Fabrication of polymer-based stents: Impact of test specimen manufacturing protocol
Various manufacturing techniques are available for polymer stent fabrication. Polymer semi-finished products can be prepared using solvent based methods, e.g. dip coating, as well as thermal processes, e.g. extrusion. These different methods may lead to an altered polymer crystal structure, resultin...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2023-09-01
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| Series: | Current Directions in Biomedical Engineering |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/cdbme-2023-1095 |
| _version_ | 1797646316642238464 |
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| author | Koper Daniela Kaule Sebastian Grabow Niels Schmitz Klaus-Peter Oschatz Stefan |
| author_facet | Koper Daniela Kaule Sebastian Grabow Niels Schmitz Klaus-Peter Oschatz Stefan |
| author_sort | Koper Daniela |
| collection | DOAJ |
| description | Various manufacturing techniques are available for polymer stent fabrication. Polymer semi-finished products can be prepared using solvent based methods, e.g. dip coating, as well as thermal processes, e.g. extrusion. These different methods may lead to an altered polymer crystal structure, resulting in a different deformation mechanism during mechanical stress. For the material property characterization needed for implant development, the test specimens usually are prepared using laser-cut or die-cut methods. Due to these different preparation protocols, a change in polymer microstructure, causing a material property variation, may also result. For this purpose, comparison of laser-cut versus die-cut of PLLA films has been performed. PLLA films have been prepared by dip-coating and were evaluated with respect to structural, thermal, and mechanical properties. In this study, a combination of uniaxial tensile tests, SEM and DSC studies was used. The results of the mechanical tests showed drastic differences in the elongations at break of die-cut specimens compared to laser-cut ones. The results point out formation of complex crystal structures during the manufacturing process. By the use of SEM imaging and DSC measurements, we were able to attribute these changes to the different plastic deformation mechanisms. |
| first_indexed | 2024-03-11T15:00:55Z |
| format | Article |
| id | doaj.art-869b0785e07348be85f5d79929ced389 |
| institution | Directory Open Access Journal |
| issn | 2364-5504 |
| language | English |
| last_indexed | 2024-03-11T15:00:55Z |
| publishDate | 2023-09-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Current Directions in Biomedical Engineering |
| spelling | doaj.art-869b0785e07348be85f5d79929ced3892023-10-30T07:58:12ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042023-09-019137938210.1515/cdbme-2023-1095Fabrication of polymer-based stents: Impact of test specimen manufacturing protocolKoper Daniela0Kaule Sebastian1Grabow Niels2Schmitz Klaus-Peter3Oschatz Stefan4Institute for ImplantTechnology and Biomaterials e.V. Friedrich-Barnewitz-Str. 4, Rostock, GermanyInstitute for ImplantTechnology and Biomaterials e.V. Friedrich-Barnewitz-Str. 4, Rostock, GermanyInstitute for Biomedical Engineering, Rostock University Medical Center, Friedrich- Barnewitz-Str. 4, Rostock, GermanyInstitute for ImplantTechnology and Biomaterials e.V. Friedrich-Barnewitz-Str. 4, Rostock, GermanyInstitute for Biomedical Engineering, Rostock University Medical Center, Friedrich- Barnewitz-Str. 4, Rostock, GermanyVarious manufacturing techniques are available for polymer stent fabrication. Polymer semi-finished products can be prepared using solvent based methods, e.g. dip coating, as well as thermal processes, e.g. extrusion. These different methods may lead to an altered polymer crystal structure, resulting in a different deformation mechanism during mechanical stress. For the material property characterization needed for implant development, the test specimens usually are prepared using laser-cut or die-cut methods. Due to these different preparation protocols, a change in polymer microstructure, causing a material property variation, may also result. For this purpose, comparison of laser-cut versus die-cut of PLLA films has been performed. PLLA films have been prepared by dip-coating and were evaluated with respect to structural, thermal, and mechanical properties. In this study, a combination of uniaxial tensile tests, SEM and DSC studies was used. The results of the mechanical tests showed drastic differences in the elongations at break of die-cut specimens compared to laser-cut ones. The results point out formation of complex crystal structures during the manufacturing process. By the use of SEM imaging and DSC measurements, we were able to attribute these changes to the different plastic deformation mechanisms.https://doi.org/10.1515/cdbme-2023-1095pllastent fabricationdip-coating processlaser-cutdie-cutmelting zonemechanical properties |
| spellingShingle | Koper Daniela Kaule Sebastian Grabow Niels Schmitz Klaus-Peter Oschatz Stefan Fabrication of polymer-based stents: Impact of test specimen manufacturing protocol Current Directions in Biomedical Engineering plla stent fabrication dip-coating process laser-cut die-cut melting zone mechanical properties |
| title | Fabrication of polymer-based stents: Impact of test specimen manufacturing protocol |
| title_full | Fabrication of polymer-based stents: Impact of test specimen manufacturing protocol |
| title_fullStr | Fabrication of polymer-based stents: Impact of test specimen manufacturing protocol |
| title_full_unstemmed | Fabrication of polymer-based stents: Impact of test specimen manufacturing protocol |
| title_short | Fabrication of polymer-based stents: Impact of test specimen manufacturing protocol |
| title_sort | fabrication of polymer based stents impact of test specimen manufacturing protocol |
| topic | plla stent fabrication dip-coating process laser-cut die-cut melting zone mechanical properties |
| url | https://doi.org/10.1515/cdbme-2023-1095 |
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