DNA-PKcs is required for cGAS/STING-dependent viral DNA sensing in human cells

DNA-PKcs is required for cGAS/STING-dependent viral DNA sensing in human cells

Summary: To mount an efficient interferon response to virus infection, intracellular pattern recognition receptors (PRRs) sense viral nucleic acids and activate anti-viral gene transcription. The mechanisms by which intracellular DNA and DNA viruses are sensed are relevant not only to anti-viral inn...

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Bibliographic Details
Main Authors:	Dayana B. Hristova, Marisa Oliveira, Emma Wagner, Alan Melcher, Kevin J. Harrington, Alexandre Belot, Brian J. Ferguson
Format:	Article
Language:	English
Published:	Elsevier 2024-01-01
Series:	iScience
Subjects:	Virology Molecular biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004223028377

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