Corneal endothelial changes evaluation using specular microscope following collagen cross-linking in treatment of keratoconus
Objective The aim of this study was to evaluate the corneal endothelial changes following corneal collagen cross-linking treatment of keratoconus using a specular microscope. Patients and methods The study included 30 eyes of 30 patients with keratoconus, comprsing 16 males and 14 females, with a me...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Delta Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.djo.eg.net/article.asp?issn=1110-9173;year=2020;volume=21;issue=3;spage=153;epage=158;aulast=Elgazzar |
| _version_ | 1818597935334555648 |
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| author | Akram F Elgazzar Reem S Eid Mona M Aly |
| author_facet | Akram F Elgazzar Reem S Eid Mona M Aly |
| author_sort | Akram F Elgazzar |
| collection | DOAJ |
| description | Objective The aim of this study was to evaluate the corneal endothelial changes following corneal collagen cross-linking treatment of keratoconus using a specular microscope.
Patients and methods The study included 30 eyes of 30 patients with keratoconus, comprsing 16 males and 14 females, with a mean age of 28 years. Patients had a standard corneal collagen cross-linking after removal of the corneal epithelium. They were evaluated before and 1 month after the procedure using the specular microscope.
Results The mean preoperative central corneal thickness of the patients was 477.5±35.57 µm, and at 1 month postoperatively, it was 477.9±36.88 µm, with no statistically significant change (P=0.7821). The mean preoperative value of cell density was 2963.1±364.1 cells/mm2 and became 2956.96±363 cells/mm2 1 month postoperatively, with no statistically significant change (P=0.7091). The mean preoperative coefficient of variation value was 36.3±5.9%, whereas 1 month postoperatively, it became 36.2±5.6%, with no statistically significant change (P=0.6951). The mean preoperative value of hexagonal cells was 49.93±7.9% and became 48.5±7.3% 1 month postoperatively, with no statistically significant change (P=0.2078).
Conclusion There were no significant changes in human corneal endothelial parameters, as evaluated with the specular microscope, following cross-linking in keratoconic eyes. |
| first_indexed | 2024-12-16T11:55:42Z |
| format | Article |
| id | doaj.art-868037b77fa543e3a8ede6b711d0ff5b |
| institution | Directory Open Access Journal |
| issn | 1110-9173 2090-4835 |
| language | English |
| last_indexed | 2024-12-16T11:55:42Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Delta Journal of Ophthalmology |
| spelling | doaj.art-868037b77fa543e3a8ede6b711d0ff5b2022-12-21T22:32:33ZengWolters Kluwer Medknow PublicationsDelta Journal of Ophthalmology1110-91732090-48352020-01-0121315315810.4103/DJO.DJO_27_20Corneal endothelial changes evaluation using specular microscope following collagen cross-linking in treatment of keratoconusAkram F ElgazzarReem S EidMona M AlyObjective The aim of this study was to evaluate the corneal endothelial changes following corneal collagen cross-linking treatment of keratoconus using a specular microscope. Patients and methods The study included 30 eyes of 30 patients with keratoconus, comprsing 16 males and 14 females, with a mean age of 28 years. Patients had a standard corneal collagen cross-linking after removal of the corneal epithelium. They were evaluated before and 1 month after the procedure using the specular microscope. Results The mean preoperative central corneal thickness of the patients was 477.5±35.57 µm, and at 1 month postoperatively, it was 477.9±36.88 µm, with no statistically significant change (P=0.7821). The mean preoperative value of cell density was 2963.1±364.1 cells/mm2 and became 2956.96±363 cells/mm2 1 month postoperatively, with no statistically significant change (P=0.7091). The mean preoperative coefficient of variation value was 36.3±5.9%, whereas 1 month postoperatively, it became 36.2±5.6%, with no statistically significant change (P=0.6951). The mean preoperative value of hexagonal cells was 49.93±7.9% and became 48.5±7.3% 1 month postoperatively, with no statistically significant change (P=0.2078). Conclusion There were no significant changes in human corneal endothelial parameters, as evaluated with the specular microscope, following cross-linking in keratoconic eyes.http://www.djo.eg.net/article.asp?issn=1110-9173;year=2020;volume=21;issue=3;spage=153;epage=158;aulast=Elgazzarcorneal endotheliumcross-linkingkeratoconusspecular microscope |
| spellingShingle | Akram F Elgazzar Reem S Eid Mona M Aly Corneal endothelial changes evaluation using specular microscope following collagen cross-linking in treatment of keratoconus Delta Journal of Ophthalmology corneal endothelium cross-linking keratoconus specular microscope |
| title | Corneal endothelial changes evaluation using specular microscope following collagen cross-linking in treatment of keratoconus |
| title_full | Corneal endothelial changes evaluation using specular microscope following collagen cross-linking in treatment of keratoconus |
| title_fullStr | Corneal endothelial changes evaluation using specular microscope following collagen cross-linking in treatment of keratoconus |
| title_full_unstemmed | Corneal endothelial changes evaluation using specular microscope following collagen cross-linking in treatment of keratoconus |
| title_short | Corneal endothelial changes evaluation using specular microscope following collagen cross-linking in treatment of keratoconus |
| title_sort | corneal endothelial changes evaluation using specular microscope following collagen cross linking in treatment of keratoconus |
| topic | corneal endothelium cross-linking keratoconus specular microscope |
| url | http://www.djo.eg.net/article.asp?issn=1110-9173;year=2020;volume=21;issue=3;spage=153;epage=158;aulast=Elgazzar |
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