A meta-analysis of ozone effect on tooth bleaching
Abstract This systematic review assessed the effectiveness of ozone (O3) in the color change of in-office tooth bleaching in vital teeth (TB) and the sensitivity control. Only randomized controlled clinical trials were included. Seven databases were used as primary search sources, and three addition...
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| Format: | Article |
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Nature Portfolio
2021-06-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-021-92733-8 |
| _version_ | 1818736191138168832 |
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| author | Lia Dietrich Marcelo Dias Moreira de Assis Costa Cauane Blumenberg Gustavo G. Nascimento Luiz Renato Paranhos Gisele Rodrigues da Silva |
| author_facet | Lia Dietrich Marcelo Dias Moreira de Assis Costa Cauane Blumenberg Gustavo G. Nascimento Luiz Renato Paranhos Gisele Rodrigues da Silva |
| author_sort | Lia Dietrich |
| collection | DOAJ |
| description | Abstract This systematic review assessed the effectiveness of ozone (O3) in the color change of in-office tooth bleaching in vital teeth (TB) and the sensitivity control. Only randomized controlled clinical trials were included. Seven databases were used as primary search sources, and three additional sources were searched to capture the "grey literature" partially. The JBI tool was used to assess the risk of bias. TB was assessed using the ΔELab color change metric comparing tooth color pre- and post-bleaching. We meta-analyzed the ΔELab estimates per method and calculated the absolute standardized mean difference using random-effect models. The GRADE approach assessed the certainty of the evidence. The ΔELab estimates ranged from 1.28 when the O3 was used alone to 6.93 when combined with hydrogen peroxide (HP). Two studies compared O3 and HP alone, but their TB was similar (SMD = − 0.02; 95%CI: − 0.54; 0.49). The bleaching effectiveness for the combination of O3 + HP compared to HP was similar (SMD = 0.38; 95%CI: − 0.04; 0.81). Thus, based on the available literature, our findings suggest that O3 is not superior to the conventional technique using HP on the change of tooth color. The O3 did not present sensitivity when used alone. When O3 was used in combination with HP, patients reported hypersensitivity only when O3 was applied before HP, i.e., no sensitivity was perceived when O3 was applied after HP. |
| first_indexed | 2024-12-18T00:33:13Z |
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| id | doaj.art-8691b9c30881497e8929862f9992a9c4 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-18T00:33:13Z |
| publishDate | 2021-06-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-8691b9c30881497e8929862f9992a9c42022-12-21T21:27:05ZengNature PortfolioScientific Reports2045-23222021-06-0111111210.1038/s41598-021-92733-8A meta-analysis of ozone effect on tooth bleachingLia Dietrich0Marcelo Dias Moreira de Assis Costa1Cauane Blumenberg2Gustavo G. Nascimento3Luiz Renato Paranhos4Gisele Rodrigues da Silva5School of Dentistry, Federal University of UberlândiaSchool of Dentistry, Federal University of UberlândiaFederal University of PelotasSection of Periodontology, Department of Dentistry and Oral Health, Aarhus UniversityDepartment of Preventive and Social Dentistry, School of Dentistry, Federal University of UberlândiaDepartment of Operative Dentistry and Dental Materials, Dental School, Federal University of UberlândiaAbstract This systematic review assessed the effectiveness of ozone (O3) in the color change of in-office tooth bleaching in vital teeth (TB) and the sensitivity control. Only randomized controlled clinical trials were included. Seven databases were used as primary search sources, and three additional sources were searched to capture the "grey literature" partially. The JBI tool was used to assess the risk of bias. TB was assessed using the ΔELab color change metric comparing tooth color pre- and post-bleaching. We meta-analyzed the ΔELab estimates per method and calculated the absolute standardized mean difference using random-effect models. The GRADE approach assessed the certainty of the evidence. The ΔELab estimates ranged from 1.28 when the O3 was used alone to 6.93 when combined with hydrogen peroxide (HP). Two studies compared O3 and HP alone, but their TB was similar (SMD = − 0.02; 95%CI: − 0.54; 0.49). The bleaching effectiveness for the combination of O3 + HP compared to HP was similar (SMD = 0.38; 95%CI: − 0.04; 0.81). Thus, based on the available literature, our findings suggest that O3 is not superior to the conventional technique using HP on the change of tooth color. The O3 did not present sensitivity when used alone. When O3 was used in combination with HP, patients reported hypersensitivity only when O3 was applied before HP, i.e., no sensitivity was perceived when O3 was applied after HP.https://doi.org/10.1038/s41598-021-92733-8 |
| spellingShingle | Lia Dietrich Marcelo Dias Moreira de Assis Costa Cauane Blumenberg Gustavo G. Nascimento Luiz Renato Paranhos Gisele Rodrigues da Silva A meta-analysis of ozone effect on tooth bleaching Scientific Reports |
| title | A meta-analysis of ozone effect on tooth bleaching |
| title_full | A meta-analysis of ozone effect on tooth bleaching |
| title_fullStr | A meta-analysis of ozone effect on tooth bleaching |
| title_full_unstemmed | A meta-analysis of ozone effect on tooth bleaching |
| title_short | A meta-analysis of ozone effect on tooth bleaching |
| title_sort | meta analysis of ozone effect on tooth bleaching |
| url | https://doi.org/10.1038/s41598-021-92733-8 |
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