GLAUCOMA PROGRESSION. IMPACT OF RISK FACTORS ON THE DISEASE
The aim of the study is to assess the effect of systemic and local risk factors on the rate of glaucoma progression, the specificity and informative nature of ophthalmological studies for assessment of the rate of glaucoma progression.Material and methods. A retrospective analysis of the medical cas...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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Russian Academy of Sciences, Siberian Branch Publishing House
2020-03-01
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| Series: | Сибирский научный медицинский журнал |
| Subjects: | |
| Online Access: | https://sibmed.elpub.ru/jour/article/view/341 |
| _version_ | 1826575768789975040 |
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| author | A. Zh. Fursova N. V. Litvinova S. F. Kraeva N. L. Ivanova O. G. Gusarevich |
| author_facet | A. Zh. Fursova N. V. Litvinova S. F. Kraeva N. L. Ivanova O. G. Gusarevich |
| author_sort | A. Zh. Fursova |
| collection | DOAJ |
| description | The aim of the study is to assess the effect of systemic and local risk factors on the rate of glaucoma progression, the specificity and informative nature of ophthalmological studies for assessment of the rate of glaucoma progression.Material and methods. A retrospective analysis of the medical case histories and outpatient charts of 217 patients (268 eyes) for the period from 2014 to 2017 was conducted. The patients with primary open-angle glaucoma having at least 5 Humphrey field-of-view (24-2) studies and optic coherence tomography of the optic nerve disk and retina with a guided progression analysis (GPA) function (SD-OCT) were included in the study. The patients were divided into 2 groups: with rapid progression (more than 1 dB per year, 144 eyes (103 patients)) and slow progression (less than 1 dB per year, 124 eyes (114 patients)). The data of standard ophthalmological methods of investigation (visometry, ophthalmoscopy, biomicroscopy, measurement of intraocular pressure (IOP) according to Maklakov) were additionally analyzed. Demographic and clinical data were assessed: gender, age, cornea central thickness, refraction, IOP, glucocorticosteroid intake, cardiovascular diseases presence, arterial hypertension, arterial hypotension, local hypotensive therapy. Results and discussion. The analysis revealed the main risk factors in glaucoma progression, which include age, cardiovascular diseases presence, high initial IOP values, pronounced functional changes in thevisual fields (lower mean deviation), pseudoexfoliation syndrome. |
| first_indexed | 2024-03-08T14:34:07Z |
| format | Article |
| id | doaj.art-8699f2c406724f71800e3152f1790ea2 |
| institution | Directory Open Access Journal |
| issn | 2410-2512 2410-2520 |
| language | Russian |
| last_indexed | 2025-03-14T13:19:57Z |
| publishDate | 2020-03-01 |
| publisher | Russian Academy of Sciences, Siberian Branch Publishing House |
| record_format | Article |
| series | Сибирский научный медицинский журнал |
| spelling | doaj.art-8699f2c406724f71800e3152f1790ea22025-02-28T13:43:55ZrusRussian Academy of Sciences, Siberian Branch Publishing HouseСибирский научный медицинский журнал2410-25122410-25202020-03-01401788610.15372/SSMJ20200111238GLAUCOMA PROGRESSION. IMPACT OF RISK FACTORS ON THE DISEASEA. Zh. Fursova0N. V. Litvinova1S. F. Kraeva2N. L. Ivanova3O. G. Gusarevich4State Novosibirsk Regional Clinical Hospital, Novosibirsk State Medical University of Minzdrav of RussiaState Novosibirsk Regional Clinical HospitalState Novosibirsk Regional Clinical HospitalState Novosibirsk Regional Clinical HospitalState Novosibirsk Regional Clinical Hospital, Novosibirsk State Medical University of Minzdrav of RussiaThe aim of the study is to assess the effect of systemic and local risk factors on the rate of glaucoma progression, the specificity and informative nature of ophthalmological studies for assessment of the rate of glaucoma progression.Material and methods. A retrospective analysis of the medical case histories and outpatient charts of 217 patients (268 eyes) for the period from 2014 to 2017 was conducted. The patients with primary open-angle glaucoma having at least 5 Humphrey field-of-view (24-2) studies and optic coherence tomography of the optic nerve disk and retina with a guided progression analysis (GPA) function (SD-OCT) were included in the study. The patients were divided into 2 groups: with rapid progression (more than 1 dB per year, 144 eyes (103 patients)) and slow progression (less than 1 dB per year, 124 eyes (114 patients)). The data of standard ophthalmological methods of investigation (visometry, ophthalmoscopy, biomicroscopy, measurement of intraocular pressure (IOP) according to Maklakov) were additionally analyzed. Demographic and clinical data were assessed: gender, age, cornea central thickness, refraction, IOP, glucocorticosteroid intake, cardiovascular diseases presence, arterial hypertension, arterial hypotension, local hypotensive therapy. Results and discussion. The analysis revealed the main risk factors in glaucoma progression, which include age, cardiovascular diseases presence, high initial IOP values, pronounced functional changes in thevisual fields (lower mean deviation), pseudoexfoliation syndrome.https://sibmed.elpub.ru/jour/article/view/341rate of glaucoma progressionoptical coherence tomographyhumphrey visual fieldsintraocular pressureintraocular risk factors |
| spellingShingle | A. Zh. Fursova N. V. Litvinova S. F. Kraeva N. L. Ivanova O. G. Gusarevich GLAUCOMA PROGRESSION. IMPACT OF RISK FACTORS ON THE DISEASE Сибирский научный медицинский журнал rate of glaucoma progression optical coherence tomography humphrey visual fields intraocular pressure intraocular risk factors |
| title | GLAUCOMA PROGRESSION. IMPACT OF RISK FACTORS ON THE DISEASE |
| title_full | GLAUCOMA PROGRESSION. IMPACT OF RISK FACTORS ON THE DISEASE |
| title_fullStr | GLAUCOMA PROGRESSION. IMPACT OF RISK FACTORS ON THE DISEASE |
| title_full_unstemmed | GLAUCOMA PROGRESSION. IMPACT OF RISK FACTORS ON THE DISEASE |
| title_short | GLAUCOMA PROGRESSION. IMPACT OF RISK FACTORS ON THE DISEASE |
| title_sort | glaucoma progression impact of risk factors on the disease |
| topic | rate of glaucoma progression optical coherence tomography humphrey visual fields intraocular pressure intraocular risk factors |
| url | https://sibmed.elpub.ru/jour/article/view/341 |
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