Research progress on the roles of aldose reductase in diabetic retinopathy

Research progress on the roles of aldose reductase in diabetic retinopathy

Aldose reductase(AR)belonging to nicotinamide-adenine dinucleotide phosphate(NADPH)-dependent aldehyde-keto reductase superfamily, is the key rate-limiting enzyme in the polyol pathway which plays an important role in the body's high-sugar metabolism. AR is widely present in the kidneys, blood...

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Bibliographic Details
Main Authors: Hong-Zhe Li, Cai-Rui Li, Shu-Guang Sun
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2015-07-01
Series:Guoji Yanke Zazhi
Subjects:
aldose reductase
aldose reductase inhibitors
diabetic retinopathy
polyol pathway
polymorphism
Online Access:http://ies.ijo.cn/cn_publish/2015/7/201507015.pdf

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