Template Directed Reversible Photochemical Ligation of Oligodeoxynucleotides

Template Directed Reversible Photochemical Ligation of Oligodeoxynucleotides

We demonstrated that 5-vinyldeoxyuridine (VU) and 5-carboxyvinyldeoxyuridine (CVU) can be used to photoligate a longer oligonucleotide (ODN) from smaller ODNs on a template. By performing irradiation at 366 nm, these artificial nucleotides make photoligated ODNs with high efficiency without any side...

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Bibliographic Details
Main Authors: Kenzo Fujimoto, Shigeo Matuda, Isao Saito, Shigetaka Nakamura, Shinzi Ogasawara
Format: Article
Language:English
Published: MDPI AG 2011-12-01
Series:Molecules
Subjects:
photochemical ligation
5-carboxyvinyldeoxyuridine
5-vinyldeoxyuridine
DNA nanotechnology
Online Access:http://www.mdpi.com/1420-3049/17/1/163/

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