General aspects about Allium sativum - a review
Abstract Introduction: Garlic has been used as a food and medicinal plant through the years. Antimicrobial, antiviral, and immunostimulatory effects are attributed to garlic, so it is widely recommended to treat diseases like asthma, bronchitis, influenza, and some others. Method: This work'...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Facultad de Farmacia, Universidad de Granada
2021-11-01
|
| Series: | Ars Pharmaceutica |
| Subjects: | |
| Online Access: | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2340-98942021000400471&tlng=en |
| _version_ | 1819175234513666048 |
|---|---|
| author | Arlene Loría Gutiérrez Jeimmy Blanco Barrantes Marta Porras Navarro María Celeste Ortega Monge María José Cerdas Vargas German L Madrigal Redondo |
| author_facet | Arlene Loría Gutiérrez Jeimmy Blanco Barrantes Marta Porras Navarro María Celeste Ortega Monge María José Cerdas Vargas German L Madrigal Redondo |
| author_sort | Arlene Loría Gutiérrez |
| collection | DOAJ |
| description | Abstract Introduction: Garlic has been used as a food and medicinal plant through the years. Antimicrobial, antiviral, and immunostimulatory effects are attributed to garlic, so it is widely recommended to treat diseases like asthma, bronchitis, influenza, and some others. Method: This work's objective was to conduct a literature review and analysis related to garlic medicinal-use, and it's potential as a therapeutic agent and immunostimulant in different diseases and health conditions. The literature review was carried out in the databases Scielo, Clinical Key, Medline and ClinicalTrials.gov, among others. Results: The information consulted supports the health benefits associated with garlic consumption. The crushing of garlic bulbs allows obtaining alliin, which turns into allicin due to enzymatic oxidation. This compound has a fundamental role in the garlic's medicinal properties, and the garlic plant's activity depends on its ability to produce allicin. Preclinical studies have shown the improvement of the immune system, and specific proteins associated with its immunostimulating effect have been identified. In clinical studies, supplements with garlic derivatives have been administered to patients, and a decrease in the incidence of influenza and acute respiratory diseases has been observed. Conclusions: Garlic has been shown to have a significant clinical potential to treat many diseases, and immunomodulatory effects and viral acute respiratory disease prevention have been observed. |
| first_indexed | 2024-12-22T20:51:38Z |
| format | Article |
| id | doaj.art-867057ea7c22427a8cc11c9f78de80ad |
| institution | Directory Open Access Journal |
| issn | 2340-9894 |
| language | English |
| last_indexed | 2024-12-22T20:51:38Z |
| publishDate | 2021-11-01 |
| publisher | Facultad de Farmacia, Universidad de Granada |
| record_format | Article |
| series | Ars Pharmaceutica |
| spelling | doaj.art-867057ea7c22427a8cc11c9f78de80ad2022-12-21T18:13:05ZengFacultad de Farmacia, Universidad de GranadaArs Pharmaceutica2340-98942021-11-0162447148110.30827/ars.v62i4.20843General aspects about Allium sativum - a reviewArlene Loría Gutiérrezhttps://orcid.org/0000-0002-5059-8026Jeimmy Blanco Barranteshttps://orcid.org/0000-0001-5471-8948Marta Porras NavarroMaría Celeste Ortega Mongehttps://orcid.org/0000-0002-8384-9987María José Cerdas Vargashttps://orcid.org/0000-0001-7296-7980German L Madrigal Redondohttps://orcid.org/0000-0002-9856-4044Abstract Introduction: Garlic has been used as a food and medicinal plant through the years. Antimicrobial, antiviral, and immunostimulatory effects are attributed to garlic, so it is widely recommended to treat diseases like asthma, bronchitis, influenza, and some others. Method: This work's objective was to conduct a literature review and analysis related to garlic medicinal-use, and it's potential as a therapeutic agent and immunostimulant in different diseases and health conditions. The literature review was carried out in the databases Scielo, Clinical Key, Medline and ClinicalTrials.gov, among others. Results: The information consulted supports the health benefits associated with garlic consumption. The crushing of garlic bulbs allows obtaining alliin, which turns into allicin due to enzymatic oxidation. This compound has a fundamental role in the garlic's medicinal properties, and the garlic plant's activity depends on its ability to produce allicin. Preclinical studies have shown the improvement of the immune system, and specific proteins associated with its immunostimulating effect have been identified. In clinical studies, supplements with garlic derivatives have been administered to patients, and a decrease in the incidence of influenza and acute respiratory diseases has been observed. Conclusions: Garlic has been shown to have a significant clinical potential to treat many diseases, and immunomodulatory effects and viral acute respiratory disease prevention have been observed.http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2340-98942021000400471&tlng=enGarlicImmunostimulantTherapeuticsAllium sativum L |
| spellingShingle | Arlene Loría Gutiérrez Jeimmy Blanco Barrantes Marta Porras Navarro María Celeste Ortega Monge María José Cerdas Vargas German L Madrigal Redondo General aspects about Allium sativum - a review Ars Pharmaceutica Garlic Immunostimulant Therapeutics Allium sativum L |
| title | General aspects about Allium sativum - a review |
| title_full | General aspects about Allium sativum - a review |
| title_fullStr | General aspects about Allium sativum - a review |
| title_full_unstemmed | General aspects about Allium sativum - a review |
| title_short | General aspects about Allium sativum - a review |
| title_sort | general aspects about allium sativum a review |
| topic | Garlic Immunostimulant Therapeutics Allium sativum L |
| url | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2340-98942021000400471&tlng=en |
| work_keys_str_mv | AT arleneloriagutierrez generalaspectsaboutalliumsativumareview AT jeimmyblancobarrantes generalaspectsaboutalliumsativumareview AT martaporrasnavarro generalaspectsaboutalliumsativumareview AT mariacelesteortegamonge generalaspectsaboutalliumsativumareview AT mariajosecerdasvargas generalaspectsaboutalliumsativumareview AT germanlmadrigalredondo generalaspectsaboutalliumsativumareview |