FOVEA: a new program to standardize the measurement of foveal pit morphology
The fovea is one of the most studied retinal specializations in vertebrates, which consists of an invagination of the retinal tissue with high packing of cone photoreceptors, leading to high visual resolution. Between species, foveae differ morphologically in the depth and width of the foveal pit an...
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| Format: | Article |
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PeerJ Inc.
2016-04-01
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| Series: | PeerJ |
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| Online Access: | https://peerj.com/articles/1785.pdf |
| _version_ | 1797420775667400704 |
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| author | Bret A. Moore Innfarn Yoo Luke P. Tyrrell Bedrich Benes Esteban Fernandez-Juricic |
| author_facet | Bret A. Moore Innfarn Yoo Luke P. Tyrrell Bedrich Benes Esteban Fernandez-Juricic |
| author_sort | Bret A. Moore |
| collection | DOAJ |
| description | The fovea is one of the most studied retinal specializations in vertebrates, which consists of an invagination of the retinal tissue with high packing of cone photoreceptors, leading to high visual resolution. Between species, foveae differ morphologically in the depth and width of the foveal pit and the steepness of the foveal walls, which could influence visual perception. However, there is no standardized methodology to measure the contour of the foveal pit across species. We present here FOVEA, a program for the quantification of foveal parameters (width, depth, slope of foveal pit) using images from histological cross-sections or optical coherence tomography (OCT). FOVEA is based on a new algorithm to detect the inner retina contour based on the color variation of the image. We evaluated FOVEA by comparing the fovea morphology of two Passerine birds based on histological cross-sections and its performance with data from previously published OCT images. FOVEA detected differences between species and its output was not significantly different from previous estimates using OCT software. FOVEA can be used for comparative studies to better understand the evolution of the fovea morphology in vertebrates as well as for diagnostic purposes in veterinary pathology. FOVEA is freely available for academic use and can be downloaded at: http://estebanfj.bio.purdue.edu/fovea. |
| first_indexed | 2024-03-09T07:06:25Z |
| format | Article |
| id | doaj.art-86946acc57604426b425703952a40507 |
| institution | Directory Open Access Journal |
| issn | 2167-8359 |
| language | English |
| last_indexed | 2024-03-09T07:06:25Z |
| publishDate | 2016-04-01 |
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| spelling | doaj.art-86946acc57604426b425703952a405072023-12-03T09:30:33ZengPeerJ Inc.PeerJ2167-83592016-04-014e178510.7717/peerj.1785FOVEA: a new program to standardize the measurement of foveal pit morphologyBret A. Moore0Innfarn Yoo1Luke P. Tyrrell2Bedrich Benes3Esteban Fernandez-Juricic4Department of Biological Sciences, Purdue University, West Lafayette, IN, USADepartment of Computer Graphics Technology, Purdue University, West Lafayette, IN, USADepartment of Biological Sciences, Purdue University, West Lafayette, IN, USADepartment of Computer Graphics Technology, Purdue University, West Lafayette, IN, USADepartment of Biological Sciences, Purdue University, West Lafayette, IN, USAThe fovea is one of the most studied retinal specializations in vertebrates, which consists of an invagination of the retinal tissue with high packing of cone photoreceptors, leading to high visual resolution. Between species, foveae differ morphologically in the depth and width of the foveal pit and the steepness of the foveal walls, which could influence visual perception. However, there is no standardized methodology to measure the contour of the foveal pit across species. We present here FOVEA, a program for the quantification of foveal parameters (width, depth, slope of foveal pit) using images from histological cross-sections or optical coherence tomography (OCT). FOVEA is based on a new algorithm to detect the inner retina contour based on the color variation of the image. We evaluated FOVEA by comparing the fovea morphology of two Passerine birds based on histological cross-sections and its performance with data from previously published OCT images. FOVEA detected differences between species and its output was not significantly different from previous estimates using OCT software. FOVEA can be used for comparative studies to better understand the evolution of the fovea morphology in vertebrates as well as for diagnostic purposes in veterinary pathology. FOVEA is freely available for academic use and can be downloaded at: http://estebanfj.bio.purdue.edu/fovea.https://peerj.com/articles/1785.pdfFoveaRetinaFoveal pitComparative studies |
| spellingShingle | Bret A. Moore Innfarn Yoo Luke P. Tyrrell Bedrich Benes Esteban Fernandez-Juricic FOVEA: a new program to standardize the measurement of foveal pit morphology PeerJ Fovea Retina Foveal pit Comparative studies |
| title | FOVEA: a new program to standardize the measurement of foveal pit morphology |
| title_full | FOVEA: a new program to standardize the measurement of foveal pit morphology |
| title_fullStr | FOVEA: a new program to standardize the measurement of foveal pit morphology |
| title_full_unstemmed | FOVEA: a new program to standardize the measurement of foveal pit morphology |
| title_short | FOVEA: a new program to standardize the measurement of foveal pit morphology |
| title_sort | fovea a new program to standardize the measurement of foveal pit morphology |
| topic | Fovea Retina Foveal pit Comparative studies |
| url | https://peerj.com/articles/1785.pdf |
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