Relation between epicardial adipose tissue thickness and blood pressure levels in prehypertension
Objectives: Increased epicardial adipose tissue (EAT) thickness is a risk factor for cardiovascular diseases. Previous studies have demonstrated that EAT thickness is increased in patients with hypertension compared with normotensive individuals. In the current study, we aimed to evaluate whether e...
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| Format: | Article |
| Language: | English |
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KARE Publishing
2014-06-01
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| Series: | Türk Kardiyoloji Derneği Arşivi |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-35477 |
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| author | Osman Turak Fırat Özcan Uğur Canpolat Mehmet A Mendi Fatih Öksüz Özcan Özeke Derya Tok Kumral Çağlı Dursun Aras Sinan Aydoğdu |
| author_facet | Osman Turak Fırat Özcan Uğur Canpolat Mehmet A Mendi Fatih Öksüz Özcan Özeke Derya Tok Kumral Çağlı Dursun Aras Sinan Aydoğdu |
| author_sort | Osman Turak |
| collection | DOAJ |
| description | Objectives: Increased epicardial adipose tissue (EAT) thickness is a risk factor for cardiovascular diseases. Previous studies have demonstrated that EAT thickness is increased in patients with hypertension compared with normotensive individuals. In the current study, we aimed to evaluate whether echocardiographically measured EAT thickness differs among patients with normotension, prehypertension, hypertension, and the relation between EAT thickness and blood pressure levels in prehypertensives.
Study design: Patients with prehypertension (n=50) and hypertension (n=50) and normotensive healthy subjects (n=50) according to the American Hypertension Guidelines (Joint National Committee 7) were enrolled in the study. All participants underwent transthoracic echocardiographic examination. EAT thickness was measured from the parasternal long-axis view at end-systole.
Results: Compared with normotensives, EAT thickness was significantly increased in subjects with prehypertension and hypertension (4.1+-1.1 mm, 5.4+-1.3 mm and 6.6+-1.5 mm, respectively, p<0.001). After adjustment for confounding factors like age, gender, high-density lipoprotein, waist circumference, and body mass index, EAT thickness in the normotensive, prehypertensive and hypertensive groups was measured as 4.3+-1.2 mm, 5.3+-1.2 mm and 6.4+-1.4 mm, respectively (p=0.001). In the prehypertensive group, multivariable linear regression analysis showed that EAT thickness was positively correlated with both systolic (r=0.305, p=0.001) and diastolic (r=0.297, p=0.001) blood pressures, independent of other risk factors.
Conclusion: In addition to hypertensive subjects, echocardiographically measured EAT thickness is increased in prehypertensive patients when compared with normotensive subjects, independent of other factors. Additionally, increased EAT thickness is significantly correlated with systolic and diastolic blood pressure levels in patients with prehypertension. |
| first_indexed | 2024-04-10T12:00:29Z |
| format | Article |
| id | doaj.art-868a1d689e9d4985a25a5ca086749106 |
| institution | Directory Open Access Journal |
| issn | 1016-5169 |
| language | English |
| last_indexed | 2024-04-10T12:00:29Z |
| publishDate | 2014-06-01 |
| publisher | KARE Publishing |
| record_format | Article |
| series | Türk Kardiyoloji Derneği Arşivi |
| spelling | doaj.art-868a1d689e9d4985a25a5ca0867491062023-02-15T16:16:38ZengKARE PublishingTürk Kardiyoloji Derneği Arşivi1016-51692014-06-0142435836410.5543/tkda.2014.35477TKDA-35477Relation between epicardial adipose tissue thickness and blood pressure levels in prehypertensionOsman Turak0Fırat Özcan1Uğur Canpolat2Mehmet A Mendi3Fatih Öksüz4Özcan Özeke5Derya Tok6Kumral Çağlı7Dursun Aras8Sinan Aydoğdu9Türkiye Yüksek Ihtisas Education And Research Hospital, Department Of Cardiology, Ankara, TurkeyTürkiye Yüksek Ihtisas Education And Research Hospital, Department Of Cardiology, Ankara, TurkeyTürkiye Yüksek Ihtisas Education And Research