DNA-PKcs is required for cGAS/STING-dependent viral DNA sensing in human cells
Summary: To mount an efficient interferon response to virus infection, intracellular pattern recognition receptors (PRRs) sense viral nucleic acids and activate anti-viral gene transcription. The mechanisms by which intracellular DNA and DNA viruses are sensed are relevant not only to anti-viral inn...
Hlavní autoři: | , , , , , , |
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Médium: | Článek |
Jazyk: | English |
Vydáno: |
Elsevier
2024-01-01
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Edice: | iScience |
Témata: | |
On-line přístup: | http://www.sciencedirect.com/science/article/pii/S2589004223028377 |