and hierarchical zeolites based on commercial FAU-type zeolite are also included. |
| first_indexed | 2024-03-09T23:18:40Z |
| format | Article |
| id | doaj.art-866bd234c9cd4168b9773d62bead8aa6 |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-09T23:18:40Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-866bd234c9cd4168b9773d62bead8aa62023-11-23T17:31:31ZengMDPI AGMaterials1996-19442022-09-011518631610.3390/ma15186316Modification and Functionalization of Zeolites for Curcumin UptakeEwelina Musielak0Agnieszka Feliczak-Guzik1Mietek Jaroniec2Izabela Nowak3Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznańskiego 8, 61-614 Poznań, PolandFaculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznańskiego 8, 61-614 Poznań, PolandDepartment of Chemistry and Biochemistry, Kent State University, Kent, OH 44242, USAFaculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznańskiego 8, 61-614 Poznań, PolandThis work shows that hierarchical zeolites are promising systems for the delivery of biologically relevant hydrophobic substances, such as curcumin. The validity of using piperine as a promoter of curcumin adsorption was also evaluated. The use of pure curcumin is not medically applicable due to its low bioavailability and poor water solubility. To improve the undesirable properties of curcumin, special carriers are used to overcome these shortcomings. Hierarchical zeolites possessing secondary mesoporosity are used as pharmaceutical carrier systems for encapsulating active substances with low water solubility. This porosity facilitates access of larger reagent molecules to the active sites of the material, preserving desirable adsorption properties, acidity, and crystallinity of zeolites. In this work, methods are proposed to synthesize hierarchical zeolites based on a commercial FAU-type zeolite. Studies on the application and adsorption kinetics of curcumin using commercial FAU-type zeolite and hierarchical zeolites based on commercial FAU-type zeolite are also included.https://www.mdpi.com/1996-1944/15/18/6316hierarchical zeolitesFAU-type zeolitebiologically active substancescurcuminpiperine |
| spellingShingle | Ewelina Musielak Agnieszka Feliczak-Guzik Mietek Jaroniec Izabela Nowak Modification and Functionalization of Zeolites for Curcumin Uptake Materials hierarchical zeolites FAU-type zeolite biologically active substances curcumin piperine |
| title | Modification and Functionalization of Zeolites for Curcumin Uptake |
| title_full | Modification and Functionalization of Zeolites for Curcumin Uptake |
| title_fullStr | Modification and Functionalization of Zeolites for Curcumin Uptake |
| title_full_unstemmed | Modification and Functionalization of Zeolites for Curcumin Uptake |
| title_short | Modification and Functionalization of Zeolites for Curcumin Uptake |
| title_sort | modification and functionalization of zeolites for curcumin uptake |
| topic | hierarchical zeolites FAU-type zeolite biologically active substances curcumin piperine |
| url | https://www.mdpi.com/1996-1944/15/18/6316 |
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