Corilagin: A Novel Antivirulence Strategy to Alleviate <i>Streptococcus pneumoniae</i> Infection by Diminishing Pneumolysin Oligomers

Corilagin: A Novel Antivirulence Strategy to Alleviate <i>Streptococcus pneumoniae</i> Infection by Diminishing Pneumolysin Oligomers

Pneumolysin (PLY) is a significant virulence factor of <i>Streptococcus pneumoniae</i> (<i>S. pneumoniae</i>), able to break through the defense system of a host and mediate the occurrence of a series of infections. Therefore, PLY as the most ideal target to prevent <i>...

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Bibliographic Details
Main Authors: Qiushuang Sheng, Xiaoning Hou, Nan Wang, Minda Liu, Haoyu Zhu, Xuming Deng, Xiaoying Liang, Gefu Chi
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Molecules
Subjects:
corilagin
pneumolysin
antivirulence
molecular docking
<i>Streptococcus pneumoniae</i>
Online Access:https://www.mdpi.com/1420-3049/27/16/5063

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