Idiopathic intracranial hypertension: Clinical profile and outcome
Background: It has been a long standing challenge to clinicians and investigators to explain the pathophysiology of Idiopathic Intracranial Hypertension (IIH).Therefore, the goal of this study is to delineate the clinical course of this disorder. Aim: To delineate the clinical course of Idiopathic I...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Journal of Clinical Ophthalmology and Research |
| Subjects: | |
| Online Access: | http://www.jcor.in/article.asp?issn=2320-3897;year=2016;volume=4;issue=1;spage=25;epage=29;aulast=Pai |
| _version_ | 1828342784040370176 |
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| author | Shobha G Pai Trisha Sharma Richa Gupta |
| author_facet | Shobha G Pai Trisha Sharma Richa Gupta |
| author_sort | Shobha G Pai |
| collection | DOAJ |
| description | Background: It has been a long standing challenge to clinicians and investigators to explain the pathophysiology of Idiopathic Intracranial Hypertension (IIH).Therefore, the goal of this study is to delineate the clinical course of this disorder. Aim: To delineate the clinical course of Idiopathic Intracranial Hypertension with an emphasis on visual prognosis. Settings and Design: Prospective, observational study of 18 patients. Materials and Methods: Patients with unilateral or bilateral disc oedema; CSF pressure >25 cm H 2 O non- focal neurological examination, and normal CT/MRI/MRV scans were included in the study, while those with concurrent ocular disease were excluded .Ocular examination, visual acuity, fundus photography and visual fields evaluation was done at presentation and during follow up visits for a period of two years. Statistical analysis: Descriptive study. Results: Of the 18 patients, 16 were females. The average age of onset was 31.5 years. Hypertension was the most common systemic comorbidity, seen in 5 patients. Headache was the most common presenting symptom, seen in all 18 patients .Diminution of vision was seen in 16 eyes, out of which 14 improved while 2 showed progressive impairment of vision. Abnormal visual field tests included an enlarged blind spot in 11 out of 36 eyes and peripheral constriction in 14 out of 36 eyes .17 patients had a bilateral and symmetric disc swelling. A CSF opening pressure of more than 40 cm of H 2 O was noted in 6 patients. All the patients were managed medically with diuretics therapy (acetazolamide) and weight reduction. Conclusion: A strong suspicion of Idiopathic Intracranial Hypertension in chronic severe headaches and immediate investigations followed by proper treatment can salvage vision of patients even in cases with established papilledema. |
| first_indexed | 2024-04-13T23:34:23Z |
| format | Article |
| id | doaj.art-8682b6bf075e487397998138fbe006cc |
| institution | Directory Open Access Journal |
| issn | 2320-3897 |
| language | English |
| last_indexed | 2024-04-13T23:34:23Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Clinical Ophthalmology and Research |
| spelling | doaj.art-8682b6bf075e487397998138fbe006cc2022-12-22T02:24:47ZengWolters Kluwer Medknow PublicationsJournal of Clinical Ophthalmology and Research2320-38972016-01-0141252910.4103/2320-3897.174402Idiopathic intracranial hypertension: Clinical profile and outcomeShobha G PaiTrisha SharmaRicha GuptaBackground: It has been a long standing challenge to clinicians and investigators to explain the pathophysiology of Idiopathic Intracranial Hypertension (IIH).Therefore, the goal of this study is to delineate the clinical course of this disorder. Aim: To delineate the clinical course of Idiopathic Intracranial Hypertension with an emphasis on visual prognosis. Settings and Design: Prospective, observational study of 18 patients. Materials and Methods: Patients with unilateral or bilateral disc oedema; CSF pressure >25 cm H 2 O non- focal neurological examination, and normal CT/MRI/MRV scans were included in the study, while those with concurrent ocular disease were excluded .Ocular examination, visual acuity, fundus photography and visual fields evaluation was done at presentation and during follow up visits for a period of two years. Statistical analysis: Descriptive study. Results: Of the 18 patients, 16 were females. The average age of onset was 31.5 years. Hypertension was the most common systemic comorbidity, seen in 5 patients. Headache was the most common presenting symptom, seen in all 18 patients .Diminution of vision was seen in 16 eyes, out of which 14 improved while 2 showed progressive impairment of vision. Abnormal visual field tests included an enlarged blind spot in 11 out of 36 eyes and peripheral constriction in 14 out of 36 eyes .17 patients had a bilateral and symmetric disc swelling. A CSF opening pressure of more than 40 cm of H 2 O was noted in 6 patients. All the patients were managed medically with diuretics therapy (acetazolamide) and weight reduction. Conclusion: A strong suspicion of Idiopathic Intracranial Hypertension in chronic severe headaches and immediate investigations followed by proper treatment can salvage vision of patients even in cases with established papilledema.http://www.jcor.in/article.asp?issn=2320-3897;year=2016;volume=4;issue=1;spage=25;epage=29;aulast=PaiIdiopathic Intracranial HypertensionPseudotumor cerebripapilledemaheadache |
| spellingShingle | Shobha G Pai Trisha Sharma Richa Gupta Idiopathic intracranial hypertension: Clinical profile and outcome Journal of Clinical Ophthalmology and Research Idiopathic Intracranial Hypertension Pseudotumor cerebri papilledema headache |
| title | Idiopathic intracranial hypertension: Clinical profile and outcome |
| title_full | Idiopathic intracranial hypertension: Clinical profile and outcome |
| title_fullStr | Idiopathic intracranial hypertension: Clinical profile and outcome |
| title_full_unstemmed | Idiopathic intracranial hypertension: Clinical profile and outcome |
| title_short | Idiopathic intracranial hypertension: Clinical profile and outcome |
| title_sort | idiopathic intracranial hypertension clinical profile and outcome |
| topic | Idiopathic Intracranial Hypertension Pseudotumor cerebri papilledema headache |
| url | http://www.jcor.in/article.asp?issn=2320-3897;year=2016;volume=4;issue=1;spage=25;epage=29;aulast=Pai |
| work_keys_str_mv | AT shobhagpai idiopathicintracranialhypertensionclinicalprofileandoutcome AT trishasharma idiopathicintracranialhypertensionclinicalprofileandoutcome AT richagupta idiopathicintracranialhypertensionclinicalprofileandoutcome |