Clinical applications of concentrated growth factors membrane for sealing the socket in alveolar ridge preservation: a randomized controlled trial
Abstract The purpose of this study was to evaluate the efficacy of concentrated growth factor (CGF) membrane for the sealing of alveolar socket in alveolar ridge preservation (ARP). A total of 22 patients with 24 alveolar sockets were recruited and divided randomly into CGF group and Bio-Gide collag...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-11-01
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| Series: | International Journal of Implant Dentistry |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40729-022-00448-w |
| _version_ | 1828191293080076288 |
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| author | Yumeng Liu Xiaoming Li Changwei Jiang Huiying Guo Guisheng Luo Yangyang Huang Changyong Yuan |
| author_facet | Yumeng Liu Xiaoming Li Changwei Jiang Huiying Guo Guisheng Luo Yangyang Huang Changyong Yuan |
| author_sort | Yumeng Liu |
| collection | DOAJ |
| description | Abstract The purpose of this study was to evaluate the efficacy of concentrated growth factor (CGF) membrane for the sealing of alveolar socket in alveolar ridge preservation (ARP). A total of 22 patients with 24 alveolar sockets were recruited and divided randomly into CGF group and Bio-Gide collagen membrane group. The soft tissue wound healing rate was calculated using intraoral scanner at 3, 7, and 14 days after ARP, and the bone resorption volume at 1, 3, and 5 mm below the alveolar ridge was measured by CBCT at 6 months postoperation. The keratinized gingival width was also measured before and 6 months after ridge preservation. In terms of soft tissue healing rate, the CGF group exhibited significant higher than that of Bio-Gide group at both 7 and 14 days after surgery (P < 0.05). However, there was no significantly different in bone resorption rate and the width of keratinized gingival after 6 months (P > 0.05). Therefore, the use of CGFs membranes for wound closure in ARP is a reliable method, but more clinical data are needed to prove it. |
| first_indexed | 2024-04-12T08:36:23Z |
| format | Article |
| id | doaj.art-867dc54ca67148c1af564e72129d8f42 |
| institution | Directory Open Access Journal |
| issn | 2198-4034 |
| language | English |
| last_indexed | 2024-04-12T08:36:23Z |
| publishDate | 2022-11-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | International Journal of Implant Dentistry |
| spelling | doaj.art-867dc54ca67148c1af564e72129d8f422022-12-22T03:40:01ZengSpringerOpenInternational Journal of Implant Dentistry2198-40342022-11-01811910.1186/s40729-022-00448-wClinical applications of concentrated growth factors membrane for sealing the socket in alveolar ridge preservation: a randomized controlled trialYumeng Liu0Xiaoming Li1Changwei Jiang2Huiying Guo3Guisheng Luo4Yangyang Huang5Changyong Yuan6School of Stomatology, Xuzhou Medical UniversityDepartment of Oral Implantology, The Affiliated Stomatological Hospital of Xuzhou Medical UniversityDepartment of Oral Implantology, The Affiliated Stomatological Hospital of Xuzhou Medical UniversitySchool of Stomatology, Xuzhou Medical UniversitySchool of Stomatology, Xuzhou Medical UniversitySchool of Stomatology, Xuzhou Medical UniversityDepartment of Oral Implantology, The Affiliated Stomatological Hospital of Xuzhou Medical UniversityAbstract The purpose of this study was to evaluate the efficacy of concentrated growth factor (CGF) membrane for the sealing of alveolar socket in alveolar ridge preservation (ARP). A total of 22 patients with 24 alveolar sockets were recruited and divided randomly into CGF group and Bio-Gide collagen membrane group. The soft tissue wound healing rate was calculated using intraoral scanner at 3, 7, and 14 days after ARP, and the bone resorption volume at 1, 3, and 5 mm below the alveolar ridge was measured by CBCT at 6 months postoperation. The keratinized gingival width was also measured before and 6 months after ridge preservation. In terms of soft tissue healing rate, the CGF group exhibited significant higher than that of Bio-Gide group at both 7 and 14 days after surgery (P < 0.05). However, there was no significantly different in bone resorption rate and the width of keratinized gingival after 6 months (P > 0.05). Therefore, the use of CGFs membranes for wound closure in ARP is a reliable method, but more clinical data are needed to prove it.https://doi.org/10.1186/s40729-022-00448-wDental implantConcentration growth factorsAlveolar ridge preservationSoft tissue healing |
| spellingShingle | Yumeng Liu Xiaoming Li Changwei Jiang Huiying Guo Guisheng Luo Yangyang Huang Changyong Yuan Clinical applications of concentrated growth factors membrane for sealing the socket in alveolar ridge preservation: a randomized controlled trial International Journal of Implant Dentistry Dental implant Concentration growth factors Alveolar ridge preservation Soft tissue healing |
| title | Clinical applications of concentrated growth factors membrane for sealing the socket in alveolar ridge preservation: a randomized controlled trial |
| title_full | Clinical applications of concentrated growth factors membrane for sealing the socket in alveolar ridge preservation: a randomized controlled trial |
| title_fullStr | Clinical applications of concentrated growth factors membrane for sealing the socket in alveolar ridge preservation: a randomized controlled trial |
| title_full_unstemmed | Clinical applications of concentrated growth factors membrane for sealing the socket in alveolar ridge preservation: a randomized controlled trial |
| title_short | Clinical applications of concentrated growth factors membrane for sealing the socket in alveolar ridge preservation: a randomized controlled trial |
| title_sort | clinical applications of concentrated growth factors membrane for sealing the socket in alveolar ridge preservation a randomized controlled trial |
| topic | Dental implant Concentration growth factors Alveolar ridge preservation Soft tissue healing |
| url | https://doi.org/10.1186/s40729-022-00448-w |
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