Comparative Analysis of Inflammatory Cytokine Release and Alveolar Epithelial Barrier Invasion in a Transwell® Bilayer Model of Mucormycosis

Comparative Analysis of Inflammatory Cytokine Release and Alveolar Epithelial Barrier Invasion in a Transwell® Bilayer Model of Mucormycosis

Understanding the mechanisms of early invasion and epithelial defense in opportunistic mold infections is crucial for the evaluation of diagnostic biomarkers and novel treatment strategies. Recent studies revealed unique characteristics of the immunopathology of mucormycoses. We therefore adapted an...

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Bibliographic Details
Main Authors: Stanislav Belic, Lukas Page, Maria Lazariotou, Ana Maria Waaga-Gasser, Mariola Dragan, Jan Springer, Juergen Loeffler, Charles Oliver Morton, Hermann Einsele, Andrew J. Ullmann, Sebastian Wurster
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Microbiology
Subjects:
mucormycosis
alveolar epithelium
in vitro model
cytokines
dendritic cells
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.03204/full

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