Hospital, Department Of Cardiology, Ankara, TurkeyTürkiye Yüksek Ihtisas Education And Research Hospital, Department Of Cardiology, Ankara, TurkeyTürkiye Yüksek Ihtisas Education And Research Hospital, Department Of Cardiology, Ankara, TurkeyTürkiye Yüksek Ihtisas Education And Research Hospital, Department Of Cardiology, Ankara, TurkeyTürkiye Yüksek Ihtisas Education And Research Hospital, Department Of Cardiology, Ankara, TurkeyTürkiye Yüksek Ihtisas Education And Research Hospital, Department Of Cardiology, Ankara, TurkeyTürkiye Yüksek Ihtisas Education And Research Hospital, Department Of Cardiology, Ankara, TurkeyTürkiye Yüksek Ihtisas Education And Research Hospital, Department Of Cardiology, Ankara, TurkeyObjectives: Increased epicardial adipose tissue (EAT) thickness is a risk factor for cardiovascular diseases. Previous studies have demonstrated that EAT thickness is increased in patients with hypertension compared with normotensive individuals. In the current study, we aimed to evaluate whether echocardiographically measured EAT thickness differs among patients with normotension, prehypertension, hypertension, and the relation between EAT thickness and blood pressure levels in prehypertensives. Study design: Patients with prehypertension (n=50) and hypertension (n=50) and normotensive healthy subjects (n=50) according to the American Hypertension Guidelines (Joint National Committee 7) were enrolled in the study. All participants underwent transthoracic echocardiographic examination. EAT thickness was measured from the parasternal long-axis view at end-systole. Results: Compared with normotensives, EAT thickness was significantly increased in subjects with prehypertension and hypertension (4.1+-1.1 mm, 5.4+-1.3 mm and 6.6+-1.5 mm, respectively, p<0.001). After adjustment for confounding factors like age, gender, high-density lipoprotein, waist circumference, and body mass index, EAT thickness in the normotensive, prehypertensive and hypertensive groups was measured as 4.3+-1.2 mm, 5.3+-1.2 mm and 6.4+-1.4 mm, respectively (p=0.001). In the prehypertensive group, multivariable linear regression analysis showed that EAT thickness was positively correlated with both systolic (r=0.305, p=0.001) and diastolic (r=0.297, p=0.001) blood pressures, independent of other risk factors. Conclusion: In addition to hypertensive subjects, echocardiographically measured EAT thickness is increased in prehypertensive patients when compared with normotensive subjects, independent of other factors. Additionally, increased EAT thickness is significantly correlated with systolic and diastolic blood pressure levels in patients with prehypertension.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-35477echocardiographyepicardium; hypertension; blood pressure; body weight; adipose tissue/pathology. |
| spellingShingle | Osman Turak Fırat Özcan Uğur Canpolat Mehmet A Mendi Fatih Öksüz Özcan Özeke Derya Tok Kumral Çağlı Dursun Aras Sinan Aydoğdu Relation between epicardial adipose tissue thickness and blood pressure levels in prehypertension Türk Kardiyoloji Derneği Arşivi echocardiography epicardium; hypertension; blood pressure; body weight; adipose tissue/pathology. |
| title | Relation between epicardial adipose tissue thickness and blood pressure levels in prehypertension |
| title_full | Relation between epicardial adipose tissue thickness and blood pressure levels in prehypertension |
| title_fullStr | Relation between epicardial adipose tissue thickness and blood pressure levels in prehypertension |
| title_full_unstemmed | Relation between epicardial adipose tissue thickness and blood pressure levels in prehypertension |
| title_short | Relation between epicardial adipose tissue thickness and blood pressure levels in prehypertension |
| title_sort | relation between epicardial adipose tissue thickness and blood pressure levels in prehypertension |
| topic | echocardiography epicardium; hypertension; blood pressure; body weight; adipose tissue/pathology. |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-35477 |
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