Spatial subsetting enables integrative modeling of oral squamous cell carcinoma multiplex imaging data

Spatial subsetting enables integrative modeling of oral squamous cell carcinoma multiplex imaging data

Summary: Oral squamous cell carcinoma (OSCC), a prevalent and aggressive neoplasm, poses a significant challenge due to poor prognosis and limited prognostic biomarkers. Leveraging highly multiplexed imaging mass cytometry, we investigated the tumor immune microenvironment (TIME) in OSCC biopsies, c...

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Bibliographic Details
Main Authors: Jakob Einhaus, Dyani K. Gaudilliere, Julien Hedou, Dorien Feyaerts, Michael G. Ozawa, Masaki Sato, Edward A. Ganio, Amy S. Tsai, Ina A. Stelzer, Karl C. Bruckman, Jonas N. Amar, Maximilian Sabayev, Thomas A. Bonham, Joshua Gillard, Maïgane Diop, Amelie Cambriel, Zala N. Mihalic, Tulio Valdez, Stanley Y. Liu, Leticia Feirrera, David K. Lam, John B. Sunwoo, Christian M. Schürch, Brice Gaudilliere, Xiaoyuan Han
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:iScience
Subjects:
Immunology
Cell biology
Cancer
Machine learning
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223025634

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