Laser in-situ keratomileusis in patients with diabetes mellitus: a review of the literature

Rachel G Simpson,1 Majid Moshirfar,2 Jason N Edmonds,2 Steven M Christiansen21University of Arizona College of Medicine, Phoenix, AZ; 2Moran Eye Center, University of Utah School of Medicine, Salt Lake City, UT, USAPurpose: A growing number of diabetic patients request laser in situ keratomileusis (...

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Main Authors: Simpson RG, Moshirfar M, Edmonds JN, Christiansen SM
Format: Article
Language:English
Published: Dove Medical Press 2012-10-01
Series:Clinical Ophthalmology
Online Access:http://www.dovepress.com/laser-in-situ-keratomileusis-in-patients-with-diabetes-mellitus-a-revi-a11256
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author Simpson RG
Moshirfar M
Edmonds JN
Christiansen SM
author_facet Simpson RG
Moshirfar M
Edmonds JN
Christiansen SM
author_sort Simpson RG
collection DOAJ
description Rachel G Simpson,1 Majid Moshirfar,2 Jason N Edmonds,2 Steven M Christiansen21University of Arizona College of Medicine, Phoenix, AZ; 2Moran Eye Center, University of Utah School of Medicine, Salt Lake City, UT, USAPurpose: A growing number of diabetic patients request laser in situ keratomileusis (LASIK) for elective vision correction each year. While the United States Food and Drug Administration considers diabetes a relative contraindication to LASIK surgery, there are several reports in the literature of LASIK being performed safely in this patient population. The purpose of this review was to examine whether diabetes should still be considered a contraindication to LASIK surgery by reviewing the ocular and systemic complications of diabetes, and examining the existing data on the outcomes of LASIK in diabetic patients.Methods: A literature review was conducted through PubMed, Medline, and Ovid to identify any study on LASIK surgery in patients with diabetes mellitus. This search was conducted without date restrictions. The search used the Medical Subject Headings (MeSH®) term LASIK linked by the word “and” to the following MeSH and natural language terms: diabetes, diabetes mellitus, systemic disease, and contraindications. Abstracts for all studies meeting initial search criteria were reviewed for relevance. There were no prospective clinical studies identified. Three retrospective studies were identified. Key sources from these papers were identified, reviewed, and included as appropriate. An additional literature search was conducted to identify any study of ocular surgery on patients with diabetes using the MeSH terms refractive surgery, photorefractive keratectomy, radial keratotomy, cataract surgery, vitrectomy, and iridectomy linked by the word “and” to the following MeSH terms: diabetes, diabetes mellitus, and systemic disease. This search was conducted without date restrictions. Abstracts of studies meeting the initial search criteria were reviewed and articles deemed relevant to the subject were included in this review.Conclusion: LASIK may be safe in diabetic patients with tight glycemic control and no ocular or systemic complications.Keywords: diabetes mellitus, diabetic keratopathy, diabetic corneal neuropathy, refractive surgery, LASIK surgery
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spelling doaj.art-868f3ac363fb46188ddba87bb3edd7bf2022-12-21T19:16:37ZengDove Medical PressClinical Ophthalmology1177-54671177-54832012-10-012012default16651674Laser in-situ keratomileusis in patients with diabetes mellitus: a review of the literatureSimpson RGMoshirfar MEdmonds JNChristiansen SMRachel G Simpson,1 Majid Moshirfar,2 Jason N Edmonds,2 Steven M Christiansen21University of Arizona College of Medicine, Phoenix, AZ; 2Moran Eye Center, University of Utah School of Medicine, Salt Lake City, UT, USAPurpose: A growing number of diabetic patients request laser in situ keratomileusis (LASIK) for elective vision correction each year. While the United States Food and Drug Administration considers diabetes a relative contraindication to LASIK surgery, there are several reports in the literature of LASIK being performed safely in this patient population. The purpose of this review was to examine whether diabetes should still be considered a contraindication to LASIK surgery by reviewing the ocular and systemic complications of diabetes, and examining the existing data on the outcomes of LASIK in diabetic patients.Methods: A literature review was conducted through PubMed, Medline, and Ovid to identify any study on LASIK surgery in patients with diabetes mellitus. This search was conducted without date restrictions. The search used the Medical Subject Headings (MeSH®) term LASIK linked by the word “and” to the following MeSH and natural language terms: diabetes, diabetes mellitus, systemic disease, and contraindications. Abstracts for all studies meeting initial search criteria were reviewed for relevance. There were no prospective clinical studies identified. Three retrospective studies were identified. Key sources from these papers were identified, reviewed, and included as appropriate. An additional literature search was conducted to identify any study of ocular surgery on patients with diabetes using the MeSH terms refractive surgery, photorefractive keratectomy, radial keratotomy, cataract surgery, vitrectomy, and iridectomy linked by the word “and” to the following MeSH terms: diabetes, diabetes mellitus, and systemic disease. This search was conducted without date restrictions. Abstracts of studies meeting the initial search criteria were reviewed and articles deemed relevant to the subject were included in this review.Conclusion: LASIK may be safe in diabetic patients with tight glycemic control and no ocular or systemic complications.Keywords: diabetes mellitus, diabetic keratopathy, diabetic corneal neuropathy, refractive surgery, LASIK surgeryhttp://www.dovepress.com/laser-in-situ-keratomileusis-in-patients-with-diabetes-mellitus-a-revi-a11256
spellingShingle Simpson RG
Moshirfar M
Edmonds JN
Christiansen SM
Laser in-situ keratomileusis in patients with diabetes mellitus: a review of the literature
Clinical Ophthalmology
title Laser in-situ keratomileusis in patients with diabetes mellitus: a review of the literature
title_full Laser in-situ keratomileusis in patients with diabetes mellitus: a review of the literature
title_fullStr Laser in-situ keratomileusis in patients with diabetes mellitus: a review of the literature
title_full_unstemmed Laser in-situ keratomileusis in patients with diabetes mellitus: a review of the literature
title_short Laser in-situ keratomileusis in patients with diabetes mellitus: a review of the literature
title_sort laser in situ keratomileusis in patients with diabetes mellitus a review of the literature
url http://www.dovepress.com/laser-in-situ-keratomileusis-in-patients-with-diabetes-mellitus-a-revi-a11256
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