Guanfacine as an effective drug for the treatment of tic disorder. Case report
Introduction A 15-year-old man who comes to the consultation referred from neurology for a poorly progressive tic disorder that is resistant to treatment. This is a patient with no relevant medical history. He has good academic performance, without symptoms of inattention, hyperactivity or impulsi...
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2021-04-01
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| Series: | European Psychiatry |
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| Online Access: | https://www.cambridge.org/core/product/identifier/S0924933821016734/type/journal_article |
| _version_ | 1797617424165502976 |
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| author | P. Del Sol Calderon A. Izquierdo M. García Moreno |
| author_facet | P. Del Sol Calderon A. Izquierdo M. García Moreno |
| author_sort | P. Del Sol Calderon |
| collection | DOAJ |
| description |
Introduction
A 15-year-old man who comes to the consultation referred from neurology for a poorly progressive tic disorder that is resistant to treatment. This is a patient with no relevant medical history. He has good academic performance, without symptoms of inattention, hyperactivity or impulsivity. He does not present buccophonatory tics
Objectives
To Show guanfacine as a efficient treatment fot tics disorder
Methods
Case report
Results
He has presented complex motor tics as cervical contractions that have had to receive physiotherapeutic treatment. He also presents simple ocular tics. The patient at our evaluation is on a 4 mg dose of pimozide without response. He was previously on risperidone. It was decided to start treatment with guanfacine up to 5 mg with reduction of pimozide, to 1 mg. The patient with this dose adjustment shows a notable improvement in the frequency and intensity of the tics, both cervical and ocular. The patient also refers to a feeling of being calmer and being able to face stressful situations such as being exposed to social relationships, intervening more in class without increasing their anxiety levels.
Conclusions
Guanfacine is a selective alpha-2a adrenergic receptor agonist that has an indication for attention deficit hyperactivity disorder. Like its precursor, clonidine, there is more and more literature that proposes this medication and others for ADHD as useful drugs in pathologies such as tic disorder. It has a safe use profile, which with progressive adjustment and hardly any side effects is placed as a treatment to take into account in this pathology.
Disclosure
No significant relationships.
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| first_indexed | 2024-03-11T07:55:48Z |
| format | Article |
| id | doaj.art-8684f9d2289049fcb038d757ee03f10f |
| institution | Directory Open Access Journal |
| issn | 0924-9338 1778-3585 |
| language | English |
| last_indexed | 2024-03-11T07:55:48Z |
| publishDate | 2021-04-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj.art-8684f9d2289049fcb038d757ee03f10f2023-11-17T05:05:52ZengCambridge University PressEuropean Psychiatry0924-93381778-35852021-04-0164S629S62910.1192/j.eurpsy.2021.1673Guanfacine as an effective drug for the treatment of tic disorder. Case reportP. Del Sol Calderon0A. Izquierdo1M. García Moreno2Psychiatry, Hospital Universitario Puerta de Hierro, Majadahonda, SpainPsychiatry, Hospital Universitario Puerta de Hierro, Majadahonda, SpainPsychiatry, Hospital Universitario Puerta de Hierro, Majadahonda, Spain Introduction A 15-year-old man who comes to the consultation referred from neurology for a poorly progressive tic disorder that is resistant to treatment. This is a patient with no relevant medical history. He has good academic performance, without symptoms of inattention, hyperactivity or impulsivity. He does not present buccophonatory tics Objectives To Show guanfacine as a efficient treatment fot tics disorder Methods Case report Results He has presented complex motor tics as cervical contractions that have had to receive physiotherapeutic treatment. He also presents simple ocular tics. The patient at our evaluation is on a 4 mg dose of pimozide without response. He was previously on risperidone. It was decided to start treatment with guanfacine up to 5 mg with reduction of pimozide, to 1 mg. The patient with this dose adjustment shows a notable improvement in the frequency and intensity of the tics, both cervical and ocular. The patient also refers to a feeling of being calmer and being able to face stressful situations such as being exposed to social relationships, intervening more in class without increasing their anxiety levels. Conclusions Guanfacine is a selective alpha-2a adrenergic receptor agonist that has an indication for attention deficit hyperactivity disorder. Like its precursor, clonidine, there is more and more literature that proposes this medication and others for ADHD as useful drugs in pathologies such as tic disorder. It has a safe use profile, which with progressive adjustment and hardly any side effects is placed as a treatment to take into account in this pathology. Disclosure No significant relationships. https://www.cambridge.org/core/product/identifier/S0924933821016734/type/journal_articleTicsTreatmentchild and adolescent |
| spellingShingle | P. Del Sol Calderon A. Izquierdo M. García Moreno Guanfacine as an effective drug for the treatment of tic disorder. Case report European Psychiatry Tics Treatment child and adolescent |
| title | Guanfacine as an effective drug for the treatment of tic disorder. Case report |
| title_full | Guanfacine as an effective drug for the treatment of tic disorder. Case report |
| title_fullStr | Guanfacine as an effective drug for the treatment of tic disorder. Case report |
| title_full_unstemmed | Guanfacine as an effective drug for the treatment of tic disorder. Case report |
| title_short | Guanfacine as an effective drug for the treatment of tic disorder. Case report |
| title_sort | guanfacine as an effective drug for the treatment of tic disorder case report |
| topic | Tics Treatment child and adolescent |
| url | https://www.cambridge.org/core/product/identifier/S0924933821016734/type/journal_article |
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