Time-To-Treatment of Acute Coronary Syndrome and Unit of First Contact in the ERICO Study

Abstract Background: To the best of our knowledge, there are no studies evaluating the influence of the unit of the first contact on the frequency and time of pharmacological treatment during an acute coronary syndrome (ACS) event. Objectives: The main objective was to investigate if the unit of f...

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Main Authors: Rafael Caire de Oliveira dos Santos, Alessandra Carvalho Goulart, Alan Loureiro Xavier Kisukuri, Rodrigo Martins Brandão, Debora Sitnik, Henrique Lane Staniak, Marcio Sommer Bittencourt, Paulo Andrade Lotufo, Isabela Martins Bensenor, Itamar de Souza Santos
Format: Article
Language:English
Published: Sociedade Brasileira de Cardiologia (SBC)
Series:Arquivos Brasileiros de Cardiologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016004300323&lng=en&tlng=en
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author Rafael Caire de Oliveira dos Santos
Alessandra Carvalho Goulart
Alan Loureiro Xavier Kisukuri
Rodrigo Martins Brandão
Debora Sitnik
Henrique Lane Staniak
Marcio Sommer Bittencourt
Paulo Andrade Lotufo
Isabela Martins Bensenor
Itamar de Souza Santos
author_facet Rafael Caire de Oliveira dos Santos
Alessandra Carvalho Goulart
Alan Loureiro Xavier Kisukuri
Rodrigo Martins Brandão
Debora Sitnik
Henrique Lane Staniak
Marcio Sommer Bittencourt
Paulo Andrade Lotufo
Isabela Martins Bensenor
Itamar de Souza Santos
author_sort Rafael Caire de Oliveira dos Santos
collection DOAJ
description Abstract Background: To the best of our knowledge, there are no studies evaluating the influence of the unit of the first contact on the frequency and time of pharmacological treatment during an acute coronary syndrome (ACS) event. Objectives: The main objective was to investigate if the unit of first contact influenced the frequency and time of aspirin treatment in the Strategy of Registry of Acute Coronary Syndrome (ERICO) study. Methods: We analyzed the pharmacological treatment time in 830 ERICO participants - 700 individuals for whom the hospital was the unit of first contact and 130 who initially sought primary care units. We built logistic regression models to study whether the unit of first contact was associated with a treatment time of less than three hours. Results: Individuals who went to primary care units received the first aspirin dose in those units in 75.6% of the cases. The remaining 24.4% received aspirin at the hospital. Despite this finding, individuals from primary care still had aspirin administered within three hours more frequently than those who went to the hospital (76.8% vs 52.6%; p<0.001 and 100% vs. 70.7%; p=0.001 for non ST-elevation ACS and ST-elevation myocardial infarction, respectively). In adjusted models, individuals coming from primary care were more likely to receive aspirin more quickly (odds ratio: 3.66; 95% confidence interval: 2.06-6.51). Conclusions: In our setting, individuals from primary care were more likely to receive aspirin earlier. Enhancing the ability of primary care units to provide early treatment and safe transportation may be beneficial in similar settings.
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spelling doaj.art-867e046c88964f99a50e668946e5e0b82022-12-22T03:47:43ZengSociedade Brasileira de Cardiologia (SBC)Arquivos Brasileiros de Cardiologia1678-4170107432333010.5935/abc.20160138S0066-782X2016004300323Time-To-Treatment of Acute Coronary Syndrome and Unit of First Contact in the ERICO StudyRafael Caire de Oliveira dos SantosAlessandra Carvalho GoulartAlan Loureiro Xavier KisukuriRodrigo Martins BrandãoDebora SitnikHenrique Lane StaniakMarcio Sommer BittencourtPaulo Andrade LotufoIsabela Martins BensenorItamar de Souza SantosAbstract Background: To the best of our knowledge, there are no studies evaluating the influence of the unit of the first contact on the frequency and time of pharmacological treatment during an acute coronary syndrome (ACS) event. Objectives: The main objective was to investigate if the unit of first contact influenced the frequency and time of aspirin treatment in the Strategy of Registry of Acute Coronary Syndrome (ERICO) study. Methods: We analyzed the pharmacological treatment time in 830 ERICO participants - 700 individuals for whom the hospital was the unit of first contact and 130 who initially sought primary care units. We built logistic regression models to study whether the unit of first contact was associated with a treatment time of less than three hours. Results: Individuals who went to primary care units received the first aspirin dose in those units in 75.6% of the cases. The remaining 24.4% received aspirin at the hospital. Despite this finding, individuals from primary care still had aspirin administered within three hours more frequently than those who went to the hospital (76.8% vs 52.6%; p<0.001 and 100% vs. 70.7%; p=0.001 for non ST-elevation ACS and ST-elevation myocardial infarction, respectively). In adjusted models, individuals coming from primary care were more likely to receive aspirin more quickly (odds ratio: 3.66; 95% confidence interval: 2.06-6.51). Conclusions: In our setting, individuals from primary care were more likely to receive aspirin earlier. Enhancing the ability of primary care units to provide early treatment and safe transportation may be beneficial in similar settings.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016004300323&lng=en&tlng=enAcute Coronary Syndrome / mortalityPrimary Health CareAspirin / administration & dosageAnticoagulants, Time-to-TreatmentCohort Studies
spellingShingle Rafael Caire de Oliveira dos Santos
Alessandra Carvalho Goulart
Alan Loureiro Xavier Kisukuri
Rodrigo Martins Brandão
Debora Sitnik
Henrique Lane Staniak
Marcio Sommer Bittencourt
Paulo Andrade Lotufo
Isabela Martins Bensenor
Itamar de Souza Santos
Time-To-Treatment of Acute Coronary Syndrome and Unit of First Contact in the ERICO Study
Arquivos Brasileiros de Cardiologia
Acute Coronary Syndrome / mortality
Primary Health Care
Aspirin / administration & dosage
Anticoagulants, Time-to-Treatment
Cohort Studies
title Time-To-Treatment of Acute Coronary Syndrome and Unit of First Contact in the ERICO Study
title_full Time-To-Treatment of Acute Coronary Syndrome and Unit of First Contact in the ERICO Study
title_fullStr Time-To-Treatment of Acute Coronary Syndrome and Unit of First Contact in the ERICO Study
title_full_unstemmed Time-To-Treatment of Acute Coronary Syndrome and Unit of First Contact in the ERICO Study
title_short Time-To-Treatment of Acute Coronary Syndrome and Unit of First Contact in the ERICO Study
title_sort time to treatment of acute coronary syndrome and unit of first contact in the erico study
topic Acute Coronary Syndrome / mortality
Primary Health Care
Aspirin / administration & dosage
Anticoagulants, Time-to-Treatment
Cohort Studies
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016004300323&lng=en&tlng=en
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