Acute cervicitis resembling gastric-type mucinous adenocarcinoma that was definitively diagnosed by cervical conization: A case report
Although imaging studies are not typically performed for clinical diagnosis of cervicitis, in this case magnetic resonance imaging (MRI) was performed because a lesion with a tumor-like gross appearance was found in the uterine cervix. We present a case of cervicitis in which clinical, imaging and p...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-05-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043323001218 |
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| author | Mai Funakoshi, MD Go Nakai, MD, PhD Takashi Yamada, MD, PhD Masahide Ohmichi, MD, PhD Kazuhiro Yamamoto, MD, PhD Keigo Osuga, MD, PhD |
| author_facet | Mai Funakoshi, MD Go Nakai, MD, PhD Takashi Yamada, MD, PhD Masahide Ohmichi, MD, PhD Kazuhiro Yamamoto, MD, PhD Keigo Osuga, MD, PhD |
| author_sort | Mai Funakoshi, MD |
| collection | DOAJ |
| description | Although imaging studies are not typically performed for clinical diagnosis of cervicitis, in this case magnetic resonance imaging (MRI) was performed because a lesion with a tumor-like gross appearance was found in the uterine cervix. We present a case of cervicitis in which clinical, imaging and pathological features overlapped with those of gastric-type mucinous adenocarcinoma (GAS). The patient, a 30-year-old woman, was referred to a gynecologist with a complaint of watery vaginal discharge. On visual examination, the uterine cervix was irregularly enlarged and bled easily, suggesting cervical cancer. The next day, the patient had a fever of 39°C and blisters appeared on her vulva due to herpes simplex virus type II infection. MRI showed a diffusely enlarged cervix with poorly marginated high signal intensity on T2-weighted imaging (WI) and apparent diffusion coefficient map as well as strong enhancement on contrast-enhanced T1WI, which are findings consistent with GAS. Although a punch biopsy showed only mild atypia of the cervical glands, this was not enough to completely rule out GAS. Consequently, laser conization of the lesion was performed for definitive diagnosis, and the diagnosis of cervicitis was made. Acute cervicitis can be difficult to differentiate from GAS based on symptoms, results of cervical biopsy and MR imaging because of their overlapping features. Even when a patient presents with a lesion with tumor-like gross appearance, acute cervicitis should be included in the differential diagnosis if the result of cervical biopsy is negative, especially when accompanied by infection-like fever. |
| first_indexed | 2024-04-09T20:08:50Z |
| format | Article |
| id | doaj.art-868c3987df414faf9f31d133b868134c |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-04-09T20:08:50Z |
| publishDate | 2023-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-868c3987df414faf9f31d133b868134c2023-04-01T08:46:21ZengElsevierRadiology Case Reports1930-04332023-05-0118517671771Acute cervicitis resembling gastric-type mucinous adenocarcinoma that was definitively diagnosed by cervical conization: A case reportMai Funakoshi, MD0Go Nakai, MD, PhD1Takashi Yamada, MD, PhD2Masahide Ohmichi, MD, PhD3Kazuhiro Yamamoto, MD, PhD4Keigo Osuga, MD, PhD5Department of Diagnostic Radiology, Osaka Medical and Pharmaceutical University, 2-7 Daigaku-machi, Takatsuki City, Osaka 569-8686, JapanDepartment of Diagnostic Radiology, Osaka Medical and Pharmaceutical University, 2-7 Daigaku-machi, Takatsuki City, Osaka 569-8686, Japan; Corresponding author.Department of Pathology, Osaka Medical and Pharmaceutical University, 2-7 Daigaku-machi, Takatsuki City, Osaka 569-8686, JapanDepartment of Obstetrics and Gynecology, Osaka Medical and Pharmaceutical University, 2-7 Daigaku-machi, Takatsuki City, Osaka 569-8686, JapanDepartment of Diagnostic Radiology, Osaka Medical and Pharmaceutical University, 2-7 Daigaku-machi, Takatsuki City, Osaka 569-8686, JapanDepartment of Diagnostic Radiology, Osaka Medical and Pharmaceutical University, 2-7 Daigaku-machi, Takatsuki City, Osaka 569-8686, JapanAlthough imaging studies are not typically performed for clinical diagnosis of cervicitis, in this case magnetic resonance imaging (MRI) was performed because a lesion with a tumor-like gross appearance was found in the uterine cervix. We present a case of cervicitis in which clinical, imaging and pathological features overlapped with those of gastric-type mucinous adenocarcinoma (GAS). The patient, a 30-year-old woman, was referred to a gynecologist with a complaint of watery vaginal discharge. On visual examination, the uterine cervix was irregularly enlarged and bled easily, suggesting cervical cancer. The next day, the patient had a fever of 39°C and blisters appeared on her vulva due to herpes simplex virus type II infection. MRI showed a diffusely enlarged cervix with poorly marginated high signal intensity on T2-weighted imaging (WI) and apparent diffusion coefficient map as well as strong enhancement on contrast-enhanced T1WI, which are findings consistent with GAS. Although a punch biopsy showed only mild atypia of the cervical glands, this was not enough to completely rule out GAS. Consequently, laser conization of the lesion was performed for definitive diagnosis, and the diagnosis of cervicitis was made. Acute cervicitis can be difficult to differentiate from GAS based on symptoms, results of cervical biopsy and MR imaging because of their overlapping features. Even when a patient presents with a lesion with tumor-like gross appearance, acute cervicitis should be included in the differential diagnosis if the result of cervical biopsy is negative, especially when accompanied by infection-like fever.http://www.sciencedirect.com/science/article/pii/S1930043323001218Uterine CervicitisDiagnostic ImagingAdenocarcinomaMucinousMagnetic Resonance ImagingPositron-Emission Tomography |
| spellingShingle | Mai Funakoshi, MD Go Nakai, MD, PhD Takashi Yamada, MD, PhD Masahide Ohmichi, MD, PhD Kazuhiro Yamamoto, MD, PhD Keigo Osuga, MD, PhD Acute cervicitis resembling gastric-type mucinous adenocarcinoma that was definitively diagnosed by cervical conization: A case report Radiology Case Reports Uterine Cervicitis Diagnostic Imaging Adenocarcinoma Mucinous Magnetic Resonance Imaging Positron-Emission Tomography |
| title | Acute cervicitis resembling gastric-type mucinous adenocarcinoma that was definitively diagnosed by cervical conization: A case report |
| title_full | Acute cervicitis resembling gastric-type mucinous adenocarcinoma that was definitively diagnosed by cervical conization: A case report |
| title_fullStr | Acute cervicitis resembling gastric-type mucinous adenocarcinoma that was definitively diagnosed by cervical conization: A case report |
| title_full_unstemmed | Acute cervicitis resembling gastric-type mucinous adenocarcinoma that was definitively diagnosed by cervical conization: A case report |
| title_short | Acute cervicitis resembling gastric-type mucinous adenocarcinoma that was definitively diagnosed by cervical conization: A case report |
| title_sort | acute cervicitis resembling gastric type mucinous adenocarcinoma that was definitively diagnosed by cervical conization a case report |
| topic | Uterine Cervicitis Diagnostic Imaging Adenocarcinoma Mucinous Magnetic Resonance Imaging Positron-Emission Tomography |
| url | http://www.sciencedirect.com/science/article/pii/S1930043323001218 |
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